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Hello CryoEM Researchers,</div>
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<span style="color: rgb(0, 0, 0);"><br>
Pacific Northwest CryoEM Center is offering a mechanism developed to help laboratories with
</span><span style="color: rgb(0, 0, 0); font-weight: 700;">limited or no cryo-EM resources</span><span style="color: rgb(0, 0, 0);"> enter the field of cryo-EM. PNCC's "Screening Access Mechanism" will provide users on-site access to state-of-the-art cryo-EM
resources and expertise to carry out sample preparation and optimization under close supervision of trained cryo-EM specialists.<br>
<br>
Our goal is to help users identify cryo-grid conditions that will be successful for transitioning to data collection activities provided by PNCC’s General Access mechanism or to establish the technical feasibility and provide guidance on the next states of
the project. We hope this new mechanism will enable investigators lacking access to local cryo-EM resources and help jump-start investigators interested in entering the field of cryo-EM.<br>
<br>
For more information about our "Screening Access Mechanism", go </span><span style="color: rgb(18, 100, 163);"><a style="color: rgb(18, 100, 163); margin: 0px;" data-auth="NotApplicable" data-sk="tooltip_parent" data-linkindex="0" data-ogsc="rgb(18, 100, 163)" title="https://urldefense.com/v3/__https:/pncc.labworks.org/access/choose-access-type__;!!OLyWHuc!WRbkzpZk2YzMC6e8cuCMLj79P_Y9slTq5ZshAfmSeZ_UWlYZTAMrpq9zpeRgVi3X_Ug7jJWfiIFu1i6s8tSQEr1PVA$" class="x_x_x_x_OWAAutoLink" id="OWA58bd7f1e-f5c2-7ae8-363a-6a56014543f9" href="https://urldefense.com/v3/__https:/pncc.labworks.org/access/choose-access-type__;!!OLyWHuc!WRbkzpZk2YzMC6e8cuCMLj79P_Y9slTq5ZshAfmSeZ_UWlYZTAMrpq9zpeRgVi3X_Ug7jJWfiIFu1i6s8tSQEr1PVA$">here</a></span><span style="color: rgb(0, 0, 0);">.
Applications are accepted on a monthly basis, with the next deadline for this proposal type being<b> May 1st at 11:59pm (Pacific)</b> in our portal. Step-by-step instructions on how to submit a proposal to PNCC can be found
</span><span style="color: rgb(18, 100, 163);"><a style="margin: 0px;" data-auth="NotApplicable" data-linkindex="1" data-ogsc="" title="https://pncc.labworks.org/sites/default/files/2026-01/Step-by-Step_Proposal_Submission_Guide.pdf" class="x_x_OWAAutoLink" id="OWAf02dec64-9a28-3704-65b1-e50d2b43b219" href="https://urldefense.com/v3/__https://pncc.labworks.org/sites/default/files/2026-01/Step-by-Step_Proposal_Submission_Guide.pdf__;!!Mih3wA!HfwZmXbwBb_He7Ds7NWFnh59Rj7y3c0O6tCOtN3fTHw10E0HpTZZ3sVvjFS4SKTkFtUdDfQoLnTt07pcCxiO$">here</a></span><span style="color: rgb(0, 0, 0);">.<br>
<br>
We request your help by disseminating this information to colleagues who may be interested in engaging in the field of cryo-EM.<br>
<br>
Best, </span></div>
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<p style="direction: ltr; text-align: left; text-indent: 0px; margin: 0px 0in;"><span style="font-family: Calibri, sans-serif; font-size: 11pt; color: rgb(224, 138, 50);"><b><a style="margin: 0px;" name="x_x_x_x_x__MailAutoSig">_________________________</a><br>
<a style="margin: 0px;" name="x_x_x_x_x__MailAutoSig"></a></b></span><span style="font-family: Calibri, sans-serif; font-size: 13pt; color: black;">Kjirsten Wheeler<b><br>
</b></span><span style="font-family: Calibri, sans-serif; font-size: 9pt; color: black;">PNCC Program Administrator</span></p>
<p style="direction: ltr; text-align: left; text-indent: 0px; margin: 0in;"><span style="font-family: Calibri, sans-serif; font-size: 11pt; color: rgb(224, 138, 50);"><b>Pacific Northwest</b></span><span style="font-family: Calibri, sans-serif; font-size: 11pt; color: rgb(237, 125, 49);"><b> </b></span><span style="font-family: Calibri, sans-serif; font-size: 11pt; color: rgb(91, 151, 201);"><b>Cryo-EM
Center<br>
</b></span><span style="font-family: Calibri, sans-serif; font-size: 9pt; color: black;">a
</span><span style="font-family: Calibri, sans-serif; font-size: 9pt; color: rgb(224, 138, 50);"><b>PNNL</b></span><span style="font-family: Calibri, sans-serif; font-size: 9pt; color: black;"> and
</span><span style="font-family: Calibri, sans-serif; font-size: 9pt; color: rgb(91, 151, 201);"><b>OHSU</b></span><span style="font-family: Calibri, sans-serif; font-size: 9pt; color: black;"> affiliation</span><span style="font-family: Calibri, sans-serif; font-size: 8pt; color: black;">
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