[3dem] 2 positions at NYSBC
David Stokes
stokes at nyu.edu
Fri May 4 09:58:16 PDT 2012
*Research Scientist Position in the Cryo-Electron Microscopy Facility at
the New York Structural Biology Center*
The New York Structural Biology Center (NYSBC) seeks an experienced
electron microscopist to join the staff of its Cryo-Electron Microscope
Facility (http://cryoem.nysbc.org). The NYSBC is a shared center that
supports state-of-the-art research in cryo-EM, NMR, and X-ray. Cryo-EM
facilities include four transmission electron microscopes and a
dual-beam scanning electron microscope, which support projects involving
electron tomography, single particle analysis and electron
crystallography of both stained and frozen-hydrated samples. Projects
focus on 3D reconstruction of biological assemblies ranging from the
atomic structure of membrane proteins, to the subunit organization in
macromolecular complexes and the cellular anatomy of developing
organisms.Implementation of new technologies is an ongoing interest at
NYSBC and, with the dual-beam microscope, NYSBC plans to expand the
scale of 3D reconstructions to encompass the characterization of entire
cells and their distributions within their native tissue. To assist in
these developments, NYSBC seeks a individual with postdoctoral
experience in biological electron microscopy and image
reconstruction.This individual will carry out experiments in support of
collaborative projects with affiliated investigators and will also have
opportunities to pursue independent research projects. The individual
should be capable of multitasking, should enjoy working with other
people, should have a good working knowledge of electron microscopes and
a strong research background. Good communication skills are essential.
*Postdoctoral Position for a Membrane Protein Electron Microscopist *
A postdoctoral position for a highly motivatedelectron microscopist is
available immediately in the laboratory of David Stokes at the New York
Structural Biology Center(http://cryoem.nysbc.org) in New York City. The
successful applicant will work for the Transcontinental Electron
Microscopy Initiative for Membrane Protein Structure (TEMIMPS;
http://temimps.nysbc.org). TEMIMPS is funded by the NIH Protein
Structure Initiative for development and implementation of
high-throughput and high-resolution approaches to structure
determination of membrane proteins using electron cryo-microscopy and 2D
membrane crystals. TEMIMPS is composed of six research groups with
combined expertise in membrane protein production, membrane
crystallization, electron microscopy, image processing, and structure
determination. Groups at Mt. Sinai School of Medicine, New York
University and NYSBC work closely together. The group at Mt. Sinai
focuses on production of purified membrane protein targets, whereas the
group at NYSBC uses a high-throughput pipeline to screen crystallization
conditions. The open position at NYSBC will involve crystallization of
membrane proteins 3D reconstruction using methods of electron
crystallography. The NYSBC is well equipped for all aspects of this
project and hosts superlative facilities for electron cryo-microscopy.
Candidates must hold a Ph.D. in Molecular Biology, Biochemistry,
Biophysics, Structural Biology or a related field. Strong research
experience in membrane protein biochemistry is highly desirable. In
addition, the candidate must have strong interpersonal, organizational
and communication skills in order to facilitate intimate collaboration
with other research groups.
Qualified applicants should send a curriculum vitae and names of three
references to David Stokes (stokes at nysbc.org). Salary will be
commensurate with experience. Both positions are currently open and
applications will be reviewed continuously until the positions are filled.
--
David L. Stokes
Skirball Institute, NYU Medical Center
tel: 212-263-1580
http://saturn.med.nyu.edu/~stokes
----
New York Structural Biology Center
tel: 212-939-0660 x9116
http://nysbc.org/
fax: 212-263-2150
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