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<p class="MsoNormal"><span style="color:#212121">Dear Colleagues,<o:p></o:p></span></p>
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<span style="color:#212121"><o:p> </o:p></span></p>
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<span style="color:#212121">The<span class="apple-converted-space"> </span><a href="https://urldefense.com/v3/__https://www.zunlongke-lab.org/__;!!Mih3wA!ByBF6afNNTGfxraHclCr9gmu3DHtyYI8D8RsCW7_80iab4k0684yLHQR8PyN-aLRIyoI76FTwdwPK8HMSv_6gs54gPwEbWQ$" title="https://www.zunlongke-lab.org/"><span style="color:#96607D">Ke Lab</span></a><span class="apple-converted-space"> </span>at the University
of Texas at Austin, Texas seeks to recruit a highly motivated, ambitious Postdoc Fellow in virology and structural biology. Please see more details here:<o:p></o:p></span></p>
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<span style="color:#212121"><a href="https://urldefense.com/v3/__https://utaustin.wd1.myworkdayjobs.com/UTstaff/job/AUSTIN-TX/Postdoctoral-Fellow_R_00039070__;!!Mih3wA!ByBF6afNNTGfxraHclCr9gmu3DHtyYI8D8RsCW7_80iab4k0684yLHQR8PyN-aLRIyoI76FTwdwPK8HMSv_6gs54UoQABMA$" title="https://utaustin.wd1.myworkdayjobs.com/UTstaff/job/AUSTIN-TX/Postdoctoral-Fellow_R_00039070"><span style="color:#96607D">https://utaustin.wd1.myworkdayjobs.com/UTstaff/job/AUSTIN-TX/Postdoctoral-Fellow_R_00039070</span></a><o:p></o:p></span></p>
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<span style="color:#212121"> <o:p></o:p></span></p>
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<b><span style="color:#212121">About the postdoc position:</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<span style="color:#212121">To work within the Laboratory of Dr. Zunlong Ke at the Department of Molecular Biosciences, the University of Texas at Austin. This postdoc position is fully funded by Cancer Prevention and Research Institute of Texas and the Welch
Foundation. The aim for this position is to investigate cancer-causing viruses and their interactions with hosts using a spectrum of structural biology techniques. We will take advantage of the state-of-the-art cryo-electron microscopy (cryo-EM), cryo-electron
tomography (cryo-ET), cryo-correlative microscopy (cryo-CLEM), cryo-FIB milling, coupled with functional assays to dissect the molecular mechanisms of cancer-causing viruses.<o:p></o:p></span></p>
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<span style="color:#212121"> <o:p></o:p></span></p>
<p class="MsoNormal" style="caret-color: rgb(33, 33, 33);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-stroke-width: 0px;word-spacing:0px">
<span style="color:#212121">Examples of my previous work (including leading and contributing) on<span class="apple-converted-space"> </span><b>enveloped viruses using cryo-EM, cryo-ET, and subtomogram averaging</b>:<span class="apple-converted-space"> </span><o:p></o:p></span></p>
<p class="MsoNormal" style="caret-color: rgb(33, 33, 33);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-stroke-width: 0px;word-spacing:0px">
<span style="color:#212121"><a href="https://urldefense.com/v3/__https://www.nature.com/articles/s41586-020-2665-2__;!!Mih3wA!ByBF6afNNTGfxraHclCr9gmu3DHtyYI8D8RsCW7_80iab4k0684yLHQR8PyN-aLRIyoI76FTwdwPK8HMSv_6gs54oQqVUUE$" title="https://www.nature.com/articles/s41586-020-2665-2"><span style="color:#0078D7">SARS-CoV-2 Spike</span></a><span class="apple-converted-space"> </span>and<span class="apple-converted-space"> </span><a href="https://urldefense.com/v3/__https://www.embopress.org/doi/full/10.1038/s44318-024-00303-1__;!!Mih3wA!ByBF6afNNTGfxraHclCr9gmu3DHtyYI8D8RsCW7_80iab4k0684yLHQR8PyN-aLRIyoI76FTwdwPK8HMSv_6gs544sr1d5M$" title="https://www.embopress.org/doi/full/10.1038/s44318-024-00303-1"><span style="color:#96607D">SARS-CoV-2
variants </span></a>(<i>Nature</i>, EMBO J, Postdoc with John Briggs),<span class="apple-converted-space"> </span><a href="https://urldefense.com/v3/__https://www.nature.com/articles/s41467-018-04058-2__;!!Mih3wA!ByBF6afNNTGfxraHclCr9gmu3DHtyYI8D8RsCW7_80iab4k0684yLHQR8PyN-aLRIyoI76FTwdwPK8HMSv_6gs54GrrAT-k$" title="https://www.nature.com/articles/s41467-018-04058-2"><span style="color:#0078D7">Measles
