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<p class="MsoNormal" style="margin-left:212.4pt;text-indent:35.4pt"><a name="OLE_LINK1"></a><a name="OLE_LINK2"></a><a name="OLE_LINK3"></a><a name="OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-GB" style="font-family:"Segoe UI",sans-serif;color:black;background:white">Post-Doc/Research
Engineer in "ADVANCED OPTICAL AND CRYO-ELECTRON TOMOGRAPHY IMAGING OF THE BACTERIAL CELL ENVELOPE"
</span></span></span></span></a><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-GB" style="font-family:"Segoe UI",sans-serif;background:white"><o:p></o:p></span></span></span></span></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"></span></span></span></span><a href="https://urldefense.com/v3/__https://www.linkedin.com/company/institut-pasteur/__;!!Mih3wA!EbsICSRLyrtcXIGAuLMMmAT19-Q7zCsXCMGMx_pFR8UryVDST6laqt9VIZLGEJi8OIOAIAoiP2Kh0xIYjCNBd1togZOpzVbK$" target="_self"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span style="font-family:"Segoe UI",sans-serif;background:white">Institut
Pasteur</span></span></span></span></span><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"></span></span></span></span></a><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span style="font-family:"Segoe UI",sans-serif;color:black;background:white">,
Paris, France</span></span></span></span></span><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span style="font-family:"Segoe UI",sans-serif;background:white"><o:p></o:p></span></span></span></span></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"></span></span></span></span><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span style="font-family:"Segoe UI",sans-serif;background:white"><o:p> </o:p></span></span></span></span></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-GB"><img border="0" width="392" height="97" style="width:4.0833in;height:1.0138in" id="Groupe_x0020_2" src="cid:image001.png@01DA52A2.45B06A60"></span></span></span></span></span><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span style="font-family:"Segoe UI",sans-serif;color:black;background:white">@
<span class="white-space-pre"> </span></span></span></span></span></span><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span style="font-family:"Segoe UI",sans-serif;background:white"><o:p></o:p></span></span></span></span></span></p>
<p class="MsoNormal"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span class="white-space-pre"><span style="font-size:10.5pt;font-family:"Segoe UI",sans-serif;color:black;background:white"> </span></span><o:p></o:p></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><b><span style="font-family:"Arial",sans-serif">General
Information</span></b></span></span></span></span><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span style="font-family:"Arial",sans-serif">
<o:p></o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif">A
24-month postdoc position is available at Institut Pasteur, Paris, France. We are looking for a highly motivated candidate to
<b>study the bacterial cell envelope by cutting-edge 3D optical and cryo-electron tomography imaging</b>.<o:p></o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif"><o:p> </o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif">The
candidate will be working at the interface between the team of </span></span></span></span></span><a href="https://urldefense.com/v3/__https://research.pasteur.fr/en/member/simonetta-gribaldo/__;!!Mih3wA!EbsICSRLyrtcXIGAuLMMmAT19-Q7zCsXCMGMx_pFR8UryVDST6laqt9VIZLGEJi8OIOAIAoiP2Kh0xIYjCNBd1togewgM-j5$"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-GB" style="font-family:"Arial",sans-serif">Simonetta
Gribaldo</span></span></span></span></span><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"></span></span></span></span></a><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-GB" style="font-family:"Arial",sans-serif">,
head of the Evolutionary Biology of the Microbial Cell</span></span></span></span></span><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif">
at the Department of Microbiology, and the team of </span></span></span></span></span><a href="https://urldefense.com/v3/__https://research.pasteur.fr/en/member/anna-sartori-rupp/__;!!Mih3wA!EbsICSRLyrtcXIGAuLMMmAT19-Q7zCsXCMGMx_pFR8UryVDST6laqt9VIZLGEJi8OIOAIAoiP2Kh0xIYjCNBd1togVl5K3qZ$"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-GB" style="font-family:"Arial",sans-serif">Anna
Sartori-Rupp</span></span></span></span></span><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"></span></span></span></span></a><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif">
at the </span></span></span></span></span><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-GB" style="font-family:"Arial",sans-serif">NanoImaging
core facility</span></span></span></span></span><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-GB" style="font-family:"Arial",sans-serif">
</span></span></span></span></span><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif">of Institut Pasteur.
<o:p></o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif"><o:p> </o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif">The
Gribaldo’s lab studies the bacterial cell envelope, and particularly the transition between Gram-negatives (or diderms) and Gram-positives (or monoderms). The lab has developed a new experimental model,
<i>Veillonella parvula</i> (diderm Firmicutes), an important anaerobic member of the human microbiome. A large range of protocols and genetic tools are available to manipulate this bacterium and characterize its envelope. Recently, a
<i>V. parvula</i> mutant was obtained where the outer membrane is highly destabilized, opening multiple possibilities to study the diderm-to-monoderm transition in the lab.
