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<p class="MsoNormal">Hi All,<o:p></o:p></p>
<p class="MsoNormal"> Just like to draw attention to a bit of a Christmas treat in the form of a very interesting webinar!<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal" align="center" style="text-align:center"><b>Novel in situ cryo-TEM lamella preparation methods:<o:p></o:p></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b>Expanding cellular structural biology with CEMOVIS<o:p></o:p></b></p>
<p class="MsoNormal">With: Benoît Zuber, University of Bern<o:p></o:p></p>
<p class="MsoNormal">On: 12 Noon CET, 9<sup>th</sup> December 2025<o:p></o:p></p>
<p class="MsoNormal">Register: <a href="https://urldefense.com/v3/__https://www.thermofisher.com/uk/en/home/events/novel-sample-preparation-methods-for-in-situ-cryo-tem.html__;!!Mih3wA!E9rycH--iBdXSFNPJ0e43fmdGy0NVe-sfVmmlIiz--DAd3UfKTpcr1Iq9dPgsfPcNUMvkKUlSjOiYw0tgrQXVw2MmdTIP_4$">
https://www.thermofisher.com/uk/en/home/events/novel-sample-preparation-methods-for-in-situ-cryo-tem.html</a><o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">When using cryo-electron microscopy to image cells and tissue at high resolution, samples must be thinned to 500 nm or less to ensure electron transparency. Focused ion beam (FIB) milling has become the standard method to prepare thin samples
(lamellae), but other sample preparation methods can contribute valuable complementary insights. <br>
<br>
In this webinar, Professor Benoît Zuber of the University of Bern, Switzerland, will discuss a preparation technique called cryo-electron microscopy of vitreous sections, or CEMOVIS, in which thin sections are cut with a knife. While CEMOVIS sections sustain
damage, they can be sectioned in series, producing many orders of magnitude more imageable area than usual for PFIB. Plus, many regions of the sections contain intact molecular structures for comparison, making it possible to place results from cryo-lamellae
into the wider cellular context. <br>
<b><br>
Join this webinar to:</b><o:p></o:p></p>
<p class="MsoNormal"> <o:p></o:p></p>
<ul style="margin-top:0cm" type="disc">
<li class="MsoNormal" style="mso-list:l0 level1 lfo1">Discover how Professor Zuber was able to obtain high-resolution reconstructions from CEMOVIS sections<o:p></o:p></li><li class="MsoNormal" style="mso-list:l0 level1 lfo1">See how the sections keep molecular structures intact in many regions despite damage from the technique<o:p></o:p></li><li class="MsoNormal" style="mso-list:l0 level1 lfo1">Learn how complementary techniques can help place cryo-lamellae in the wider cellular context<o:p></o:p></li></ul>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Thanks, and look forward to seeing some of you there,<o:p></o:p></p>
<p class="MsoNormal">Claire<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><b><span lang="EN-US" style="font-size:11.0pt;font-family:"Arial",sans-serif;mso-fareast-language:EN-GB">Claire Naylor, Ph.D (she/her/hers)<o:p></o:p></span></b></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:10.0pt;font-family:"Arial",sans-serif;mso-fareast-language:EN-GB">Regional Market Development EMEA<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:10.0pt;font-family:"Arial",sans-serif;mso-fareast-language:EN-GB"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:10.0pt;font-family:"Arial",sans-serif;mso-fareast-language:EN-GB">Thermo Fisher Scientific<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:10.0pt;font-family:"Arial",sans-serif;mso-fareast-language:EN-GB">Stafford House, 1 Boundary Park, Hemel Hempstead Industrial Estate | HP2 7GE | UK<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:10.0pt;font-family:"Arial",sans-serif;color:black;mso-fareast-language:EN-GB"><a href="mailto:Claire.naylor@thermofisher.com"><span style="color:#467886">Claire.naylor@thermofisher.com</span></a>
</span><span lang="EN-US" style="font-size:10.0pt;font-family:"Arial",sans-serif;mso-fareast-language:EN-GB">|
<a href="https://urldefense.com/v3/__http://www.thermofisher.com/__;!!Mih3wA!E9rycH--iBdXSFNPJ0e43fmdGy0NVe-sfVmmlIiz--DAd3UfKTpcr1Iq9dPgsfPcNUMvkKUlSjOiYw0tgrQXVw2ML_kLDug$"><span style="color:blue">www.thermofisher.com</span></a>
<span style="color:black"> </span>| Mobile: +44 (0)7353 153679<o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
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