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<p class="MsoNormal"><span style="font-size:14.0pt">This Commentary I wrote has now appeared online at Protein Science. Many people in the cryo-EM community may be unaware that there is actually an “alternate” community of people interested in doing room temperature
EM of biological samples in the liquid phase. My attached Commentary is a rebuttal of the Jonaid et al. paper that has now been positively cited in a number of other papers and reviews. The senior author of the Jonaid et al. paper was the Chair of the Liquid
Phase EM GRC in 2022 and an invited speaker at their 2024 meeting. <o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt">Regards,<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt">Ed<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt"><o:p> </o:p></span></p>
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<p class="MsoNormal"><span style="font-size:10.5pt;font-family:"Calibri",sans-serif;color:black;mso-ligatures:none">Edward Egelman<o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:10.5pt;font-family:"Calibri",sans-serif;color:black;mso-ligatures:none">Harrison Distinguished Professor,<o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:10.5pt;font-family:"Calibri",sans-serif;color:black;mso-ligatures:none">Department of Biochemistry and Molecular Genetics<o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:10.5pt;font-family:"Calibri",sans-serif;color:black;mso-ligatures:none">Professor of Molecular Physiology and Biological Physics</span><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;mso-ligatures:none"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.5pt;font-family:"Calibri",sans-serif;color:black;mso-ligatures:none">University of Virginia</span><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;mso-ligatures:none"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:10.5pt;font-family:"Calibri",sans-serif;color:black;mso-ligatures:none">phone: 434-924-8210<o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:10.5pt;font-family:"Calibri",sans-serif;color:black;mso-ligatures:none">fax: 434-924-5069<o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:10.5pt;font-family:"Calibri",sans-serif;color:black;mso-ligatures:none"><a href="mailto:egelman@virginia.edu"><span style="color:blue">egelman@virginia.edu</span></a><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.5pt;font-family:"Calibri",sans-serif;color:black;mso-ligatures:none"><a href="https://urldefense.com/v3/__https://egelmanlab.org/__;!!Mih3wA!Hxk_kkykWbjrOOGsBkwn7aIXXDe9QUSDUGXBPziamsSVTFeBNTW0G6RRl1evO6d2hwvX46Z6viPjy7kTGgLGx9w$"><span style="color:blue">https://egelmanlab.org/</span></a><o:p></o:p></span></p>
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<p class="MsoNormal"><o:p> </o:p></p>
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