<o:p></o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif"><o:p> </o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif">In
collaboration with A. Sartori-Rupp, the Gribaldo’s lab has established cryo-electron tomography pipelines to provide a unique view of the bacterial cell envelope preserved as close as possible to its native state. The project will focus on visualizing for
the first time the structural organization of the cell envelope in members of several bacterial lineages with nanometer scale resolution. The main aim is to create an atlas of the diversity of bacterial cell envelopes that will provide invaluable information
on the transition between diderm and monoderm bacteria. <o:p></o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif"><o:p> </o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif">This
technological project will be carried out in a stimulating multidisciplinary environment, between the Gribaldo’s research group and the Light and Cryo-Electron Microscopy imaging facilities of Institut Pasteur. The candidate will have full access to cutting-edge
optical and cryo-electron microscopy infrastructure and expertise. The </span></span></span></span></span><a href="https://urldefense.com/v3/__https://research.pasteur.fr/en/team/nanoimaging/__;!!Mih3wA!EbsICSRLyrtcXIGAuLMMmAT19-Q7zCsXCMGMx_pFR8UryVDST6laqt9VIZLGEJi8OIOAIAoiP2Kh0xIYjCNBd1togRLaogiG$"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif;color:windowtext;text-decoration:none">cryo-EM
facility</span></span></span></span></span><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"></span></span></span></span></a><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif"> of
Institut Pasteur features state-of-the-art instrumentation upgraded to the latest standards for single particles and cellular studies. These include: a Titan Krios G3i Cryo-TEM equipped with a cold FEG, a SelectrisX imaging filter and a Falcon4i direct electron
detector and phase plates, two Glacios with Falcon4i direct electron detectors and one with Selectris energy filter and Ceta-D camera for MicroED analysis, an Aquilos2 cryo-FIB/SEM system with cryo-lift-out and iFLM module, a Leica cryo-light Thunder Imager
EM cryo-CLEM microscope & a cryo-Stellaris confocal system. <o:p></o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif"><o:p> </o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><b><span lang="EN-US" style="font-family:"Arial",sans-serif">Project
Description<o:p></o:p></span></b></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif">The
hired postdoc will focus on the following objectives: <o:p></o:p></span></span></span></span></span></p>
<ol style="margin-top:0cm" start="1" type="1">
<li class="MsoListParagraphCxSpFirst" style="margin-left:2.5pt;mso-add-space:auto;text-align:justify;mso-list:l0 level1 lfo1;text-autospace:none">
<span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-size:11.0pt;font-family:"Arial",sans-serif">Obtain the first high-resolution images
of the cell envelope in members of different bacterial lineages presenting various sizes and shapes by using cryo-electron tomography combined with semi-automated cryo-FIB/SEM lamellae.
<o:p></o:p></span></span></span></span></span></li><li class="MsoListParagraphCxSpMiddle" style="margin-left:2.5pt;mso-add-space:auto;text-align:justify;mso-list:l0 level1 lfo1;text-autospace:none">
<span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-size:11.0pt;font-family:"Arial",sans-serif">Develop fluorescence high-resolution
live imaging for the model bacterium <i>V. parvula</i> in strict anaerobia conditions.<o:p></o:p></span></span></span></span></span></li><li class="MsoListParagraphCxSpLast" style="margin-left:2.5pt;mso-add-space:auto;text-align:justify;mso-list:l0 level1 lfo1;text-autospace:none">
<span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-size:11.0pt;font-family:"Arial",sans-serif">Phenotypically characterize a series
of mutant strains with destabilized envelopes. <o:p></o:p></span></span></span></span></span></li></ol>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif"><o:p> </o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif"><o:p> </o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><b><span lang="EN-US" style="font-family:"Arial",sans-serif">Requested
profile<o:p></o:p></span></b></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif">The
candidate will have a solid background and documented experience in one or several of the following fields: structural biology, electron microscopy, 3D visualization, and/or image processing and cell biology. Previous experience in bacterial cell envelopes
and/or manipulation of anaerobes is welcome although not strictly necessary. We are looking for someone with a strong motivation in addressing technological challenges and open the way to methodology advancement in the relatively young field of procaryotic
cell biology. <o:p></o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif"><o:p> </o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif">The
