[3dem] SIMPLE 2.0 released
Hans Olof Elmlund
hael at stanford.edu
Mon Aug 12 20:21:50 PDT 2013
Dear Colleagues:
We hereby announce the release of SIMPLE 2.0. The common lines-based routines have been replaced
with a new probabilistic image alignment algorithm PRIME (Probabilistic Initial 3D Model Generation
for Single-Particle Cryo-Electron Microscopy) that was presented on the 3DEM Gordon conference. The
article is available at http://www.sciencedirect.com/science/article/pii/S0969212613002505 and the
software can be downloaded at http://simple.stanford.edu/. The SIMPLE 2.0 distribution currently
contains the starting model generation procedure (PRIME), a clustering algorithm, and a bunch of
utility programs. Improved algorithms for heterogeneity analysis and refinement are underway.
Happy Processing!
Hans & Dominika
--
Hans Elmlund
Postdoctoral Fellow
Roger Kornberg Laboratory
Dept. of Structural Biology
Stanford University School of Medicine
Fairchild Bldg - 1st floor, D117
299 Campus Dr.,
Stanford CA, 94305-5126
USA
phone: 650 284 63 19
e-mail: hael at stanford.edu
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