<html>
<head>
<meta http-equiv="Content-Type" content="text/html; charset=iso-8859-1">
<style type="text/css" style="display:none;"> P {margin-top:0;margin-bottom:0;} </style>
</head>
<body dir="ltr">
<div class="elementToProof" style="font-family: Aptos, Aptos_EmbeddedFont, Aptos_MSFontService, Calibri, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
Dear cool people,</div>
<div class="elementToProof" style="font-family: Aptos, Aptos_EmbeddedFont, Aptos_MSFontService, Calibri, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
<br>
</div>
<div class="elementToProof" style="font-family: Aptos, Aptos_EmbeddedFont, Aptos_MSFontService, Calibri, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
The cryoEM map has been continually updated and many images have been added of PIs and instruments. Please email me with anything that's missing!</div>
<div class="elementToProof" style="font-family: Aptos, Aptos_EmbeddedFont, Aptos_MSFontService, Calibri, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
<br>
</div>
<div style="direction: ltr; line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt; font-family: Aptos, Aptos_EmbeddedFont, Aptos_MSFontService, Calibri, Helvetica, sans-serif; font-size: 12pt; color: rgb(17, 85, 204);" class="elementToProof">
<u><a href="https://urldefense.com/v3/__https://www.google.com/maps/d/viewer?mid=1eQ1r8BiDYfaK7D1S9EeFJEgkLggMyoaT&usp=sharing__;!!Mih3wA!GkK9ZBKg0A4XIR16X_r-0RoDsT6pezrkllFEChtW4XfGvOV4lc0qFETjfz2UbOH0AMhwNrF8v_LmGjCAOw$" id="OWA3e0697b9-0bec-9533-2a71-176bc68fa2ff" class="OWAAutoLink" style="color: rgb(17, 85, 204); margin-top: 0px; margin-bottom: 0px;" data-auth="NotApplicable">https://www.google.com/maps/d/viewer?mid=1eQ1r8BiDYfaK7D1S9EeFJEgkLggMyoaT&usp=sharing</a></u></div>
<div style="direction: ltr; line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt; font-family: Aptos, Aptos_EmbeddedFont, Aptos_MSFontService, Calibri, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);" class="elementToProof">
(short URL: <span style="color: rgb(17, 85, 204);"><u><a href="https://urldefense.com/v3/__https://tiny.cc/cryoem_map__;!!Mih3wA!GkK9ZBKg0A4XIR16X_r-0RoDsT6pezrkllFEChtW4XfGvOV4lc0qFETjfz2UbOH0AMhwNrF8v_KCtSS-ZA$" id="OWAb984437f-103e-94e1-0055-1d89dce3dae5" class="OWAAutoLink" style="color: rgb(17, 85, 204); margin-top: 0px; margin-bottom: 0px;" data-auth="NotApplicable">https://tiny.cc/cryoem_map</a></u></span>)</div>
<div class="elementToProof" style="font-family: Aptos, Aptos_EmbeddedFont, Aptos_MSFontService, Calibri, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
<br>
</div>
<div class="elementToProof" style="font-family: Aptos, Aptos_EmbeddedFont, Aptos_MSFontService, Calibri, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
On a related topic, I think the academic model of research is significantly inefficient: Excessive time is spent on grants/funding and bureaucracy instead of using our creativity and skills to pursue research and passions. While rare, private funding sometimes
creates positions that allow researchers to focus primarily on their research and passions. What positions in the cryoEM world provide such research freedom? Are there institutes interested in funding research positions? And how we increase the number of these
positions? (perhaps some readers might be interested in funding/contributing to them.) I'm interested in everyone's thoughts.</div>
<div class="elementToProof" style="font-family: Aptos, Aptos_EmbeddedFont, Aptos_MSFontService, Calibri, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
<br>
</div>
<div class="elementToProof" style="font-family: Aptos, Aptos_EmbeddedFont, Aptos_MSFontService, Calibri, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
Best wishes,</div>