postdoctoral fellow will enjoy a highly interdisciplinary and collaborative environment within a group of complementary expertise and subjects (experimental/bioinformatics; Bacteria/Archaea) led by
</span></span></span></span></span><a href="https://urldefense.com/v3/__https://research.pasteur.fr/en/member/simonetta-gribaldo/__;!!Mih3wA!EbsICSRLyrtcXIGAuLMMmAT19-Q7zCsXCMGMx_pFR8UryVDST6laqt9VIZLGEJi8OIOAIAoiP2Kh0xIYjCNBd1togewgM-j5$"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif">Simonetta
Gribaldo</span></span></span></span></span><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"></span></span></span></span></a><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif">
and will be co-supervised by </span></span></span></span></span><a href="https://urldefense.com/v3/__https://research.pasteur.fr/en/member/anna-sartori-rupp/__;!!Mih3wA!EbsICSRLyrtcXIGAuLMMmAT19-Q7zCsXCMGMx_pFR8UryVDST6laqt9VIZLGEJi8OIOAIAoiP2Kh0xIYjCNBd1togVl5K3qZ$"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-GB" style="font-family:"Arial",sans-serif">Anna
Sartori-Rupp</span></span></span></span></span><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"></span></span></span></span></a><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif">
() at the NanoImaging core facility (Matthijn Vos - </span></span></span></span></span><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-GB" style="font-family:"Arial",sans-serif">NanoImaging
Core</span></span></span></span></span><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif"> - Research
- Institut Pasteur) of Institut Pasteur. <o:p></o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif"><o:p> </o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif">The
position is immediately available. Benefits include comprehensive healthcare coverage for the fellow and their family, and 8 weeks paid annual leave. The Institut Pasteur is in the center of Paris, it has multiple state of-the-art facilities and constitutes
a vibrant research community with 13 Departments across the Biology/Physics/Biomedical fields.<o:p></o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif"><o:p> </o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><b><span lang="EN-US" style="font-family:"Arial",sans-serif">Application
<o:p></o:p></span></b></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif">Candidates
should send a motivation letter including a brief statement of research experience, technical expertise and interest for the project, a full CV and list of publications and the contact detail of three referees to Simonetta Gribaldo & Anna Sartori-Rupp:<o:p></o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif"><o:p> </o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;line-height:150%;text-autospace:none">
<span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"></span></span></span></span><a href="mailto:simonetta.gribaldo@pasteur.fr"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif">simonetta.gribaldo@pasteur.fr</span></span></span></span></span><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"></span></span></span></span></a><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif"><o:p></o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;line-height:150%;text-autospace:none">
<span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"></span></span></span></span><a href="mailto:anna.sartori-rupp@pasteur.fr"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif">anna.sartori-rupp@pasteur.fr</span></span></span></span></span><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"></span></span></span></span></a><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif"><o:p></o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-family:"Arial",sans-serif"><o:p> </o:p></span></span></span></span></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><u><span lang="EN-US" style="font-family:"Arial",sans-serif">Selected
literature:<o:p></o:p></span></u></span></span></span></span></p>
<ol style="margin-top:0cm" start="1" type="1">
<li class="MsoListParagraphCxSpFirst" style="margin-left:0cm;mso-add-space:auto;text-align:justify;mso-list:l1 level1 lfo2">
<span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-size:11.0pt;font-family:"Arial",sans-serif">Megrian D, Taib N, Witwinowski J,
Beloin C, Gribaldo S (2020) One or two membranes? Diderm Firmicutes challenge the Gram-positive/Gram-negative divide.
<i>Mol Microbiol</i> 03;113(3):659-671. <o:p></o:p></span></span></span></span></span></li><li class="MsoListParagraphCxSpLast" style="margin-left:0cm;mso-add-space:auto;text-align:justify;mso-list:l1 level1 lfo2">
<span style="mso-bookmark:OLE_LINK4"><span style="mso-bookmark:OLE_LINK3"><span style="mso-bookmark:OLE_LINK2"><span style="mso-bookmark:OLE_LINK1"><span lang="EN-US" style="font-size:11.0pt;font-family:"Arial",sans-serif">Witwinowski J, Sartori-Rupp A, Taib
N, Pende N, Tham TN, Poppleton D, Ghigo JM, Beloin C, Gribaldo S (2022) An ancient divide in outer membrane tethering systems in Bacteria suggests a mechanism for the diderm-to-monoderm transition.
