<html><head><meta http-equiv="Content-Type" content="text/html; charset=us-ascii"></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class=""><div dir="auto" style="word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class=""><p class="MsoNormal">Dear cryo-EM enthusiasts, </p><p class="MsoNormal">The application to the upcoming 2025 Three-dimensional electron microscopy (<span class="" style="color: rgb(34, 34, 34);">3DEM) Gordon Research Seminar and Conference (GRS/GRC) is now open. </span><span class="" style="background-color: rgb(255, 255, 255); color: rgb(34, 34, 34);">The 2025 </span><font color="#222222" class="" style="background-color: rgb(255, 255, 255);"><span class="">3DEM GRS/GRC will be</span></font><span class="" style="background-color: rgb(255, 255, 255); color: rgb(34, 34, 34);"> held on Jun 15 - 20, 2025 at Grand Summit Hotel at Sunday River, Newry, Maine, USA. </span></p><p class="MsoNormal"><span style="font-family: Calibri, sans-serif; background-color: rgb(255, 255, 255);" class="">The 3DEM GRS, </span><span style="caret-color: rgb(34, 34, 34); color: rgb(34, 34, 34); background-color: rgb(255, 255, 255);" class="">co-chaired by Judy Huang and Sven Klumpe,</span><span style="font-family: Calibri, sans-serif; background-color: rgb(255, 255, 255);" class=""> is a one day event that offers a platform for early-career researchers to present their work, share cutting-edge ideas, and foster collaborations with peers in a supportive environment. The focus of the 2025 GRS will be novel approaches in Cryo-Electron Microscopy and Tomography, emphasizing recent advances in hardware and software that enable in situ structural biology. These developments have expanded opportunities to address complex biological questions using multimodal cryo-EM techniques which we will aim to highlight during the meeting. Through engaging sessions and mentorship, attendees can discuss challenges, share solutions, and build networks within the community. </span></p><p class="MsoNormal"><span lang="EN-GB" class="" style="color: rgb(34, 34, 34); background-color: white;">I will be charing the GRC and t</span><span class="" style="background-color: rgb(255, 255, 255); color: rgb(34, 34, 34);">he current program is available on: </span><a href="https://urldefense.com/v3/__https://www.grc.org/three-dimensional-electron-microscopy-conference/2025/__;!!Mih3wA!Bhd8X-wx5zC-5TH4HZIHM7VR-k0inTHlbq3045d4tGbB2p5-pkPpcsvOb8pT6B6c317h_RNR2cQ3l642cv14L1LkL70$" class="" style="background-color: rgb(255, 255, 255);">https://www.grc.org/three-dimensional-electron-microscopy-conference/2025/</a> </p><p class="MsoNormal"><span class="" style="background-color: rgb(255, 255, 255); color: rgb(34, 34, 34);">The 2025 edition will continue the tradition of highlighting cutting-edge method development in all aspects of high-resolution imaging of frozen-hydrated specimens with electron microscopy towards a structural and mechanistic understanding of complex biological systems. The scientific agenda will reflect advances in methods and instrumentation for specimen preparation </span><i class="" style="background-color: rgb(255, 255, 255); color: rgb(34, 34, 34);">in vitro </i><span class="" style="background-color: rgb(255, 255, 255); color: rgb(34, 34, 34);">and </span><i class="" style="background-color: rgb(255, 255, 255); color: rgb(34, 34, 34);">in situ</i><span class="" style="background-color: rgb(255, 255, 255); color: rgb(34, 34, 34);">, structural studies of dynamic macromolecules and their complex interactions with cryo-electron microscopy and tomography, three-dimensional multi-modal and correlative imaging, as well as computational approaches for data analysis, integration and interpretation, including AI-based methods. Following the tradition of 3DEM GRCs, two evening sessions are dedicated to presentations selected from posters at the meeting that accelerate exchange of emerging ideas and the discussion on the challenges and opportunities in the field. </span></p><p class="MsoNormal"><span lang="EN-GB" class="" style="color: rgb(34, 34, 34); background-color: white;">Applications to t</span><span lang="EN-GB" class="" style="color: rgb(34, 34, 34); background-color: white;">he GRC and GRS are independent, but we will do our best to accommodate as many GRS attendees in the GRC as well. </span><span style="background-color: rgb(255, 255, 255);" class=""><font face="Calibri, sans-serif" class="">We especially encourage trainees from underrepresented groups and countries to apply</font></span><font face="Calibri, sans-serif" class="">. Depending on the success of our fund raising efforts, we hope to be able to provide financial support to a number of early-career investigators for attending the meeting.</font></p><div style="orphans: 2; widows: 2;" class="">Looking forward to seeing you at the 2025 GRS/GRC, </div><div style="orphans: 2; widows: 2;" class=""><br class=""></div><div style="orphans: 2; widows: 2;" class="">Julia, Judy and Sven</div><div class="">
<div dir="auto" style="caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); letter-spacing: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration: none; word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class=""><div dir="auto" style="text-align: start; text-indent: 0px; word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class=""><div dir="auto" style="text-align: start; text-indent: 0px; word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class=""><div style="text-align: start; text-indent: 0px; word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class=""><div style="text-align: start; text-indent: 0px; word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class=""><div style="text-align: start; text-indent: 0px; word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class=""><div style="word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class=""><div style="caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); letter-spacing: normal; text-transform: none; white-space: normal; word-spacing: 0px; text-decoration: none; -webkit-text-stroke-width: 0px; font-family: Helvetica; font-size: 12px; font-style: normal; font-variant-caps: normal; font-weight: normal; text-align: start; text-indent: 0px;">________________________________________<br class=""><br class=""></div><div style="caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); letter-spacing: normal; text-transform: none; white-space: normal; word-spacing: 0px; text-decoration: none; -webkit-text-stroke-width: 0px; font-family: Helvetica; font-size: 12px; font-style: normal; font-variant-caps: normal; font-weight: normal; text-align: start; text-indent: 0px;">Julia Mahamid<br class="">Molecular Systems Biology Unit<br class="">European Molecular Biology Laboratory<br class="">Meyerhofstrasse 1<br class="">69117 Heidelberg<br class="">Germany<br class="">Phone: +49 (0)6221 387 8451</div><div style="text-align: start; text-indent: 0px;"><a href="mailto:julia.mahamid@embl.de" class="">julia.mahamid@embl.de</a><br class=""><a href="https://urldefense.com/v3/__https://www.embl.org/groups/mahamid/__;!!Mih3wA!Bhd8X-wx5zC-5TH4HZIHM7VR-k0inTHlbq3045d4tGbB2p5-pkPpcsvOb8pT6B6c317h_RNR2cQ3l642cv14Iory8Uw$">https://www.embl.org/groups/mahamid/</a></div><div style="text-align: start; text-indent: 0px;"><a href="https://urldefense.com/v3/__https://www.embl.org/research/units/molecular-systems-biology/__;!!Mih3wA!Bhd8X-wx5zC-5TH4HZIHM7VR-k0inTHlbq3045d4tGbB2p5-pkPpcsvOb8pT6B6c317h_RNR2cQ3l642cv14Ec43vGo$" class="">https://www.embl.org/research/units/molecular-systems-biology/</a></div></div></div></div></div></div></div></div>
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