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<div class="WordSection1">
<p class="paragraph" style="margin:0cm;vertical-align:baseline"><span class="normaltextrun"><span lang="EN-US" style="font-size:11.0pt;color:black">Dear Structural Biology Community,</span></span><span class="eop"><span style="font-size:11.0pt;color:black"> <o:p></o:p></span></span></p>
<p class="paragraph" style="margin:0cm;vertical-align:baseline"><span style="font-size:9.0pt;font-family:"Segoe UI",sans-serif"><o:p> </o:p></span></p>
<p class="paragraph" style="margin:0cm;vertical-align:baseline;-webkit-user-drag: none;-webkit-user-select: text;overflow-wrap: break-word;white-space:pre-wrap;-webkit-nbsp-mode: normal !important">
<span class="normaltextrun"><span lang="EN-US" style="font-size:11.0pt;color:black">We are delighted to announce that registration is now open for online participation in the
<b>‘Wellcome-MRC Cryo-EM in Structural Biology 2025’ </b>course, which will be held
<b>in person at two venues</b>—<b>Diamond Light Source (Oxford)</b> and <b>The Astbury Centre (Leeds)</b>—with lectures broadcast online via Zoom.</span></span><span class="eop"><span style="font-size:11.0pt;color:black"> </span></span><span style="font-size:9.0pt;font-family:"Segoe UI",sans-serif"><o:p></o:p></span></p>
<p class="paragraph" style="mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:0cm;margin-left:54.0pt;text-indent:0cm;mso-list:l0 level1 lfo1;vertical-align:baseline;-webkit-user-drag: none;-webkit-user-select: text;overflow-wrap: break-word;white-space:pre-wrap;-webkit-nbsp-mode: normal !important">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span class="normaltextrun"><b><span lang="EN-US" style="font-size:11.0pt;color:black">Course Dates:</span></b></span><span class="normaltextrun"><span lang="EN-US" style="font-size:11.0pt;color:black"> 3rd - 7th March 2025</span></span><span class="eop"><span style="font-size:11.0pt;color:black"> </span></span><span style="font-size:11.0pt"><o:p></o:p></span></p>
<p class="paragraph" style="mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:0cm;margin-left:54.0pt;text-indent:0cm;mso-list:l1 level1 lfo2;vertical-align:baseline;-webkit-user-drag: none;-webkit-user-select: text;overflow-wrap: break-word;white-space:pre-wrap;-webkit-nbsp-mode: normal !important">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span class="normaltextrun"><b><span lang="EN-US" style="font-size:11.0pt;color:black">In-Person Applications:</span></b></span><span class="normaltextrun"><span lang="EN-US" style="font-size:11.0pt;color:black"> Applications
for in-person attendance are now closed.</span></span><span class="eop"><span style="font-size:11.0pt;color:black"> </span></span><span style="font-size:11.0pt"><o:p></o:p></span></p>
<p class="paragraph" style="mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:0cm;margin-left:54.0pt;text-indent:0cm;mso-list:l2 level1 lfo3;vertical-align:baseline;-webkit-user-drag: none;-webkit-user-select: text;overflow-wrap: break-word;white-space:pre-wrap;-webkit-nbsp-mode: normal !important">
<![if !supportLists]><span class="eop"><span style="font-size:10.0pt;font-family:Symbol"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="normaltextrun"><b><span lang="EN-US" style="font-size:11.0pt;color:black">Online Registration:</span></b></span><span class="normaltextrun"><span lang="EN-US" style="font-size:11.0pt;color:black"> Register </span></span><span style="font-size:11.0pt"><a href="https://urldefense.com/v3/__https://www.eventbrite.co.uk/e/wellcome-mrc-cryo-em-in-structural-biology-course-2025-tickets-1206626766139?aff=oddtdtcreator__;!!Mih3wA!Bx0FJModpsm128ZVfeRSRsJSommmpdiDi2rux3om3jDSlq9KkGZXmgH572ydJ1RpPH9zNFTDHIIdwmVBSVvHzpTlKQyT1VM$" target="_blank"><span class="normaltextrun"><span lang="EN-US" style="color:#467886">here</span></span></a></span><span class="normaltextrun"><span lang="EN-US" style="font-size:11.0pt;color:black"> via
Eventbrite for access to </span></span><span class="normaltextrun"><span lang="EN-US" style="font-size:11.0pt;color:black">the online lectures. Please ensure you select the 'Online (via Zoom)' ticket option.</span></span><span class="eop"><span style="font-size:11.0pt;color:black"> </span></span><span class="eop"><span style="font-size:11.0pt"><o:p></o:p></span></span></p>
<p class="paragraph" style="margin:0cm;vertical-align:baseline;-webkit-user-drag: none;-webkit-user-select: text;overflow-wrap: break-word;white-space:pre-wrap;-webkit-nbsp-mode: normal !important">
<span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="paragraph" style="margin:0cm;vertical-align:baseline"><span class="normaltextrun"><span style="font-size:11.0pt">This course, part of the cryo-EM
<b>Wellcome/MRC training programme</b>,<span style="color:black"> is designed to give researchers new to the field a solid foundation in cryo-EM.
