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<p class="MsoNormal"><b><span style="font-size:14.0pt;font-family:"Arial",sans-serif">Post-doctoral Associate positions are immediately available in Tina Izard’s cell adhesion laboratory<o:p></o:p></span></b></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif">Join a dynamic structural biology group at the UF-Scripps, where we push the boundaries of molecular visualization and membrane biology. Our lab integrates cutting-edge cryoEM,
membrane biophysics, and infection/immunity research to redefine how receptors like integrins, GPCRs, and adhesion complexes are regulated. This position offers the opportunity to drive high-impact projects, publish in top journals, and grow your expertise
in method development and biological discovery. <o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
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<p class="MsoNormal"><b><span style="font-size:14.0pt;font-family:"Arial",sans-serif">About this opportunity<o:p></o:p></span></b></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif">Successful candidates will work in a cutting-edge research environment with new state-of-the-art facilities. The laboratory has outstanding cell biology, molecular biology, protein
expression, purification, biochemistry, cryogenic electron microscopy, and protein crystallography facilities. The laboratory has access to many exceptional Cores, facilitating basic research and drug development. The unique infrastructure includes the application
of unique chemical, genomic, proteomic, informatics, and high-throughput screening and engineering tools for discovering novel biomolecules.<o:p></o:p></span></p>
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<p class="MsoNormal"><b><span style="font-size:14.0pt;font-family:"Arial",sans-serif">CryoEM at UF-Scripps<o:p></o:p></span></b></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif">Tina Izard installed the first 300 kV cryo Atomic Resolution Microscope (cryoARM300) in the Americas (<a href="https://urldefense.com/v3/__https://www.youtube.com/watch?v=xdVxAN8xy1w&feature=youtu.be)__;!!Mih3wA!DDo1nFVbZw6S4jOXirodGuI4tfElR-MrFp5p5d3_XBSii1Ay4QH36lsh5mHbDg6_paW328YN-3_jmClnT1I$">https://www.youtube.com/watch?v=xdVxAN8xy1w&feature=youtu.be)</a>
and has plenty of microscope time dedicated to the post-doctoral associates. This state-of-the-art transmission electron microscope is a 300 kV high-resolution microscope capable of carrying out cryogenic electron microscopy studies by providing atomic resolution
for structural studies involving single particle analyses. The transmission electron microscope is equipped with a new and improved Gatan K3 direct electron detector camera with better DQE, a larger field of view (24 Megapixels – 5,760 x 4,092), and faster
(3.75 times that of the K2 camera). The direct detection devices are exquisitely sensitive, produce high signal-to-noise images, and are ideal for high-resolution studies.<o:p></o:p></span></p>
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<p class="MsoNormal"><b><span style="font-size:14.0pt;font-family:"Arial",sans-serif">X-ray crystallography at UF-Scripps<o:p></o:p></span></b></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif">The lab has access to SER-CAT beamlines at Sector 22 of the Advanced Photon Source, including modern insertion device lines (22-ID-D, variable wavelength, and 22-ID-E, fixed
wavelength) as well as a bending magnet line (22-BM) for macromolecular crystallography. These facilities are equipped with updated optics and detectors, and fall under current APS upgrades, ensuring high performance for structural biology projects.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif">The lab has access to a HighFlux X-ray diffraction system, specifically a Rigaku MicroMax-007 HF, a second-generation microfocus rotating anode generator, and a mar345 Image
Plate detector. An Osmic VariMax optics system and the Proteros Free Mounting System can be used to control the humidity and optimize diffraction characteristics, including resolution, mosaicity, anisotropy, and reduced X-ray background.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
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<p class="MsoNormal"><b><span style="font-size:14.0pt;font-family:"Arial",sans-serif">Intellectual environment<o:p></o:p></span></b></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif">UF-Scripps shares its Jupiter campus with the Max Planck Florida Institute for Neuroscience (MPFI), North America's only Max Planck Institute. MPFI is internationally recognized
for innovation in imaging and neuroscience, and its presence creates a unique, highly collaborative research environment. Postdocs benefit from joint seminars, shared facilities, interdisciplinary collaborations, and daily interaction with world-class scientists
across structural biology, chemical biology, and neuroscience. This close partnership expands opportunities for discovery and professional growth beyond what most academic campuses offer.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
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<p class="MsoNormal"><b><span style="font-size:14.0pt;font-family:"Arial",sans-serif">Why Jupiter, Florida?<o:p></o:p></span></b></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif">UF-Scripps is located in Jupiter, Florida, a vibrant coastal community in Palm Beach County. Jupiter offers an outstanding quality of life with year-round sunshine, beautiful
beaches, outdoor recreation, and a safe, family-friendly atmosphere. The area combines the advantages of a relaxed lifestyle with proximity to Miami and Orlando for cultural and professional opportunities. Florida has no state income tax, making post-doctoral
salaries go further, and the cost of living in northern Palm Beach County is favorable compared to many other significant research hubs. The campus itself is part of a growing biotech corridor that includes Max Planck Florida, providing an interdisciplinary,
collaborative environment with cutting-edge science in an exceptional location.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif;color:black"><o:p> </o:p></span></p>
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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:black">--<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:9.0pt;font-family:Helvetica;color:black">Dr. T. Izard <br>
Professor <br>
Cell Adhesion Laboratory <o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:9.0pt;font-family:Helvetica;color:black">Member, Scientific Advisory Group, UF ICBR EM Core</span><span style="font-size:9.0pt;font-family:Helvetica;color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:9.0pt;font-family:Helvetica;color:black">Board Member, SER-CAT, Advanced Photon Source, Argonne National Laboratory</span><span style="font-size:9.0pt;font-family:Helvetica;color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:9.0pt;font-family:Helvetica;color:black"></span><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:black"> <o:p></o:p></span></p>
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