<i>Nat Microbiol</i> 7, 411–422. </span></span></span></span></span><span lang="EN-US" style="font-size:11.0pt;font-family:"Arial",sans-serif"><o:p></o:p></span></li></ol>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US" style="font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US" style="font-family:"Arial",sans-serif">Links to the labs webpages:<o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><a href="https://urldefense.com/v3/__https://research.pasteur.fr/fr/member/anna-sartori-rupp/__;!!Mih3wA!EbsICSRLyrtcXIGAuLMMmAT19-Q7zCsXCMGMx_pFR8UryVDST6laqt9VIZLGEJi8OIOAIAoiP2Kh0xIYjCNBd1togaN-VUgS$"><span lang="EN-US" style="font-family:"Arial",sans-serif">https://research.pasteur.fr/fr/member/anna-sartori-rupp/</span></a><span lang="EN-US" style="font-family:"Arial",sans-serif"><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><a href="https://urldefense.com/v3/__https://research.pasteur.fr/en/member/simonetta-gribaldo/__;!!Mih3wA!EbsICSRLyrtcXIGAuLMMmAT19-Q7zCsXCMGMx_pFR8UryVDST6laqt9VIZLGEJi8OIOAIAoiP2Kh0xIYjCNBd1togewgM-j5$"><span lang="EN-US" style="font-family:"Arial",sans-serif">https://research.pasteur.fr/en/member/simonetta-gribaldo/</span></a><span lang="EN-US" style="font-family:"Arial",sans-serif"><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US" style="font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US" style="font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><span lang="EN-GB" style="font-size:7.0pt;font-family:"Arial",sans-serif;color:#002060;mso-ligatures:none;mso-fareast-language:FR">-----------------------------------------------<o:p></o:p></span></b></p>
<p class="MsoNormal" style="margin-bottom:6.0pt"><b><span lang="EN-GB" style="font-size:10.0pt;color:#002060;background:white;mso-ligatures:none;mso-fareast-language:FR">Anna Sartori-Rupp</span></b><span lang="EN-GB" style="font-size:10.0pt;color:#002060;mso-ligatures:none;mso-fareast-language:FR"><o:p></o:p></span></p>
<p class="MsoNormal"><b><span lang="EN-GB" style="font-size:8.0pt;color:#0066CC;background:white;mso-ligatures:none;mso-fareast-language:FR">NanoImaging</span></b><b><span lang="EN-GB" style="font-size:8.0pt;color:#006FC9;background:white;mso-ligatures:none;mso-fareast-language:FR"> Core
F</span></b><b><span lang="EN-GB" style="font-size:8.0pt;color:#006FC9;mso-ligatures:none;mso-fareast-language:FR">acility - NCF</span></b><span lang="EN-GB" style="font-size:8.0pt;mso-ligatures:none;mso-fareast-language:FR"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-GB" style="font-size:8.0pt;color:#006FC9;background:white;mso-ligatures:none;mso-fareast-language:FR">Institut Pasteur | Nocard Building 55
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du Dr Roux | 75015 Paris, France<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:8.0pt;color:#006FC9;background:white;mso-ligatures:none;mso-fareast-language:FR"><a href="tel:+33145688710"><span lang="FR" style="color:#0078D4">+33 (0)1 45 68 87 10</span></a></span><span style="font-size:8.0pt;color:#006FC9;background:white;mso-ligatures:none;mso-fareast-language:FR"><o:p></o:p></span></p>
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<a href="mailto:sartori@pasteur.fr">sartori@pasteur.fr</a><o:p></o:p></span></p>
<p class="MsoNormal"><b><span style="font-size:7.0pt;font-family:"Arial",sans-serif;color:#002060;mso-ligatures:none;mso-fareast-language:FR">-----------------------------------------------------------------------------------<o:p></o:p></span></b></p>
<p class="MsoNormal"><span style="font-size:8.0pt;color:#0078D4;mso-ligatures:none;mso-fareast-language:FR"><a href="https://urldefense.com/v3/__https://research.pasteur.fr/en/member/anna-sartori-rupp/__;!!Mih3wA!EbsICSRLyrtcXIGAuLMMmAT19-Q7zCsXCMGMx_pFR8UryVDST6laqt9VIZLGEJi8OIOAIAoiP2Kh0xIYjCNBd1togVl5K3qZ$"><span style="color:#0078D4">https://research.pasteur.fr/en/member/anna-sartori-rupp/</span></a><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:8.0pt;color:#0078D4;mso-ligatures:none;mso-fareast-language:FR"><a href="https://urldefense.com/v3/__https://clexm.eu/projects/__;!!Mih3wA!EbsICSRLyrtcXIGAuLMMmAT19-Q7zCsXCMGMx_pFR8UryVDST6laqt9VIZLGEJi8OIOAIAoiP2Kh0xIYjCNBd1togZe9PjRf$">https://clexm.eu/projects/</a><o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:4.0pt"><u><span style="font-size:8.0pt;color:#0078D4;mso-ligatures:none;mso-fareast-language:FR"><a href="https://urldefense.com/v3/__https://www.comulis.eu/cig-multemplex__;!!Mih3wA!EbsICSRLyrtcXIGAuLMMmAT19-Q7zCsXCMGMx_pFR8UryVDST6laqt9VIZLGEJi8OIOAIAoiP2Kh0xIYjCNBd1togbUbaf9m$">https://www.comulis.eu/cig-multemplex</a><o:p></o:p></span></u></p>
<p class="MsoNormal" style="margin-bottom:4.0pt"><img border="0" width="132" height="65" style="width:1.375in;height:.6736in" id="Image_x0020_2" src="cid:image002.jpg@01DA52A2.45B06A60" alt="Une image contenant texte, Police, capture d’écran, diagramme
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