[3dem] Announcing major new release, EMAN2.3
Ludtke, Steven J.
sludtke at bcm.edu
Fri Apr 26 07:15:54 PDT 2019
Hi all,
a brief announcement of a new major release: EMAN2.3 (http://eman2.org), with major new features. As always, the distribution also includes SPARX (http://sparx-em.org) and the release of SPHIRE 1.2 (http://sphire.mpg.de). Releases are coordinated among the packages.
New features in EMAN2.3 include:
* A complete CryoET pipeline from tilt series alignment through subnanometer resolution hybrid subtomogram averaging
* fiducial-less fully automated tilt series alignment (also works with fiducials)
* rapid tiled Fourier reconstruction
* full tilt/geometry aware CTF correction
* multi class 3-D particle picker with new ties to deep-learning annotation
* SGD automatic initial model generation
* traditional 3-D subtomogram averaging
* per-particle per-tilt hybrid subtomogram/single particle reconstruction to subnanometer resolution
* A new switchable filter in e2boxer making it dramatically easier to distinguish particles in images
* New improvements to bispectral classification for 2-D unsupervised classification and 3-D refinement
* Focused classification in 3-D refinement available from the workflow interface
* Improvements to e2extractsubparticles as an alternative to focused classification
* Upgrade from Qt4 to Qt5 as part of the process of transitioning to Python3 over the next year
* Many minor bugfixes
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Steven Ludtke, Ph.D. <sludtke at bcm.edu> Baylor College of Medicine
Charles C. Bell Jr., Professor of Structural Biology
Dept. of Biochemistry and Molecular Biology (www.bcm.edu/biochem)
Academic Director, CryoEM Core (cryoem.bcm.edu)
Co-Director CIBR Center (www.bcm.edu/research/cibr)
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