virus Matrix and Fusion glycoprotein</span></a> and<span class="apple-converted-space"> </span><a href="https://urldefense.com/v3/__https://www.mdpi.com/1999-4915/10/8/446__;!!Mih3wA!ByBF6afNNTGfxraHclCr9gmu3DHtyYI8D8RsCW7_80iab4k0684yLHQR8PyN-aLRIyoI76FTwdwPK8HMSv_6gs54guUkmGk$" title="https://www.mdpi.com/1999-4915/10/8/446"><span style="color:#0078D7">RSV morphology and assembly</span></a>(<i>Nature
Comm</i>, Viruses, PhD with Elizabeth Wright)<o:p></o:p></span></p>
<p class="MsoNormal" style="caret-color: rgb(33, 33, 33);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-stroke-width: 0px;word-spacing:0px">
<span style="color:#212121"><a href="https://urldefense.com/v3/__https://www.nature.com/articles/nprot.2016.168__;!!Mih3wA!ByBF6afNNTGfxraHclCr9gmu3DHtyYI8D8RsCW7_80iab4k0684yLHQR8PyN-aLRIyoI76FTwdwPK8HMSv_6gs54uLBWCQ0$" title="https://www.nature.com/articles/nprot.2016.168"><span style="color:#0078D7">Cryo-CLEM of infected/transfected cells</span></a><span class="apple-converted-space"> </span>and<span class="apple-converted-space"> </span><a href="https://urldefense.com/v3/__https://pubmed.ncbi.nlm.nih.gov/26069287/__;!!Mih3wA!ByBF6afNNTGfxraHclCr9gmu3DHtyYI8D8RsCW7_80iab4k0684yLHQR8PyN-aLRIyoI76FTwdwPK8HMSv_6gs54GdlsvUM$" title="https://pubmed.ncbi.nlm.nih.gov/26069287/"><span style="color:#0078D7">Immunogold
labeling for cryo-ET</span></a>: with Elizabeth Wright (during PhD)<o:p></o:p></span></p>
<p class="MsoNormal" style="caret-color: rgb(33, 33, 33);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-stroke-width: 0px;word-spacing:0px">
<span style="color:#212121">Recently, our collaborative work with Daniel Leahy at UT Austin on EGFR full-length by cryo-ET is out here at<span class="apple-converted-space"> </span><a href="https://urldefense.com/v3/__https://pubmed.ncbi.nlm.nih.gov/39651119/__;!!Mih3wA!ByBF6afNNTGfxraHclCr9gmu3DHtyYI8D8RsCW7_80iab4k0684yLHQR8PyN-aLRIyoI76FTwdwPK8HMSv_6gs54imzYR9E$" title="https://pubmed.ncbi.nlm.nih.gov/39651119/"><span style="color:#96607D">bioRxiv</span></a>.<o:p></o:p></span></p>
<p class="MsoNormal" style="caret-color: rgb(33, 33, 33);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-stroke-width: 0px;word-spacing:0px">
<span style="color:#212121"> <o:p></o:p></span></p>
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<b><span style="color:#212121">About the cryo-EM and cryo-ET facility at UT Austin:</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<span style="color:#212121">The<span class="apple-converted-space"> </span><a href="https://urldefense.com/v3/__https://structuralbiology.cns.utexas.edu/*/__;Iw!!Mih3wA!ByBF6afNNTGfxraHclCr9gmu3DHtyYI8D8RsCW7_80iab4k0684yLHQR8PyN-aLRIyoI76FTwdwPK8HMSv_6gs54bfS96gs$" title="https://structuralbiology.cns.utexas.edu/#/"><span style="color:#96607D">Sauer Structural Biology Laboratory</span></a><span class="apple-converted-space"> </span>currently
hosts a Titan Krios equipped with Gatan K3 camera with energy filter, a Talos Glacios with Falcon 4 camera, a few lower-voltage TEM for negative staining, and multiple grid plunge freezing apparatus. The facility is a welcoming environment and is supported
by extremely talented personnel.<o:p></o:p></span></p>
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<span style="color:#212121"> <o:p></o:p></span></p>
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<span style="color:#212121">The University is dedicated to expanding the cryo-EM and cryo-ET capacity. We recently purchased the following equipment and are expected to be installed this Fall:<o:p></o:p></span></p>
<ul style="margin-top:0in;caret-color: rgb(33, 33, 33);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-stroke-width: 0px;word-spacing:0px" type="disc">
<li class="MsoListParagraph" style="color:#212121;margin-top:0in;margin-bottom:0in;mso-list:l0 level1 lfo3">
An Aquilos 2 cryo-FIB/SEM, equipped with cryo-lift out and METEOR (Delmic) internal fluorescence microscope<o:p></o:p></li><li class="MsoListParagraph" style="color:#212121;margin-top:0in;margin-bottom:0in;mso-list:l0 level1 lfo3">
A STELLARIS 5 Cryo Confocal Light Microscope for cryo-CLEM imaging workflow<o:p></o:p></li><li class="MsoListParagraph" style="color:#212121;margin-top:0in;margin-bottom:0in;mso-list:l0 level1 lfo3">
A high-pressure freezer for thicker specimens<o:p></o:p></li><li class="MsoListParagraph" style="color:#212121;margin-top:0in;margin-bottom:0in;mso-list:l0 level1 lfo3">
A Leica GP2 for single-sided blotting of cellular materials and beyond<o:p></o:p></li></ul>
