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<p class="MsoNormal"><span style="mso-ligatures:none;mso-fareast-language:EN-GB">Dear 3DEM list,<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-ligatures:none;mso-fareast-language:EN-GB"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="mso-ligatures:none;mso-fareast-language:EN-GB">A reminder of our open position at DCI-Geneva:
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-ligatures:none;mso-fareast-language:EN-GB"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="mso-ligatures:none;mso-fareast-language:EN-GB">The Dubochet Centre for Imaging in Geneva (DCI-Geneva) are recruiting a cryoEM specialist to join our team.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-ligatures:none;mso-fareast-language:EN-GB"> <o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-ligatures:none;mso-fareast-language:EN-GB"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><span style="mso-ligatures:none;mso-fareast-language:EN-GB">The Role:</span></b><span style="mso-ligatures:none;mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-ligatures:none;mso-fareast-language:EN-GB">The DCI-Geneva cryoEM platform (<a href="https://urldefense.com/v3/__https://cryoem.unige.ch/__;!!Mih3wA!HtSmtV1RIY5rcJaE80-Yl6-N1EFKN_J-ow7kpwvov4k6hTCAeJyIRuy_Ro_hRhmTSANAxY9V6f3UUU28GwXTTf7T7g$"><span style="color:#0563C1">https://cryoem.unige.ch/</span></a>) at the University of Geneva is seeking a passionate
microscopist with expertise in cryoEM analysis and microscope operation. The successful candidate will be part of a team supporting daily operations at DCI-Geneva. This will involve advising and assisting users in the full ‘sample-to-structure’ pipeline, including
sample preparation for negative stain and cryo experiments, screening and data collection on TFS microscopes and data processing to high resolution. The candidate will also assist with maintaining sample preparation facilities and microscopes, including managing
stocks of reagents, and troubleshooting common instrument faults.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-ligatures:none;mso-fareast-language:EN-GB"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><span style="mso-ligatures:none;mso-fareast-language:EN-GB">Candidate profile:</span></b><span style="mso-ligatures:none;mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-ligatures:none;mso-fareast-language:EN-GB">Applicants should hold a PhD or have suitable equivalent experience in electron microscopy of biological samples. The ideal candidate will have experience in optimising conditions
for the preparation of EM grids with biological specimens. Of significant benefit would be experience in troubleshooting the preparation of tricky samples. They should be confident in operating an electron microscope (120 keV – 300 keV TFS instruments) to
screen and collect cryoEM data. Experience in SPA processing is essential, particularly in cases of difficult to solve structures. Furthermore, experience in setting up and maintaining Linux GPU workstations for cryoEM data processing would be highly valued.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-ligatures:none;mso-fareast-language:EN-GB"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><span style="mso-ligatures:none;mso-fareast-language:EN-GB">The environment:</span></b><span style="mso-ligatures:none;mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-ligatures:none;mso-fareast-language:EN-GB">The DCI is a joint initiative of the University of Geneva (UNIGE), the University of Lausanne (UNIL), the École Polytechnique Fédérale de Lausanne (EPFL) and the University of
Bern (UNIBE).<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-ligatures:none;mso-fareast-language:EN-GB">DCI-Geneva boasts a Talos Arctica 200keV TEM complete with Falcon 4i detector and Selectris X imaging filter. Other instruments at the facility include Talos L120C TEM, Tecnai
Sphera G2 TEM equipped for microED, and Leica Thunder cryo-fluorescence microscopes, alongside an extensive range of preparation instruments. There is additionally regular access to Titan Krios microscopes at other DCI sites.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-ligatures:none;mso-fareast-language:EN-GB"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="mso-ligatures:none;mso-fareast-language:EN-GB">Situated between the Alps and the Jura mountains, on the shores of beautiful Lac Léman, Geneva is consistently regarded as one of the world's most liveable cities.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-ligatures:none;mso-fareast-language:EN-GB"> <o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-ligatures:none;mso-fareast-language:EN-GB">This position is available for a period of 2 years and the posting will remain open until filled.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-ligatures:none;mso-fareast-language:EN-GB">To apply, please send your CV along with contact details of at least 2 referees and a brief letter of motivation to <a href="mailto:Andrew.howe@unige.ch"><span style="color:#0563C1">Andrew.howe@unige.ch</span></a>.
Please get in touch for further details or any questions regarding the role.<o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
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