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<p class="MsoNormal">Hi all, <o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">We are looking for a postdoc with experience using cryoFIB-SEM and cryo-electron tomography to lead research into the in situ structural biology of the human immune system.
<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">This advert is for an ERC-funded 3-year position using our new Hydra Bio cryoFIB-SEM, currently being installed in Bristol, to prepare samples for structural biology using cryo-electron tomography and cryoEM. The successful candidate will
work with immunologists and synthetic biologists to gain a greater understanding of phagocytosis, with the aim to develop new immunotherapeutics able to mimic, inhibit, induce or otherwise modulate the molecular orchestra underlying phagocytosis.<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Please see the advert <a href="https://urldefense.com/v3/__https://www.bristol.ac.uk/jobs/find/details/?nPostingId=194896&nPostingTargetId=378062&id=Q50FK026203F3VBQBV7V77V83&LG=UK&languageSelect=UK&mask=newuobext__;!!Mih3wA!FO9mHPA0eTUsf0UU9N-mGh_0dm4osN2f2QkNtKQ-k_eDJy0unw6K_ZJeqsge0E3T6cWqGL4U1nB899mtnyQm2vU$">
here</a> or at the link below:<o:p></o:p></p>
<p class="MsoNormal"><a href="https://urldefense.com/v3/__https://www.bristol.ac.uk/jobs/find/details/?nPostingId=194896&nPostingTargetId=378062&id=Q50FK026203F3VBQBV7V77V83&LG=UK&languageSelect=UK&mask=newuobext__;!!Mih3wA!FO9mHPA0eTUsf0UU9N-mGh_0dm4osN2f2QkNtKQ-k_eDJy0unw6K_ZJeqsge0E3T6cWqGL4U1nB899mtnyQm2vU$">https://www.bristol.ac.uk/jobs/find/details/?nPostingId=194896&nPostingTargetId=378062&id=Q50FK026203F3VBQBV7V77V83&LG=UK&languageSelect=UK&mask=newuobext</a><o:p></o:p></p>
<p class="MsoNormal"><b><o:p> </o:p></b></p>
<p class="MsoNormal"><b>Closing date is 29<sup>th</sup> July 2025<o:p></o:p></b></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">The Sharp lab is based at the University of Bristol, UK, where we combine structural and synthetic biology to understand and control the human immune system. We are a highly collaborative lab with a track record of turning new structures
into therapeutic candidates, as well as excellent links with industry. Please see our website for more information on the Sharp lab:
<a href="https://urldefense.com/v3/__https://sharplab.uk/__;!!Mih3wA!FO9mHPA0eTUsf0UU9N-mGh_0dm4osN2f2QkNtKQ-k_eDJy0unw6K_ZJeqsge0E3T6cWqGL4U1nB899mt5vctCNQ$">https://sharplab.uk/</a><o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Feel free to contact me with informal enquiries: <a href="mailto:t.sharp@bristol.ac.uk">
t.sharp@bristol.ac.uk</a><o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
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<p class="MsoNormal" style="background:white"><span style="font-family:"Calibri",sans-serif;color:black;background:white;mso-ligatures:none;mso-fareast-language:EN-GB">All the best,<o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span style="font-family:"Calibri",sans-serif;color:black;background:white;mso-ligatures:none;mso-fareast-language:EN-GB"><o:p> </o:p></span></p>
<p class="MsoNormal" style="background:white"><span style="font-family:"Calibri",sans-serif;color:black;background:white;mso-ligatures:none;mso-fareast-language:EN-GB">Thom<o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span style="font-family:"Calibri",sans-serif;color:black;background:white;mso-ligatures:none;mso-fareast-language:EN-GB"><o:p> </o:p></span></p>
<p class="MsoNormal" style="background:white"><b><span style="font-family:"Calibri",sans-serif;color:#3A3A3A;background:white;mso-ligatures:none">Dr. Thomas H. Sharp</span></b><b><span style="font-size:12.0pt;font-family:"Calibri",sans-serif;color:#3A3A3A;background:white;mso-ligatures:none"><br>
</span></b><span style="font-size:10.0pt;font-family:"Calibri",sans-serif;color:#747474;background:white;mso-ligatures:none">Associate Professor</span><b><span style="font-size:12.0pt;font-family:"Calibri",sans-serif;color:#3A3A3A;background:white;mso-ligatures:none"><br>
</span></b><span style="font-size:10.0pt;font-family:"Calibri",sans-serif;color:#747474;background:white;mso-ligatures:none">Room C101b, School of Biochemistry,
</span><span style="font-size:10.0pt;font-family:"Calibri",sans-serif;color:#747474;mso-ligatures:none">University of Bristol, BS8 1TD, UK<br>
Tel: +44 (0)117 455 2024<br>
Email: <a href="mailto:t.sharp@bristol.ac.uk"><span style="color:#467886">t.sharp@bristol.ac.uk</span></a><br>
</span><span style="font-size:12.0pt;color:black;mso-ligatures:none"><img border="0" width="166" height="50" style="width:1.7291in;height:.5208in" id="Picture_x0020_1" src="cid:image001.png@01DBF0E8.B5948510" alt="signature_2333760797"></span><o:p></o:p></p>
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