<div class="elementToProof" style="font-family: Aptos, Aptos_EmbeddedFont, Aptos_MSFontService, Calibri, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
Alex Noble</div>
<div class="elementToProof" style="font-family: Aptos, Aptos_EmbeddedFont, Aptos_MSFontService, Calibri, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
SEMC</div>
<div id="appendonsend" style="color: inherit;"></div>
<div class="elementToProof" style="font-family: Aptos, Aptos_EmbeddedFont, Aptos_MSFontService, Calibri, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
<br>
</div>
<hr style="display: inline-block; width: 98%;">
<div id="divRplyFwdMsg" dir="ltr" style="color: inherit;"><span style="font-family: Calibri, sans-serif; font-size: 11pt; color: rgb(0, 0, 0);"><b>From:</b> Alex Noble <anoble@nysbc.org><br>
<b>Sent:</b> Monday, July 25, 2022 3:45 PM<br>
<b>To:</b> 3dem@ncmir.ucsd.edu <3dem@ncmir.ucsd.edu><br>
<b>Subject:</b> Map of Cryo-EM Worldwide</span>
<div> </div>
</div>
<div style="direction: ltr; font-size: 12pt; color: rgb(0, 0, 0);"><span style="background-color: rgb(255, 255, 255);">Dear cool people,</span></div>
<div style="background-color: rgb(255, 255, 255);">
<div style="direction: ltr; background-color: rgb(255, 255, 255); font-size: 12pt; color: rgb(0, 0, 0);">
<br>
</div>
<div style="direction: ltr; background-color: rgb(255, 255, 255); font-size: 12pt; color: rgb(0, 0, 0);">
The worldwide cryo-EM map has been significantly updated:</div>
<div style="direction: ltr; background-color: rgb(255, 255, 255); font-size: 12pt; color: rgb(0, 0, 0);">
<br>
</div>
<div style="background-color: rgb(255, 255, 255);">
<p style="direction: ltr; line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;" class="elementToProof">
<span style="font-family: Arial; font-size: 11pt; color: rgb(17, 85, 204);"><u><a href="https://urldefense.com/v3/__https://www.google.com/maps/d/viewer?mid=1eQ1r8BiDYfaK7D1S9EeFJEgkLggMyoaT&usp=sharing__;!!Mih3wA!GkK9ZBKg0A4XIR16X_r-0RoDsT6pezrkllFEChtW4XfGvOV4lc0qFETjfz2UbOH0AMhwNrF8v_LmGjCAOw$" id="OWA2a157640-b59c-c0fc-5fac-579b941a394b" class="OWAAutoLink" style="color: rgb(17, 85, 204); margin-top: 0px; margin-bottom: 0px;" data-auth="NotApplicable">https://www.google.com/maps/d/viewer?mid=1eQ1r8BiDYfaK7D1S9EeFJEgkLggMyoaT&usp=sharing</a></u></span></p>
<p style="direction: ltr; line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;" class="elementToProof">
<span style="font-family: Arial; font-size: 11pt; color: rgb(0, 0, 0);">(short URL:
</span><span style="font-family: Arial; font-size: 11pt; color: rgb(17, 85, 204);"><u><a href="https://urldefense.com/v3/__https://tiny.cc/cryoem_map__;!!Mih3wA!GkK9ZBKg0A4XIR16X_r-0RoDsT6pezrkllFEChtW4XfGvOV4lc0qFETjfz2UbOH0AMhwNrF8v_KCtSS-ZA$" id="OWA419cbddd-811f-f24e-9135-8670d9b8cad8" class="OWAAutoLink" style="color: rgb(17, 85, 204); margin-top: 0px; margin-bottom: 0px;" data-auth="NotApplicable">https://tiny.cc/cryoem_map</a></u></span><span style="font-size: 12pt; color: rgb(0, 0, 0);">)</span></p>
</div>
<div style="direction: ltr; background-color: rgb(255, 255, 255); font-size: 12pt; color: rgb(0, 0, 0);">
<br>
</div>
<div style="direction: ltr; background-color: rgb(255, 255, 255); font-size: 12pt; color: rgb(0, 0, 0);">
Updates include:</div>
<div style="background-color: rgb(255, 255, 255);">
<ul style="direction: ltr;">
<li style="font-size: 12pt; color: rgb(0, 0, 0); direction: ltr;">All Krioses, Glacioses, and Arcticas have been identified to within ~5% error,</li><li style="font-size: 12pt; color: rgb(0, 0, 0); direction: ltr;">A section called 'Cryo-EM tools & other scopes' has been added to catalogue other EMs like screening scopes and general equipment like plunge freezers and sputter coaters,<br>
</li><li style="font-size: 12pt; color: rgb(0, 0, 0); direction: ltr;">Tundras have been added,</li><li style="font-size: 12pt; color: rgb(0, 0, 0); direction: ltr;">200 more cryo-EM labs have been added.</li></ul>
