[3dem] SPIDER support
Joachim Frank
jf2192 at columbia.edu
Tue Jun 15 09:25:37 PDT 2010
Recently, SPIDER support, after continuous funding by NIH since 1982,
has experienced two setbacks. First, the P41 grant that funded the
Albany Resource on Visualization of Biological Complexity (RVBC) and
supported the package as one of its missions was not renewed by
NIH/NCRR. Second, Dean Leith's R01 application for support and
development of the package under an NIH program specially designed to
deal with software widely used by the research community was
unsuccessful (a fate shared with David Mastronarde's application for
support of IMOD). It is the judgment of the Wadsworth investigators
that revised submissions for the P41 or R01 grant application are not
likely to succeed, at least at this time, and will not be pursued.
We would like to clarify that we intend, with the help of all active
SPIDER user groups and with high priority, to address the need for
continued centralized support, distribution, as well as further
development of the package. Many EM groups have made a large investment
in batch files that address their specific programming needs. Despite
its Fortran coding, SPIDER is widely perceived as a rich and very
flexible environment for developing solutions to complex problems
encountered in EM-related image processing. Significantly, SPIDER is
one of the platforms supported by Appion, a Python-based image
processing pipeline developed and distributed with Leginon by the
National Resource for Automated Molecular Microscopy (NRAMM) based at
The Scripps Research Institute.
Joachim Frank, Columbia University
Carmen Mannella, Wadsworth Center
Michael Radermacher, University of Vermont
--
Joachim Frank, Ph.D.
Howard Hughes Medical Institute Investigator,
Professor, Department of Biochemistry and Molecular Biophysics,
and Department of Biology, Columbia University,
650 W. 168th Street, P&S Black Building 2-221
New York, NY10032
(T) 212 305-9510
(F) 212 305-9500
(E) jf2192 at columbia.edu
http://www.hhmi.org/research/investigators/frank.html
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