[3dem] Call for papers M&M 2021

[Giovanna Scapin]

Dear all

The Microscopy & Microanalysis 2021 meeting will be held in Pittsburgh, Pennsylvania, August 1-5. In addition to 4 days of the world's largest Microscopy products and services commercial expo hall, M&M 2021 will have over 1200 platform and poster sessions, Pre-Meeting Congresses, Short Courses, and a variety of other workshops, sessions, tutorials, and networking events.  For a complete description of the symposium please see the following link: https://urldefense.com/v3/__https://www.microscopy.org/MandM/2021/meetings/MM2021_CallforPapers.pdf__;!!Mih3wA!TbbIbm57v0vmdGAG68FPjcOz5o3vRNvpwjSvkg5IaJFPIAfEw0TacH3arbsARyX_fQ$ .
 
We would like to invite you to submit an abstract for the Biological Sciences Symposium “CryoEM in Drug Discovery”, which will focus on the potential applications and uses of cryoEM at the R&D stages of drug discovery. Topics of interest are (and not limited to) the use of cryo-EM structures to drive structure-based drug discovery, integration of cryoEM and modeling in small molecule design and optimization, epitope mapping, methods aimed at optimizing (faster, cheaper, better) the process, microED and tomography.  We encourage both academic and industrial researchers to submit a paper.  Young researchers (students, post-doc and professional technical staff members) can also apply for M&M Meeting Awards and memorial awards, which consist of full meeting registration and up to $1,000 for travel-related expenses.
 
Among the submitted abstracts 10 will be selected for oral presentations (15 minutes each with 5 minutes for discussion).  All abstracts can of course be part of the poster sessions.
 
Deadline for abstract submission is  February 18, 2021.  Information on how to submit the abstract can be found in the meeting homepage (https://urldefense.com/v3/__https://www.microscopy.org/MandM/2021/__;!!Mih3wA!TbbIbm57v0vmdGAG68FPjcOz5o3vRNvpwjSvkg5IaJFPIAfEw0TacH3arbtUSyYmFA$ ) We sincerely hope that you will join us at M&M 2021
 
Sincerely
 
Giovanna Scapin
Christel Verboven
Leah Frye
 
B08 - Cryo-EM in Drug Discovery
ORGANIZERS:
Leah Frye, Schrodinger
Giovanna Scapin, NanoImaging Services
Christel Verboven, Thermo Fisher Scientific
 
Recent advances in cryo-EM technology have resulted in the ability to obtain structures of pharmaceutically relevant proteins with atomic level resolutions in a timely fashion. Importantly, cryo-EM greatly expands the availability of structures for large protein assemblies and membrane bound proteins which have been difficult to access via X-ray crystallography. This symposium will focus on the use of cryo-EM in drug discovery. Presentations will describe projects utilizing cryo-EM structures to drive structure-based drug discovery efforts for the optimization of potency and selectivity, including selectivity against ADMET targets, in projects from both industrial and academic groups.

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