<div style="direction: ltr; font-size: 12pt; color: rgb(0, 0, 0);">I can use your help! I have the following requests:</div>
<ul style="direction: ltr;">
<li style="font-size: 12pt; color: rgb(0, 0, 0); direction: ltr;">For some Krioses, Glacioses, and Arcticas, I only know the city they are in instead of their exact locations. If you know the exact locations for any of these, please email me.</li><li style="font-size: 12pt; color: rgb(0, 0, 0); direction: ltr;">If you work at JEOL and have a list of sub-4 angstrom instruments (CryoARMs, 3200s, etc) to anonymously share with me, please email me.</li><li style="font-size: 12pt; color: rgb(0, 0, 0); direction: ltr;">If you have a microscope on order that is not listed, especially Tundras, please email me.</li><li style="font-size: 12pt; color: rgb(0, 0, 0); direction: ltr;">Feel free to email me a list of general cryo-EM equipment at your institute if it's not on the map already.</li><li style="font-size: 12pt; color: rgb(0, 0, 0); direction: ltr;">Any missing instruments or labs, and general feedback of course!<br>
</li></ul>
<div style="direction: ltr; font-size: 12pt; color: rgb(0, 0, 0);">With over 100,000 views, I think this map has been quite a successful project and will hopefully continue to be useful. Let's keep doing fun science in this awesome field! And let's not forget
to always support each other - there are many more cryo-EM projects than there are people to do them.</div>
<div style="direction: ltr; font-size: 12pt; color: rgb(0, 0, 0);"><br>
</div>
<div style="direction: ltr; font-size: 12pt; color: rgb(0, 0, 0);">Best wishes,</div>
<div style="direction: ltr; font-size: 12pt; color: rgb(0, 0, 0);">Alex Noble, SEMC</div>
</div>
</div>
<div style="background-color: rgb(255, 255, 255);">
<div style="direction: ltr; font-family: Calibri, Arial, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
<br>
</div>
</div>
<div style="direction: ltr; background-color: rgb(255, 255, 255); font-family: Calibri, Arial, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
<br>
</div>
<div id="x_appendonsend" style="color: inherit;"></div>
<div style="direction: ltr; font-family: Calibri, Arial, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
<br>
</div>
<hr style="direction: ltr; display: inline-block; width: 98%;">
<div id="x_divRplyFwdMsg" dir="ltr" style="color: inherit;"><span style="font-family: Calibri, sans-serif; font-size: 11pt; color: rgb(0, 0, 0);"><b>From:</b> Alex Noble<br>
<b>Sent:</b> Tuesday, November 16, 2021 9:02 AM<br>
<b>To:</b> 3dem@ncmir.ucsd.edu <3dem@ncmir.ucsd.edu><br>
<b>Subject:</b> Map of Cryo-EM Worldwide</span>
<div> </div>
</div>
<p style="direction: ltr; line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;">
<span style="font-family: Arial; font-size: 11pt; color: rgb(0, 0, 0);">Dear cool people,</span></p>
<div style="direction: ltr; font-family: Calibri, Arial, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
<br>
</div>
<p style="direction: ltr; line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;">
<span style="font-family: Arial; font-size: 11pt; color: rgb(0, 0, 0);">I would like to share with you an open-source map of cryo-EM instruments and labs worldwide:</span></p>
<div style="direction: ltr; font-family: Calibri, Arial, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
<br>
</div>
<p style="direction: ltr; line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;">
<span style="font-family: Arial; font-size: 11pt; color: rgb(17, 85, 204);"><u><a href="https://urldefense.com/v3/__https://www.google.com/maps/d/viewer?mid=1eQ1r8BiDYfaK7D1S9EeFJEgkLggMyoaT&usp=sharing__;!!Mih3wA!GkK9ZBKg0A4XIR16X_r-0RoDsT6pezrkllFEChtW4XfGvOV4lc0qFETjfz2UbOH0AMhwNrF8v_LmGjCAOw$" id="OWAb48b534d-2df1-9b05-a5df-b3a70eae7e4b" class="OWAAutoLink" style="color: rgb(17, 85, 204); margin-top: 0px; margin-bottom: 0px;" data-auth="NotApplicable">https://www.google.com/maps/d/viewer?mid=1eQ1r8BiDYfaK7D1S9EeFJEgkLggMyoaT&usp=sharing</a></u></span></p>
