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<p style="margin:0in"><span style="font-family:"Arial",sans-serif;color:black">Hi</span><span class="apple-converted-space"><span style="font-family:"Arial",sans-serif;color:black"> </span></span><span class="outlook-search-highlight"><span style="font-family:"Arial",sans-serif;color:black">3DEM</span></span><span class="apple-converted-space"><span style="font-family:"Arial",sans-serif;color:black"> </span></span><span style="font-family:"Arial",sans-serif;color:black">colleagues,</span><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#212121"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#212121"><br style="caret-color: rgb(33, 33, 33);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-stroke-width: 0px;word-spacing:0px">
<br>
</span><o:p></o:p></p>
<p style="margin:0in"><span style="font-family:"Arial",sans-serif;color:black">We’re excited to share the beta release of the</span><span class="apple-converted-space"><span style="font-family:"Arial",sans-serif;color:black"> </span></span><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#212121"><a href="https://urldefense.com/v3/__https://cryoetdataportal.czscience.com/__;!!Mih3wA!CB7Nk5GhJMqhVh3cMLwiHj3lYuJ-GhyBH-iEZ_PmIiThmY2DTxZxOzLWTXOTQ9WGI9GfxkEAKvWPNJJkyVA21A$" title="https://cryoetdataportal.czscience.com/"><span style="font-size:11.0pt;font-family:"Arial",sans-serif;color:#0078D7">CryoET
Data Portal</span></a></span><span style="font-family:"Arial",sans-serif;color:black">. This project, built jointly by the Chan Zuckerberg Imaging Institute and the Chan Zuckerberg Initiative, provides biologists and developers with open access to high-quality,
standardized, annotated cryo-electron tomography data they can use to retrain or develop new annotation models and algorithms. Users can find and visualize cryo-ET datasets in the portal and download them for use in their work. </span><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#212121"><o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p style="margin:0in"><span style="font-family:"Arial",sans-serif;color:black">The portal currently contains over 13,000 tomograms from nearly 300 datasets. We’re also working with</span><span class="apple-converted-space"><span style="font-family:"Arial",sans-serif;color:black"> </span></span><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#212121"><a href="https://urldefense.com/v3/__https://www.ebi.ac.uk/empiar/__;!!Mih3wA!CB7Nk5GhJMqhVh3cMLwiHj3lYuJ-GhyBH-iEZ_PmIiThmY2DTxZxOzLWTXOTQ9WGI9GfxkEAKvWPNJLj4QmjLA$" title="https://www.ebi.ac.uk/empiar/"><span style="font-size:11.0pt;font-family:"Arial",sans-serif;color:#0078D7">EMPIAR</span></a></span><span style="font-family:"Arial",sans-serif;color:black">to
host the data and support annotation in the future. We invite community members like you to contribute to what we hope will become a large database of validated 3D structural information for cells that researchers can use to gain new insights into cellular
and structural biology. If you’re interested in sharing datasets and/or annotations to existing data, please</span><span class="apple-converted-space"><span style="font-family:"Arial",sans-serif;color:black"> </span></span><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#212121"><a href="https://urldefense.com/v3/__https://airtable.com/apppmytRJXoXYTO9w/shr5UxgeQcUTSGyiY?prefill_Event=3dem202312&hide_Event=true__;!!Mih3wA!CB7Nk5GhJMqhVh3cMLwiHj3lYuJ-GhyBH-iEZ_PmIiThmY2DTxZxOzLWTXOTQ9WGI9GfxkEAKvWPNJI6lZvN2Q$" title="https://airtable.com/apppmytRJXoXYTO9w/shr5UxgeQcUTSGyiY?prefill_Event=3dem202312&hide_Event=true"><span style="font-size:11.0pt;font-family:"Arial",sans-serif;color:#0078D7">fill
out this short form</span></a></span><span style="font-family:"Arial",sans-serif;color:black">.</span><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#212121"><br>
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<o:p></o:p></span></p>
