[3dem] Single Electron Counting, The Measurement Problem, Symmetric Sampling

Marin van Heel marin.vanheel at gmail.com
Sat Oct 4 15:10:45 PDT 2025


Dear All,

Electron counting cameras in Cryo-EM have an unexpected direct connection
to the Measurement Problem in Quantum Mechanics. In fact, the measurement
problem already existed in Classical Newtonian Physics due to its
Deterministic Mathematical Axioms and is not specifically tied to Quantum
Mechanics. The Measurement Problem also existed in Shannon’s sampling
theorem. All measurements, and not only those in Electron Microscopy must
adhere to symmetric-sampling rules. Check the link to a series of papers:

https://urldefense.com/v3/__https://www.linkedin.com/feed/update/urn:li:activity:7379515419424022528/__;!!Mih3wA!E-gVvpSJ0PZKrmob6DUKkdRWI9bIcyBKAqn-ncUvr505v_8l4dULRWi9de7q_GpGi11xEqjX_-aEteJYYy7akbqwxQ$ 

Sorry, I know it is tough stuff…

Marin
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