<html xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40">
<head>
<meta http-equiv="Content-Type" content="text/html; charset=Windows-1252">
<meta name="Generator" content="Microsoft Word 15 (filtered medium)">
<style><!--
/* Font Definitions */
@font-face
{font-family:"Cambria Math";
panose-1:2 4 5 3 5 4 6 3 2 4;}
@font-face
{font-family:Calibri;
panose-1:2 15 5 2 2 2 4 3 2 4;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{margin:0in;
font-size:12.0pt;
font-family:"Calibri",sans-serif;}
a:link, span.MsoHyperlink
{mso-style-priority:99;
color:#0563C1;
text-decoration:underline;}
span.EmailStyle20
{mso-style-type:personal-reply;
font-family:"Calibri",sans-serif;
color:windowtext;}
.MsoChpDefault
{mso-style-type:export-only;
font-size:12.0pt;
font-family:"Calibri",sans-serif;}
@page WordSection1
{size:8.5in 11.0in;
margin:1.0in 1.0in 1.0in 1.0in;}
div.WordSection1
{page:WordSection1;}
--></style>
</head>
<body lang="EN-US" link="#0563C1" vlink="#954F72" style="word-wrap:break-word">
<div class="WordSection1">
<p class="MsoNormal"><span style="font-size:11.0pt">Do you know what grade level this position is?<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt">56, 57, 58?<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Thanks<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Nicki<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<div style="border:none;border-top:solid #B5C4DF 1.0pt;padding:3.0pt 0in 0in 0in">
<p class="MsoNormal" style="margin-bottom:12.0pt"><b><span style="color:black">From:
</span></b><span style="color:black">3dem <3dem-bounces@ncmir.ucsd.edu> on behalf of Walsh, Richard <Richard_Walsh@hms.harvard.edu><br>
<b>Date: </b>Thursday, April 18, 2024 at 12:03 PM<br>
<b>To: </b>3dem@ncmir.ucsd.edu <3dem@ncmir.ucsd.edu><br>
<b>Subject: </b>[3dem] Cryo-EM specialist position at Harvard Medical School<o:p></o:p></span></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black">A cryo-EM specialist position at Harvard Medical School is currently available. Interested candidates should submit a cover letter, CV, and contact information for two
references, to the managing director, Dr. Richard Walsh, via <a href="mailto:Richard_walsh@hms.harvard.edu">
Richard_walsh@hms.harvard.edu</a>.In the Subject line of your email, please write: Cryo-EM Specialist.</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black">Cryo-EM Specialist position</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black">Harvard Medical School houses two core facilities providing access to negative stain and cryo-EM instrumentation; we are looking for a highly motivated scientist to join
our team. The Harvard Cryo-EM Center for Structural Biology, formed as a consortium between HMS, Boston Children's Hospital, Dana-Farber Cancer Institute, and Massachusetts General Hospital, serves the consortium members and a variety of external academic
and commercial users. The Molecular Electron Microscopy Suite is a training resource for Quad-based researchers at Harvard Medical School(<a href="https://urldefense.com/v3/__https:/cryoem.hms.harvard.edu/__;!!Mih3wA!DKFiMMi6bbjeDELvoIO5rY-JeDPrDiHLFH4JXRpM6U9eh2MZw_g2XL7teg9bj4cFaLG0dSgmbuxm8amI8ihc_uhVX_RmwkDe0g$">https://cryoem.hms.harvard.edu/</a></span><span style="font-size:10.0pt;font-family:"Courier New"">)<span style="color:black">.</span></span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black">The successful candidate will provide support and training for researchers seeking to learn cryo-EM and negative-stain EM in these two facilities, serving as an interface
between the instrumentation and a vibrant scientific community. The candidate will work closely with a team of scientists to support many structural biology projects in many research areas and will take on facility management responsibilities.</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black">Key Roles:</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> * Serve as the technical interface between users and the Talos Arctica and Titan Krios microscopes by loading samples and checking microscope alignments.</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> * Train users to operate TEM microscopes, specifically the Tecnai T12, Talos Arctica, and Titan Krios; including sample preparation (negative stain and cryo-plunging),
grid loading, sample screening, and data collection.</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> * Advise researchers on experimental strategy and, when appropriate, collaborate with them to assist in data acquisition, analysis, and structure determination.</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> * Interact closely with the core facilities’ team to manage microscope and equipment maintenance, coordinate user scheduling and training, and interface with SBGrid
to assist with the computational needs of both facilities.</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black">This position will have a high degree of independence, opportunities to present at regional and national scientific symposia and workshops, and opportunities to develop
collaborative relationships with Harvard community investigators.</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black">Requirements:</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> * Ph.D. in a field related to structural biology such as cell biology or biochemistry. Experience in structural biology at the postdoctoral level is desired.</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> * Experience with negative stain EM and cryo-EM.
</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> * Experience with TEMs with Autoloader systems i.e Galcios, Talos Arctica or Titan Krios</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> * Experience with Cryo-EM Data Processing</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> * Experience with Biochemical optimization for cryo-EM projects</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> * Experience with Molecular model building into Cryo-EM Maps</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> * Must be detail-oriented and able to manage multiple projects simultaneously.</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> * Good communication and interpersonal skills.</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Courier New";color:black">Harvard is an Affirmative Action/Equal Opportunity Employer. Applications from women and minority candidates are strongly encouraged. All qualified applicants will receive
consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions or any other characteristic protected by
law.</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:8.0pt;font-family:"Arial",sans-serif;color:#666666">Richard M. Walsh , Ph.D.</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:8.0pt;font-family:"Arial",sans-serif;color:black"><br>
</span><span style="font-size:8.0pt;font-family:"Arial",sans-serif;color:#666666">The Harvard Cryo-EM Center for Structural Biology </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:8.0pt;font-family:"Arial",sans-serif;color:#666666">Harvard Medical School, 250 Longwood Avenue, SGM 102A, Boston, MA 02115</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:8.0pt;font-family:"Arial",sans-serif;color:black"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:8.0pt;font-family:"Arial",sans-serif;color:#666666">Phone: (617) 432-9042<br>
Email: </span><span style="font-size:8.0pt;font-family:"Arial",sans-serif;color:black"><a href="https://urldefense.com/v3/__https:/mail.swmed.edu/OWA/redir.aspx?C=zX-j7PPuaa4ByRzJw5IbwSyh41uyB3ZobdzY9VXwRQ95WICTIhTWCA..&URL=mailto*3aSarah_Sterling*40hms.harvard.edu__;JSU!!Mih3wA!DKFiMMi6bbjeDELvoIO5rY-JeDPrDiHLFH4JXRpM6U9eh2MZw_g2XL7teg9bj4cFaLG0dSgmbuxm8amI8ihc_uhVX_RkV9MYkQ$" target="_blank"><span style="color:#1155CC">Richard_Walsh@hms.harvard.edu</span></a></span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:8.0pt;font-family:"Arial",sans-serif;color:#666666">Web: </span><span style="font-size:8.0pt;font-family:"Arial",sans-serif;color:black"><a href="https://urldefense.com/v3/__http:/cryoem.hms.harvard.edu/__;!!Mih3wA!DKFiMMi6bbjeDELvoIO5rY-JeDPrDiHLFH4JXRpM6U9eh2MZw_g2XL7teg9bj4cFaLG0dSgmbuxm8amI8ihc_uhVX_RNcDizvQ$" target="_blank"><span style="color:#1155CC">cryoem.hms.harvard.edu</span></a></span><o:p></o:p></p>
<p class="MsoNormal"> <o:p></o:p></p>
</div>
</div>
</body>
</html>