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<span style="color:#212121">With the completion of the renovation, the facility will be operated at BSL2 level from sample preparation to cryo-imaging.<o:p></o:p></span></p>
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<span style="color:#212121"> <o:p></o:p></span></p>
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<b><span style="color:#212121">About the Department, the University, and Austin:</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<span style="color:#212121">The Department of Molecular Biosciences hosts around 60 faculty with diverse research directions. The department is a collaborative environment with a strong group of structural biologists. The University of Texas at Austin is a
dynamic and vivid campus in the center of Austin, Texas.<span class="apple-converted-space"> </span>Known as the live music capital of the world, Austin is rapidly growing in recent years while maintaining the college town vibe.<o:p></o:p></span></p>
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<span style="color:#212121"> <o:p></o:p></span></p>
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<b><span style="color:#212121">How to apply:</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<span style="color:#212121">Successful postdoc applicants will hold a Ph.D. in a relevant area (e.g. virology, structural biology, biophysics) and have a strong track record of accomplishment in virology or structural biology.<o:p></o:p></span></p>
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<span style="color:#212121"> <o:p></o:p></span></p>
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<span style="color:#212121">Please submit your complete application documents, containing a cover letter describing your interests in my laboratory, your CV, and contact information for 3 references. Please apply here:<o:p></o:p></span></p>
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<span style="color:#212121"><a href="https://urldefense.com/v3/__https://utaustin.wd1.myworkdayjobs.com/UTstaff/job/AUSTIN-TX/Postdoctoral-Fellow_R_00039070__;!!Mih3wA!ByBF6afNNTGfxraHclCr9gmu3DHtyYI8D8RsCW7_80iab4k0684yLHQR8PyN-aLRIyoI76FTwdwPK8HMSv_6gs54UoQABMA$" title="https://utaustin.wd1.myworkdayjobs.com/UTstaff/job/AUSTIN-TX/Postdoctoral-Fellow_R_00039070"><span style="color:#96607D">https://utaustin.wd1.myworkdayjobs.com/UTstaff/job/AUSTIN-TX/Postdoctoral-Fellow_R_00039070</span></a><o:p></o:p></span></p>
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<span style="color:#212121">Alternatively, you can email me directly. The position is available immediately.<o:p></o:p></span></p>
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<span style="color:#212121"> <o:p></o:p></span></p>
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<span style="color:#212121">We are also actively recruiting perspective PhD students and post-bac research technicians. Informal inquiries are encouraged and can email me directly at<span class="apple-converted-space"> </span><a href="mailto:zunlong.ke@austin.utexas.edu" title="mailto:zunlong.ke@austin.utexas.edu"><span style="color:#0078D7">zunlong.ke@austin.utexas.edu</span></a>.<o:p></o:p></span></p>
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<span style="color:#212121"> <o:p></o:p></span></p>
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<span style="color:#212121">Best Regards,<o:p></o:p></span></p>
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<span style="color:#212121"> <o:p></o:p></span></p>
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<b><span style="color:black">Zunlong Ke, PhD</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<span style="color:#5A6D76">Assistant Professor</span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="color:#5A6D76">CPRIT Scholar</span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="color:#5A6D76">Department of Molecular Biosciences</span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="color:#BF5705">The University of Texas at Austin</span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="color:#212121"><a href="https://urldefense.com/v3/__https://www.zunlongke-lab.org/__;!!Mih3wA!ByBF6afNNTGfxraHclCr9gmu3DHtyYI8D8RsCW7_80iab4k0684yLHQR8PyN-aLRIyoI76FTwdwPK8HMSv_6gs54gPwEbWQ$" title="https://www.zunlongke-lab.org/"><span style="color:#96607D">zunlongke-lab.org</span></a><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
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