<html><head><meta http-equiv="content-type" content="text/html; charset=utf-8"></head><body style="overflow-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;">Dear colleagues. <div><br></div><div>I would like to draw your attention to an exciting course we’re offering from February 9th - 14th, 2025 on in situ CLEM at room temp and in cryo!!</div><div><span style="font-family: Helvetica; color: rgb(26, 28, 26); orphans: 2; widows: 2;"><br></span></div><div><span style="font-family: Helvetica; color: rgb(26, 28, 26); orphans: 2; widows: 2;">The course is designed to equip participants with both practical, hands-on skills in Correlative Light and Electron Microscopy (CLEM) and a solid theoretical foundation. This advanced imaging modality enables researchers to precisely locate fluorescent proteins within cellular ultrastructures, a technique pioneered at the European Molecular Biology Laboratory (EMBL).</span></div><div><span style="font-family: Helvetica; color: rgb(26, 28, 26); orphans: 2; widows: 2;"><br></span></div><div><p style="color: rgb(26, 28, 26); line-height: 1.421; margin: var(--vf-stack-margin, 0) 0 1rem 0; font-variant-ligatures: normal; orphans: 2; widows: 2; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"><font face="Helvetica">Recognizing the increasing demand for in situ CLEM applications, the training is geared towards enabling attendees to create customized CLEM workflows to address their unique research questions and share this knowledge within their institutions. Our course delves into the specifics of this method, emphasising high-precision localization. In additon, it offers significant interaction with CLEM and EM experts, facilitating rich discussions and troubleshooting sessions. This ensures that participants not only learn the methodology but also gain insightful, actionable guidance to apply CLEM techniques effectively in their research endeavors.</font></p><p style="color: rgb(26, 28, 26); line-height: 1.421; margin: var(--vf-stack-margin, 0) 0 1rem 0; font-variant-ligatures: normal; orphans: 2; widows: 2; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"><span style="font-family: Helvetica;">For more information and for registration details please click here: </span></p><div style="display: block;"><div style="-webkit-user-select: all; -webkit-user-drag: element; display: inline-block;" class="apple-rich-link" draggable="true" role="link" data-url="https://www.embl.org/about/info/course-and-conference-office/events/lem25-01/"><a style="border-radius:10px;font-family:-apple-system, Helvetica, Arial, sans-serif;display:block;-webkit-user-select:none;width:300px;user-select:none;-webkit-user-modify:read-only;user-modify:read-only;overflow:hidden;text-decoration:none;" class="lp-rich-link" rel="nofollow" href="https://urldefense.com/v3/__https://www.embl.org/about/info/course-and-conference-office/events/lem25-01/__;!!Mih3wA!HFJ7AsAHiWY1uigd9D1PBQT1L0AqY7mXm0YRlavGJWHapc2TrIqxFVGNKjqjLNANwwEezE_1igeKc4oMVGsL$" dir="ltr" role="button" draggable="false" width="300"><table style="table-layout:fixed;border-collapse:collapse;width:300px;background-color:#E5E6E9;font-family:-apple-system, Helvetica, Arial, sans-serif;" class="lp-rich-link-emailBaseTable" cellpadding="0" cellspacing="0" border="0" width="300"><tbody><tr><td vertical-align="center" align="center"><img style="width:300px;filter:brightness(0.97);height:99px;" width="300" height="99" draggable="false" class="lp-rich-link-mediaImage" alt="LEM25-01_MS-Main-hero_banner_template_3000x1000-scaled.jpeg" src="cid:6E25F974-6449-4A2C-80AA-33C81A532C83"></td></tr><tr><td vertical-align="center"><table bgcolor="#E5E6E9" cellpadding="0" cellspacing="0" width="300" style="font-family:-apple-system, Helvetica, Arial, sans-serif;table-layout:fixed;background-color:rgba(229, 230, 233, 1);" class="lp-rich-link-captionBar"><tbody><tr><td style="padding:8px 0px 8px 0px;" class="lp-rich-link-captionBar-textStackItem"><div style="max-width:100%;margin:0px 16px 0px 16px;overflow:hidden;" class="lp-rich-link-captionBar-textStack"><div style="word-wrap:break-word;font-weight:500;font-size:12px;overflow:hidden;text-overflow:ellipsis;text-align:left;" class="lp-rich-link-captionBar-textStack-topCaption-leading"><a rel="nofollow" href="https://urldefense.com/v3/__https://www.embl.org/about/info/course-and-conference-office/events/lem25-01/__;!!Mih3wA!HFJ7AsAHiWY1uigd9D1PBQT1L0AqY7mXm0YRlavGJWHapc2TrIqxFVGNKjqjLNANwwEezE_1igeKc4oMVGsL$" style="text-decoration: none" draggable="false"><font color="#272727" style="color: rgba(0, 0, 0, 0.847059);">In situ CLEM at room temperature and in cryo</font></a></div><div style="word-wrap:break-word;font-weight:400;font-size:11px;overflow:hidden;text-overflow:ellipsis;text-align:left;" class="lp-rich-link-captionBar-textStack-bottomCaption-leading"><a rel="nofollow" href="https://urldefen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