<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:x="urn:schemas-microsoft-com:office:excel" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40">
<head>
<meta http-equiv="Content-Type" content="text/html; charset=Windows-1252">
<meta name="Generator" content="Microsoft Word 15 (filtered medium)">
<style><!--
/* Font Definitions */
@font-face
{font-family:"Cambria Math";
panose-1:2 4 5 3 5 4 6 3 2 4;}
@font-face
{font-family:Aptos;
panose-1:2 11 0 4 2 2 2 2 2 4;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{margin:0cm;
font-size:11.0pt;
font-family:"Aptos",sans-serif;
mso-ligatures:standardcontextual;
mso-fareast-language:EN-US;}
a:link, span.MsoHyperlink
{mso-style-priority:99;
color:#467886;
text-decoration:underline;}
span.EmailStyle17
{mso-style-type:personal-compose;
font-family:"Aptos",sans-serif;
color:windowtext;}
.MsoChpDefault
{mso-style-type:export-only;
font-size:11.0pt;
mso-fareast-language:EN-US;}
@page WordSection1
{size:612.0pt 792.0pt;
margin:72.0pt 72.0pt 72.0pt 72.0pt;}
div.WordSection1
{page:WordSection1;}
/* List Definitions */
@list l0
{mso-list-id:883710304;
mso-list-template-ids:19289718;}
@list l0:level1
{mso-level-number-format:bullet;
mso-level-text:\F0B7 ;
mso-level-tab-stop:36.0pt;
mso-level-number-position:left;
text-indent:-18.0pt;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l0:level2
{mso-level-number-format:bullet;
mso-level-text:\F0B7 ;
mso-level-tab-stop:72.0pt;
mso-level-number-position:left;
text-indent:-18.0pt;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l0:level3
{mso-level-number-format:bullet;
mso-level-text:\F0B7 ;
mso-level-tab-stop:108.0pt;
mso-level-number-position:left;
text-indent:-18.0pt;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l0:level4
{mso-level-number-format:bullet;
mso-level-text:\F0B7 ;
mso-level-tab-stop:144.0pt;
mso-level-number-position:left;
text-indent:-18.0pt;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l0:level5
{mso-level-number-format:bullet;
mso-level-text:\F0B7 ;
mso-level-tab-stop:180.0pt;
mso-level-number-position:left;
text-indent:-18.0pt;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l0:level6
{mso-level-number-format:bullet;
mso-level-text:\F0B7 ;
mso-level-tab-stop:216.0pt;
mso-level-number-position:left;
text-indent:-18.0pt;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l0:level7
{mso-level-number-format:bullet;
mso-level-text:\F0B7 ;
mso-level-tab-stop:252.0pt;
mso-level-number-position:left;
text-indent:-18.0pt;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l0:level8
{mso-level-number-format:bullet;
mso-level-text:\F0B7 ;
mso-level-tab-stop:288.0pt;
mso-level-number-position:left;
text-indent:-18.0pt;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l0:level9
{mso-level-number-format:bullet;
mso-level-text:\F0B7 ;
mso-level-tab-stop:324.0pt;
mso-level-number-position:left;
text-indent:-18.0pt;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
ol
{margin-bottom:0cm;}
ul
{margin-bottom:0cm;}
--></style><!--[if gte mso 9]><xml>
<o:shapedefaults v:ext="edit" spidmax="1026" />
</xml><![endif]--><!--[if gte mso 9]><xml>
<o:shapelayout v:ext="edit">
<o:idmap v:ext="edit" data="1" />
</o:shapelayout></xml><![endif]-->
</head>
<body lang="EN-GB" link="#467886" vlink="#96607D" style="word-wrap:break-word">
<div class="WordSection1">
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="color:#212121;mso-ligatures:none;mso-fareast-language:EN-GB">Hi everyone,<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="color:#212121;mso-ligatures:none;mso-fareast-language:EN-GB">We’re excited to announce that applications are now open for the upcoming course <b>“Introduction to Single-Particle
Cryo-EM,”</b> taking place <b>1–4 September 2025</b> at the <b>Astbury Biostructure Laboratory, University of Leeds</b>.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="color:#212121;mso-ligatures:none;mso-fareast-language:EN-GB">This course is part of the community-led national cryo-EM training programme funded by Wellcome and the MRC,