</span>It includes lectures, demonstrations, and hands-on practicals covering fundamental topics in cryo-EM and cryo-ET, from sample preparation and the electron microscope, through to image formation and processing, reconstruction in SPA and cryo-ET, and model
building.</span></span><span class="eop"><span style="font-size:11.0pt"> </span></span><span style="font-size:11.0pt"><o:p></o:p></span></p>
<p class="paragraph" style="margin:0cm;vertical-align:baseline;-webkit-user-drag: none;-webkit-user-select: text;overflow-wrap: break-word;white-space:pre-wrap;-webkit-nbsp-mode: normal !important">
<span class="eop"><span style="font-size:11.0pt"> </span></span><span style="font-size:11.0pt"><o:p></o:p></span></p>
<p class="paragraph" style="margin:0cm;vertical-align:baseline;-webkit-user-drag: none;-webkit-user-select: text;overflow-wrap: break-word;white-space:pre-wrap;-webkit-nbsp-mode: normal !important">
<span class="normaltextrun"><span style="font-size:11.0pt">For more details, please visit the
</span></span><span style="font-size:11.0pt"><a href="https://urldefense.com/v3/__https://www.diamond.ac.uk/Instruments/Biological-Cryo-Imaging/eBIC/Training/Courses-and-workshops/2025-EventsCW/Cryogenic-Electron-Microscopy-in-Structural-Biology-2025.html__;!!Mih3wA!Bx0FJModpsm128ZVfeRSRsJSommmpdiDi2rux3om3jDSlq9KkGZXmgH572ydJ1RpPH9zNFTDHIIdwmVBSVvHzpTlCKjlH4w$" target="_blank"><span class="normaltextrun"><span style="color:#467886">event
webpage</span></span></a><span class="normaltextrun">.</span><span class="eop"> <o:p></o:p></span></span></p>
<p class="paragraph" style="margin:0cm;vertical-align:baseline"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="paragraph" style="margin:0cm;vertical-align:baseline;-webkit-user-drag: none;-webkit-user-select: text;overflow-wrap: break-word;white-space:pre-wrap;-webkit-nbsp-mode: normal !important">
<span class="normaltextrun"><span lang="EN-US" style="font-size:11.0pt;color:black">We look forward to seeing you online in March!</span></span><span class="eop"><span style="font-size:11.0pt;color:black"> <o:p></o:p></span></span></p>
<p class="paragraph" style="margin:0cm;vertical-align:baseline"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="paragraph" style="margin:0cm;vertical-align:baseline;-webkit-user-drag: none;-webkit-user-select: text;overflow-wrap: break-word;white-space:pre-wrap;-webkit-nbsp-mode: normal !important">
<span class="normaltextrun"><span lang="EN-US" style="font-size:11.0pt;color:black">Best wishes on behalf of all organisers,</span></span><span style="font-size:9.0pt;font-family:"Segoe UI",sans-serif"><o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
<div>
<div>
<p class="MsoNormal" style="background:white"><i><span style="font-size:14.0pt;font-family:"Arial",sans-serif;color:#002060;border:none windowtext 1.0pt;padding:0cm;mso-ligatures:none;mso-fareast-language:EN-GB">Lorna Malone </span></i><i><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#323E4F;border:none windowtext 1.0pt;padding:0cm;mso-ligatures:none;mso-fareast-language:EN-GB">(she/her)</span></i><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#323E4F;border:none windowtext 1.0pt;padding:0cm;mso-ligatures:none;mso-fareast-language:EN-GB"> </span><span style="font-size:12.0pt;font-family:"Segoe UI",sans-serif;color:black;mso-ligatures:none;mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><i><span style="font-size:13.5pt;font-family:"Arial",sans-serif;color:#002060;border:none windowtext 1.0pt;padding:0cm;mso-ligatures:none;mso-fareast-language:EN-GB">Electron Microscope Scientist & Training Coordinator</span></i><span style="font-size:12.0pt;font-family:"Segoe UI",sans-serif;color:black;mso-ligatures:none;mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#002060;border:none windowtext 1.0pt;padding:0cm;mso-ligatures:none;mso-fareast-language:EN-GB"> </span><span style="font-size:12.0pt;font-family:"Segoe UI",sans-serif;color:black;mso-ligatures:none;mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><i><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#002060;border:none windowtext 1.0pt;padding:0cm;mso-ligatures:none;mso-fareast-language:EN-GB">Phone: +44 1235 394182</span></i><span style="font-size:12.0pt;font-family:"Segoe UI",sans-serif;color:black;mso-ligatures:none;mso-fareast-language:EN-GB"><o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white"><b><u><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#002060;border:none windowtext 1.0pt;padding:0cm;mso-ligatures:none;mso-fareast-language:EN-GB"><a href="https://urldefense.com/v3/__https://www.diamond.ac.uk/Instruments/Biological-Cryo-Imaging/eBIC.html__;!!Mih3wA!Bx0FJModpsm128ZVfeRSRsJSommmpdiDi2rux3om3jDSlq9KkGZXmgH572ydJ1RpPH9zNFTDHIIdwmVBSVvHzpTlMu12C-I$" target="_blank"><span style="font-family:inherit;color:#002060">eBIC
website</span></a></span></u></b><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#002060;border:none windowtext 1.0pt;padding:0cm;mso-ligatures:none;mso-fareast-language:EN-GB"> </span><span style="font-size:12.0pt;font-family:"Segoe UI",sans-serif;color:black;mso-ligatures:none;mso-fareast-language:EN-GB"><o:p></o:p></span></p>
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