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<body lang="EN-US" link="blue" vlink="purple" style="word-wrap:break-word">
<div class="WordSection1">
<div>
<p class="MsoNormal"><b>The Role:</b> <o:p></o:p></p>
<p class="MsoNormal">The Mchaourab laboratory at Vanderbilt University in Nashville, TN is seeking an enthusiastic and diligent postdoctoral fellow to advance our longstanding research on neurotransmitter:sodium symporters (NSSs). This NIH-supported fellowship
focuses on evaluating mammalian serotonin transporter (SERT) using electron paramagnetic resonance (EPR) and cryo-EM techniques to explore its conformational dynamics. While experience with membrane transporters is highly valued, EPR and cryoEM training will
be provided. The project is central to collaborations with multiple institutions and integrates computational projects within our lab, requiring an individual with excellent communication skills. Salary will adhere to NIH standards and is negotiable based
on expertise. The preferred start date is April 2025, but it is flexible. <o:p></o:p></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif"> </span> <o:p></o:p></p>
<p class="MsoNormal"><b>Qualifications:</b> <o:p></o:p></p>
<ul style="margin-top:0in" type="disc">
<li class="MsoNormal" style="mso-list:l19 level1 lfo18">A Ph.D. in Biochemistry, Biophysics, or a related field. <o:p></o:p></li></ul>
<ul style="margin-top:0in" type="disc">
<li class="MsoNormal" style="mso-list:l0 level1 lfo19">Experience with expressing and purifying mammalian membrane proteins. <o:p></o:p></li></ul>
<ul style="margin-top:0in" type="disc">
<li class="MsoNormal" style="mso-list:l10 level1 lfo20">Experience in X-ray crystallography, cryo-EM, or EPR techniques is preferred. <o:p></o:p></li></ul>
<ul style="margin-top:0in" type="disc">
<li class="MsoNormal" style="mso-list:l15 level1 lfo21">Strong analytical skills and the ability to think deeply and critically about complex problems. <o:p></o:p></li></ul>
<ul style="margin-top:0in" type="disc">
<li class="MsoNormal" style="mso-list:l6 level1 lfo22">Excellent organizational skills and attention to detail. <o:p></o:p></li></ul>
<ul style="margin-top:0in" type="disc">
<li class="MsoNormal" style="mso-list:l20 level1 lfo23">Passion for scientific research and willingness to embrace new challenges. <o:p></o:p></li></ul>
<ul style="margin-top:0in" type="disc">
<li class="MsoNormal" style="mso-list:l12 level1 lfo24">Ability to work either independently or collaboratively. <o:p></o:p></li></ul>
<ul style="margin-top:0in" type="disc">
<li class="MsoNormal" style="mso-list:l1 level1 lfo25">Contributes to a positive work environment through actively participating in lab meetings and events. <o:p></o:p></li></ul>
<p class="MsoNormal"> <o:p></o:p></p>
<p class="MsoNormal"><b>About Us:</b> <o:p></o:p></p>
<p class="MsoNormal">The Mchaourab laboratory is highly interdisciplinary, utilizing a combination of structural, functional, and computational techniques to explore diverse topics, including conformational dynamics of active transporters and proteostasis in
zebrafish, among others. Our experimental expertise is in cryo-EM, EPR, and transport assays. While historically a fully experimental lab, we have embraced the recent revolution in protein structure prediction; we now integrate deep learning methods, such
as AlphaFold2, with experimental biophysical approaches to investigate the structure/dynamics/function in multiple classes of transporters. Training in the Mchaourab lab reflects the emerging paradigm of mechanistic structural biology at the interface of computation
and experimental sciences. <o:p></o:p></p>
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<p class="MsoNormal">The laboratory is located in the department of Molecular Physiology and Biophysics at Vanderbilt School of Medicine with access to state-of-the-art cores in high performance computing, cryo-EM, EPR, mass spectrometry and various biophysical
instrumentation. We are members of the newly inaugurated Center of Applied AI in Protein Dynamics (<a href="https://urldefense.com/v3/__https://www.vanderbilt.edu/ai-proteindynamics/__;!!Mih3wA!GyayxufgpfT1LInmL32RyIXiDmNXc2rUjOAGM-UqE7lAyZuX-ISk8grTe3qJjeawY2G7coxE9hH6vVaLDjuUM6pqh-VOM6x3$">https://www.vanderbilt.edu/ai-proteindynamics/</a>). <o:p></o:p></p>
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<p class="MsoNormal">If you are interested send CV and letters of recommendation to: Hassane S. Mchaourab, Ph. D., hassane.mchaourab@vanderbilt.edu <o:p></o:p></p>
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<p class="MsoNormal">At Vanderbilt University, we are intentional about and assume accountability for fostering advancement and respect for diversity, and inclusion for all students, faculty, and staff. We have created a community that celebrates differences
and lets individuality thrive. As part of this commitment, we actively value all aspects of diversity in our workplace and learning environments as we seek to take advantage of the rich backgrounds and abilities of everyone. <o:p></o:p></p>
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