and is aimed at PhD students and postdocs with little or no prior experience in single-particle cryo-EM.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="color:#212121;mso-ligatures:none;mso-fareast-language:EN-GB">Over four days, participants will gain a combination of theory and hands-on training, including:<o:p></o:p></span></p>
<ul type="disc">
<li class="MsoNormal" style="color:#212121;mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;mso-list:l0 level1 lfo1">
<span style="mso-ligatures:none;mso-fareast-language:EN-GB">Negative stain and cryo-EM sample preparation (including time-resolved workflows), room temperature TEM<o:p></o:p></span></li><li class="MsoNormal" style="color:#212121;mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;mso-list:l0 level1 lfo1">
<span style="mso-ligatures:none;mso-fareast-language:EN-GB">Grid screening and data collection using the Titan Krios microscope<o:p></o:p></span></li><li class="MsoNormal" style="color:#212121;mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;mso-list:l0 level1 lfo1">
<span style="mso-ligatures:none;mso-fareast-language:EN-GB">A live demonstration of data processing using RELION<o:p></o:p></span></li></ul>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="color:#212121;mso-ligatures:none;mso-fareast-language:EN-GB">The course is <b>free of charge</b>. Accommodation and meals are provided, and we will reimburse travel
expenses up to £250.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="color:#212121;mso-ligatures:none;mso-fareast-language:EN-GB">Places are limited.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="color:#212121;mso-ligatures:none;mso-fareast-language:EN-GB">For more information and to apply, please visit: <a href="https://urldefense.com/v3/__https://astbury.leeds.ac.uk/facilities/wellcome-mrc-training-in-cryoem/introduction-to-single-particle-cryo-em-september-2025/__;!!Mih3wA!BRaZtZeJrm1X80tRdCwOvCpcgV8OTkjsgWZdUc9DJWGwRHoFUK_fBHNNBykjEI6scIyOV6dJyoXK8MzwrYtvd6QzgYM$" title="https://astbury.leeds.ac.uk/facilities/wellcome-mrc-training-in-cryoem/introduction-to-single-particle-cryo-em-september-2025/"><span style="color:#96607D">https://astbury.leeds.ac.uk/facilities/wellcome-mrc-training-in-cryoem/introduction-to-single-particle-cryo-em-september-2025/</span></a><o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="color:#212121;mso-ligatures:none;mso-fareast-language:EN-GB">If you have any questions, feel free to contact us at <b><a href="mailto:EMcourses@leeds.ac.uk" title="mailto:EMcourses@leeds.ac.uk"><span style="color:#96607D;font-weight:normal">EMcourses@leeds.ac.uk</span></a></b>.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="color:#212121;mso-ligatures:none;mso-fareast-language:EN-GB">Best wishes,<br>
Oksana (University of Leeds), Emma (University of Leicester), Christos (eBIC, Diamond Light Source), James (University of Glasgow), Mark (Birkbeck College)<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><i><span style="color:#212121;mso-ligatures:none;mso-fareast-language:EN-GB">Wellcome Trust and MRC Cryo-EM Training Grant (218785/Z/19/Z)</span></i><span style="color:#212121;mso-ligatures:none;mso-fareast-language:EN-GB"><br>
<a href="https://urldefense.com/v3/__https://astbury.leeds.ac.uk/facilities/wellcome-mrc-training-in-cryoem/training-courses-in-cryo-em/__;!!Mih3wA!BRaZtZeJrm1X80tRdCwOvCpcgV8OTkjsgWZdUc9DJWGwRHoFUK_fBHNNBykjEI6scIyOV6dJyoXK8MzwrYtv-iDSFUM$" target="_new" title="https://astbury.leeds.ac.uk/facilities/wellcome-mrc-training-in-cryoem/training-courses-in-cryo-em/"><span style="color:#96607D">https://astbury.leeds.ac.uk/facilities/wellcome-mrc-training-in-cryoem/training-courses-in-cryo-em/</span></a><o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
</div>
</body>
</html>