[3dem] ab initio reconstruction of multiple structures when each structure has a different point group symmetry
Peter Doerschuk
pd83 at cornell.edu
Mon Aug 31 11:00:42 PDT 2026
Dear 3DEM: For an engineering problem, I would like to do simultaneous ab initio reconstruction of two structures with different point group symmetries from a stack of unlabeled cryo EM images. For instance, one structure has icosahedral symmetry, one structure has tetrahedral symmetry, and which images belong to which structure is not known. I see e2refinemulti.html in EMAN2 but e2refinemulti.html is for refinement while I need ab initio model generation. I would be very grateful for advice! Thank you very much! Best regards, Peter Doerschuk (pd83 at cornell.edu)
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