<div style="direction: ltr; font-family: Calibri, Arial, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
<br>
</div>
<p style="direction: ltr; line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;">
<span style="font-family: Arial; font-size: 11pt; color: rgb(0, 0, 0);">short URL:
</span><span style="font-family: Arial; font-size: 11pt; color: rgb(17, 85, 204);"><u><a href="https://urldefense.com/v3/__https://tiny.cc/cryoem_map__;!!Mih3wA!GkK9ZBKg0A4XIR16X_r-0RoDsT6pezrkllFEChtW4XfGvOV4lc0qFETjfz2UbOH0AMhwNrF8v_KCtSS-ZA$" id="OWA3c408a2d-1afe-cdbe-4feb-f22a410b66a3" class="OWAAutoLink" style="color: rgb(17, 85, 204); margin-top: 0px; margin-bottom: 0px;" data-auth="NotApplicable">https://tiny.cc/cryoem_map</a></u></span></p>
<div style="direction: ltr; font-family: Calibri, Arial, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
<br>
</div>
<p style="direction: ltr; line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;">
<span style="font-family: Arial; font-size: 11pt; color: rgb(0, 0, 0);">A few years ago, Wen Jiang (Purdue) started a cryo-EM google map of Krioses in the USA. With the help of the cryo-EM community on Twitter, Lucas Farnung (Harvard) expanded it to Krioses
worldwide, then I expanded it to CryoARMs, Arcticas, Glacioses, Polaras/TF30s, cryo-FIB/SEMs, and 650 cryo-EM labs.</span></p>
<div style="direction: ltr; font-family: Calibri, Arial, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
<br>
</div>
<p style="direction: ltr; line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;">
<span style="font-family: Arial; font-size: 11pt; color: rgb(0, 0, 0);">The idea is to geographically catalogue all cryo-EM instruments that are capable of routinely producing near-atomic resolution specimens or data, and to geographically catalogue all labs
that perform research in the field of biological cryo-EM. Hopefully this resource allows all cryo-EM scientists to know what instruments and labs exist in their geographical locations of interest so that they can plan their experiments more efficiently and
go where they are treated best.</span></p>
<div style="direction: ltr; font-family: Calibri, Arial, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
<br>
</div>
<p style="direction: ltr; line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;">
<span style="font-family: Arial; font-size: 11pt; color: rgb(0, 0, 0);">I am sure that there are missing instruments, missing labs, and errors in the map. Please contact me by email or Twitter to add/fix anything. My apologies if I have missed your lab! Note:
There is a search function in the map so you can quickly locate labs and equipment.</span></p>
<div style="direction: ltr; font-family: Calibri, Arial, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
<br>
</div>
<p style="direction: ltr; line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;">
<span style="font-family: Arial; font-size: 11pt; color: rgb(0, 0, 0);">Best wishes,</span></p>
<div style="direction: ltr; font-family: Arial; font-size: 11pt;"><span style="color: rgb(0, 0, 0);">Alex Noble (tw:
</span><span style="color: rgb(17, 85, 204);"><u><a href="https://urldefense.com/v3/__https://twitter.com/alexjamesnoble__;!!Mih3wA!GkK9ZBKg0A4XIR16X_r-0RoDsT6pezrkllFEChtW4XfGvOV4lc0qFETjfz2UbOH0AMhwNrF8v_L70Mj7tQ$" id="OWAdee95b75-db90-7717-6c0b-51417c633037" class="OWAAutoLink" style="color: rgb(17, 85, 204);" data-auth="NotApplicable">@alexjamesnoble</a></u></span><span style="color: rgb(0, 0, 0);">),
SEMC</span></div>
</body>
</html>