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<p class="MsoNormal"><span style="font-size:12.0pt;color:#212121">Dear all,</span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-size:12.0pt;color:#212121"> </span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-size:12.0pt;color:#212121">We have an open position for a postdoc to work on establishing time-resolved cryo-EM to study the mechanism of DNA helicases with therapeutic potential. The position is a part of the AZ-Crick Alliance and will be
jointly supervised between the Enchev lab at the Francis Crick Institute and the Structural Biology team at AstraZeneca UK.</span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-size:12.0pt;color:#212121"> </span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-size:12.0pt;color:#141414">AstraZeneca and the Francis Crick Institute have established a productive research collaboration, supporting discovery biology research and early translational projects since December 2016. This has brought together
the combined knowledge and capability of Crick and AZ scientists to work on areas of technology development, mechanistic understanding and novel target validation.</span><span style="color:#212121"><o:p></o:p></span></p>
<p style="margin-bottom:12.0pt;background:white;caret-color: rgb(33, 33, 33);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-stroke-width: 0px;word-spacing:0px">
<span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#141414">For a full job description and details on how to apply, please follow this link:</span><span class="apple-converted-space"><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#141414"> </span></span><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#141414"><a href="https://urldefense.com/v3/__https://www.crick.ac.uk/careers-study/vacancies/2024-02-07-senior-laboratory-research-scientist-structural-biochemist__;!!Mih3wA!DtB90KtzLTLt8OcQZtvTBTjEv2965ZvC783jQsBZ5NROlbYiC3BRZr-RRTzZGtGKzyrObpWrQZ9VnHHCf4J0aIsPdKBH$" title="https://protect-de.mimecast.com/s/PzxsCz6rEACxXRXPzH4d8BU?domain=crick.ac.uk"><span style="color:#0078D7">https://www.crick.ac.uk/careers-study/vacancies/2024-02-07-senior-laboratory-research-scientist-structural-biochemist</span></a></span><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#212121"><o:p></o:p></span></p>
<p style="margin-bottom:12.0pt;background:white;caret-color: rgb(33, 33, 33);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-stroke-width: 0px;word-spacing:0px">
<span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#141414">Application deadline: 6<sup>th</sup></span><span class="apple-converted-space"><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#141414"> </span></span><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#141414">March</span><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#212121"><o:p></o:p></span></p>
<p class="MsoNormal" style="caret-color: rgb(33, 33, 33);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-stroke-width: 0px;word-spacing:0px">
<span style="font-size:12.0pt;color:#212121">Please feel free to contact either Radoslav Enchev (<a href="mailto:Radoslav.enchev@crick.ac.uk" title="mailto:Radoslav.enchev@crick.ac.uk"><span style="color:#0078D7">Radoslav.enchev@crick.ac.uk</span></a>), Taiana
Maia de Oliveira (<a href="mailto:taiana.maiadeoliveira@astrazeneca.com" title="mailto:taiana.maiadeoliveira@astrazeneca.com"><span style="color:#0078D7">taiana.maiadeoliveira@astrazeneca.com</span></a>) or myself (<a href="mailto:oliver.acton@astrazeneca.com" title="mailto:oliver.acton@astrazeneca.com"><span style="color:#0078D7">oliver.acton@astrazeneca.com</span></a>)
if you have any further questions about the role.</span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-size:12.0pt;color:#212121"> </span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-size:12.0pt;color:#212121">Best wishes,</span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-size:12.0pt;color:#212121"> </span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-size:12.0pt;color:#212121">Oliver</span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="font-size:12.0pt;color:#212121"> </span><span style="color:#212121"><o:p></o:p></span></p>
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<b><span lang="EN-US" style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#760040">Oliver Acton, Ph.D.</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<span lang="EN-US" style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#18376A">Associate Principal Scientist – Cryo Electron Microscopy</span><span style="color:#212121"><o:p></o:p></span></p>
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<span lang="EN-US" style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#18376A">Mechanistic and Structural Biology</span><span style="color:#212121"><o:p></o:p></span></p>
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<span lang="EN-US" style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#18376A">_____________________________________</span><span style="color:#212121"><o:p></o:p></span></p>
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<span lang="EN-US" style="font-size:9.0pt;font-family:"Times New Roman",serif;color:#212121"> </span><span style="color:#212121"><o:p></o:p></span></p>
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<b><span lang="EN-US" style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#760040">AstraZeneca</span></b><span lang="EN-US" style="font-size:9.0pt;color:#212121"> </span><b><span lang="EN-US" style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#760040">R&D,
Discovery Sciences</span></b><span style="color:#212121"><o:p></o:p></span></p>
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<span lang="EN-US" style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#18376A">The Discovery Centre</span><span style="color:#212121"><o:p></o:p></span></p>
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<span lang="EN-US" style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#18376A">1 Francis Crick Avenue</span><span style="color:#212121"><o:p></o:p></span></p>
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<span lang="EN-US" style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#18376A">Cambridge, CB2 0AA, UK</span><span style="color:#212121"><o:p></o:p></span></p>
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<span lang="EN-US" style="font-size:9.0pt;font-family:"Arial",sans-serif;color:#18376A"><a href="mailto:oliver.acton@astrazeneca.com" title="mailto:oliver.acton@astrazeneca.com"><span style="color:#0078D7">oliver.acton@astrazeneca.com</span></a></span><span style="color:#212121"><o:p></o:p></span></p>
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<span style="color:#212121"> <o:p></o:p></span></p>
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