<p style="margin:0in"><span style="font-family:"Arial",sans-serif;color:black">We encourage you to test the portal, and we value your feedback on how to make this resource widely useful to the imaging community. If you’d like to receive occasional invites to
participate in user feedback activities, please</span><span class="apple-converted-space"><span style="font-family:"Arial",sans-serif;color:black"> </span></span><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#212121"><a href="https://urldefense.com/v3/__https://airtable.com/apppmytRJXoXYTO9w/shr9pSO9Rhqv3F1kX?prefill_Event=3dem202312&hide_Event=true__;!!Mih3wA!CB7Nk5GhJMqhVh3cMLwiHj3lYuJ-GhyBH-iEZ_PmIiThmY2DTxZxOzLWTXOTQ9WGI9GfxkEAKvWPNJIo58DEZA$" title="https://airtable.com/apppmytRJXoXYTO9w/shr9pSO9Rhqv3F1kX?prefill_Event=3dem202312&hide_Event=true"><span style="font-size:11.0pt;font-family:"Arial",sans-serif;color:#0078D7">let
us know</span></a></span><span style="font-family:"Arial",sans-serif;color:black">.</span><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#212121"><o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p style="margin:0in"><span style="font-family:"Arial",sans-serif;color:black">We’re also planning to launch a machine-learning challenge using datasets within the portal next year to encourage algorithm development, and we’ll share more about this as plans
come together. If you are interested in learning more about the Chan Zuckerberg Imaging Institute, please</span><span class="apple-converted-space"><span style="font-family:"Arial",sans-serif;color:black"> </span></span><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#212121"><a href="https://urldefense.com/v3/__https://info.chanzuckerberg.com/czii-newsletter-sign-up__;!!Mih3wA!CB7Nk5GhJMqhVh3cMLwiHj3lYuJ-GhyBH-iEZ_PmIiThmY2DTxZxOzLWTXOTQ9WGI9GfxkEAKvWPNJIRKM11Qg$" title="https://info.chanzuckerberg.com/czii-newsletter-sign-up"><span style="font-size:11.0pt;font-family:"Arial",sans-serif;color:#0078D7">sign
up for our mailing list</span></a></span><span style="font-family:"Arial",sans-serif;color:black">.</span><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#212121"><o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p style="margin:0in"><span style="font-family:"Arial",sans-serif;color:black">Best regards,</span><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#212121"><o:p></o:p></span></p>
<p style="margin:0in;caret-color: rgb(33, 33, 33);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-stroke-width: 0px;word-spacing:0px">
<span style="font-family:"Arial",sans-serif;color:black">Bridget</span><span style="font-size:12.0pt;font-family:"Aptos",sans-serif;color:#212121"><o:p></o:p></span></p>
<p class="MsoNormal">P.S. Please send replies to <a href="mailto:cryoetdataportal@chanzuckerberg.com">
cryoetdataportal@chanzuckerberg.com</a> ; sending from my own account today as waiting for approval for this new email address
<span style="font-family:"Apple Color Emoji"">😊</span><o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
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<p class="MsoNormal"><b><span style="font-family:"Lato",sans-serif;color:#222222;mso-ligatures:none">__________________________<o:p></o:p></span></b></p>
<p class="MsoNormal"><b><span style="font-family:"Lato",sans-serif;color:#222222;mso-ligatures:none">Bridget Carragher<o:p></o:p></span></b></p>
<p class="MsoNormal"><span style="font-family:"Lato",sans-serif;color:#222222;mso-ligatures:none">Founding Technical Director<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Lato",sans-serif;color:#222222;mso-ligatures:none">Chan Zuckerberg Imaging Institute</span><span style="color:black;mso-ligatures:none"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Lato",sans-serif;color:#222222;mso-ligatures:none"><a href="mailto:bridget.carragher@czbiohub.org"><span style="color:#0563C1">bcarragher@czii.org</span></a></span><span style="color:black;mso-ligatures:none"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="color:black;mso-ligatures:none"><o:p> </o:p></span></p>
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