[3dem] Quips about greasy pockets
Gerard DVD Kleywegt
gerard at xray.bmc.uu.se
Wed Sep 14 08:57:20 PDT 2011
Hi all,
As you may recall, the Protein Data Bank in Europe (PDBe; pdbe.org) regularly
produces Quips, short stories about QUite Interesting Pdb Structures
(pdbe.org/quips). Quips address biologically interesting aspects of one or more
PDB entries, coupled with interactive graphics views and often a mini-tutorial
or suggestions for further exploration using PDBe services and resources.
Today another Quips episode was released. It is about autotaxins,
physiologically important proteins that are pursued as anti-cancer drug
targets. This Quips was developed together with scientists from the Netherlands
Cancer Institute (Tassos Perrakis and Wouter Moolenaar) to accompany their
review paper in Nature Reviews Molecular Cell Biology on autotaxin structure
and function that was also published today.
- For the Quips story ("Autotaxins: inhibiting a greasy pocket"), go to:
http://pdbe.org/quips?story=Autotaxin
- For the review paper ("Insights into autotaxin: how to produce and present a
lipid mediator"), go to:
http://www.nature.com/nrm/journal/vaop/ncurrent/full/nrm3188.html
---
If you have an interesting structure whose story you would like to tell (with
our help) in the form of a Quips episode, please contact us at pdbe at ebi.ac.uk
--Gerard
---
Gerard J. Kleywegt, PDBe, EMBL-EBI, Hinxton, UK
gerard at ebi.ac.uk ..................... pdbe.org
Secretary: Pauline Haslam pdbe_admin at ebi.ac.uk
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