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<span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">Dear all,<br>
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<span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt"><br>
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<span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">Our team at the IGBMC, near Strasbourg, France, offers a PostDoc position starting in early 2025 for initially 2.5 years.
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<span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">The project will focus on</span><span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">
</span><span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">the in situ (ultra-) structural description of large-scale intracellular transport machinery previously uncharacterized by cryo-ET.
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<span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">This machinery contains different types of cytoskeleton and membranous compartments, providing ample opportunity for ultrastructural analysis, structure determination,
and the development of new processing pipelines for both of these approaches.</span></p>
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<span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt"><br>
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<span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">We are looking for candidates fitting to the following profile: </span></p>
<p style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">
<span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">-Ph.D. degree in structural biology or related field</span></p>
<p style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">
<span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">-Experience in cryo-ET and STA workflows from specimen preparation (optimally including FIB/SEM and cryo-light microscopes) to data processing. Alternatively, comparable
experience for SPA cryo-EM </span></p>
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<span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">-Capability to adapt existing processing pipelines by coding custom scripts</span></p>
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<span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">-Curiosity to engage with a new model system<br>
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<span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">-Proficiency in English</span></p>
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<span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">The successful candidate will have access to the Integrated Structural Biology platform at IGBMC (2 Titan Krios, 1 Glacios,</span><span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">
1 </span><span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">cryo-FIB/SEM, and a cryo-light microscope), allowing them to perform all experiments on-site.</span></p>
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<span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">Details on the position and application procedure can be found here in the 'Projects' section:</span></p>
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<a target="_blank" href="https://urldefense.com/v3/__https:/www.igbmc.fr/en/recherche/teams/cellular-architecture__;!!Mih3wA!BZZMkiRGuPowO3UkQ5wMoC-PsO-O9BT45_91-ztuUEJEl9zN74_TC-AyHlxBfgWaA0Nf5hunPp6rmMMk-Q2Ytw$" class="editor-rtfLink" style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt; color:#4a6ee0"><span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt; color:#4a6ee0"></a><a href="https://urldefense.com/v3/__https://www.igbmc.fr/en/recherche/teams/cellular-architecture__;!!Mih3wA!EAyp8IN4WwnJG8k8ijUqatqFOomMhlAnm8ykMt_R4tFfxpYdCTdJKcJSCQXN0h2AFkvhA0Nfq9L92hpdnlfyHQ$" class="OWAAutoLink">https://www.igbmc.fr/en/recherche/teams/cellular-architecture</a><br>
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<a target="_blank" href="https://urldefense.com/v3/__https:/www.igbmc.fr/en/recherche/teams/cellular-architecture__;!!Mih3wA!BZZMkiRGuPowO3UkQ5wMoC-PsO-O9BT45_91-ztuUEJEl9zN74_TC-AyHlxBfgWaA0Nf5hunPp6rmMMk-Q2Ytw$" class="editor-rtfLink" style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt; color:#4a6ee0"><span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt; color:#4a6ee0"><br>
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<span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">For more information on the project, please feel free to contact
</span><span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">me</span><span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt"> directly.</span></p>
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<span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt"><br>
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<span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">Best,</span></p>
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<span style="color:rgb(14,16,26); background:transparent; margin-top:0pt; margin-bottom:0pt">Florian</span></p>
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<p>________________________________________________<br>
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<p>Florian Fäßler</p>
<p>Inserm Junior Professor Chair<br>
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<p>Department of Integrated Structural Biology</p>
<p><span>Institute of Genetics and of Molecular and Cellular Biology</span> (IGBMC)</p>
<p>1, rue Laurent Fries</p>
<p>BP 10142</p>
<p>67404 Illkirch Cedex</p>
<p>France<br>
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<p>Email: florian.faessler@igbmc.fr</p>
<p><span>________________________________________________</span><br>
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