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<p class="MsoListParagraph" style="margin-left:0in;mso-add-space:auto"><span style="font-size:10.0pt;line-height:105%;font-family:"Arial",sans-serif;color:#333333">Hello CryoEM Researchers,
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:#333333">Pacific Northwest CryoEM Center is offering a mechanism developed to help laboratories with
<b>limited or no cryo-EM resources</b> enter the field of cryo-EM. PNCC's "Screening Access Mechanism" will provide users on-site access to state-of-the-art cryo-EM resources and expertise to carry out sample preparation and optimization under close supervision
of trained cryo-EM specialists. <o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:#333333"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:#333333">Our goal is to help users identify cryo-grid conditions that will be successful for transitioning to data collection activities provided by PNCC’s General Access
mechanism or to establish the technical feasibility and provide guidance on the next states of the project. We hope this new mechanism will enable investigators lacking access to local cryo-EM resources and help jump-start investigators interested in entering
the field of cryo-EM.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:#333333"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:#333333">For more information about our "Screening Access Mechanism", go
<a href="https://urldefense.com/v3/__https:/pncc.labworks.org/access/choose-access-type__;!!OLyWHuc!WRbkzpZk2YzMC6e8cuCMLj79P_Y9slTq5ZshAfmSeZ_UWlYZTAMrpq9zpeRgVi3X_Ug7jJWfiIFu1i6s8tSQEr1PVA$">
here</a>. </span><span style="font-size:10.0pt;font-family:"Arial",sans-serif">Applications are accepted on a monthly basis, with the next deadline for this proposal type being
<b><span style="color:#333333">November 1<sup>st</sup>, </span></b><span style="color:#333333">2023 at 11:59pm (Pacific) in our portal here. Step-by-step instructions on how to submit a proposal to PNCC can be found
</span></span><a href="https://urldefense.com/v3/__https:/pncc.labworks.org/sites/default/files/20220103_Step-by-Step_Submission_Guide.pdf__;!!OLyWHuc!WRbkzpZk2YzMC6e8cuCMLj79P_Y9slTq5ZshAfmSeZ_UWlYZTAMrpq9zpeRgVi3X_Ug7jJWfiIFu1i6s8tTiYiphTA$">here</a><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:#333333">.<o:p></o:p></span></p>
<p class="MsoListParagraphCxSpFirst" style="margin-left:0in;mso-add-space:auto"><span style="font-size:10.0pt;line-height:105%;font-family:"Arial",sans-serif;color:#333333"><o:p> </o:p></span></p>
<p class="MsoListParagraphCxSpLast" style="margin-left:0in;mso-add-space:auto"><span style="font-size:10.0pt;line-height:105%;font-family:"Arial",sans-serif;color:#333333">We request your help by disseminating this information to colleagues who may be interested
in engaging in the field of cryo-EM</span><o:p></o:p></p>
<p class="MsoNormal"><b><span style="color:#E08A32">_________________________<br>
</span></b><span style="font-size:13.0pt">Kjirsten Wheeler<b><br>
</b></span><span style="font-size:9.0pt">PNCC Administrative Coordinator</span><o:p></o:p></p>
<p class="MsoNormal"><b><span style="color:#E08A32">Pacific Northwest</span></b><b><span style="color:#ED7D31">
</span></b><b><span style="color:#5B97C9">Cryo-EM Center<br>
</span></b><span style="font-size:9.0pt">a <b><span style="color:#E08A32">PNNL</span></b> and
<b><span style="color:#5B97C9">OHSU</span></b> affiliation</span><span style="font-size:8.0pt">
<span style="color:blue"> </span></span><a href="https://urldefense.com/v3/__https:/pncc.labworks.org/__;!!Mi0JBg!burdB2N3-jSi-4APwohcbkMgXzrhpmrr-Q_XadX2I6g6qfUKLs-MOS_CSrl8z8tr$"><span style="font-size:8.0pt;color:#0563C1">Website</span></a><span style="font-size:8.0pt">
</span><a href="https://urldefense.com/v3/__https:/twitter.com/CryoEM_PNCC__;!!Mi0JBg!burdB2N3-jSi-4APwohcbkMgXzrhpmrr-Q_XadX2I6g6qfUKLs-MOS_CSvMnTGN3$"><span style="font-size:8.0pt;color:#0563C1">PNCC Twitter</span></a><span style="font-size:9.0pt"><br>
</span><span style="font-size:8.0pt;color:#538135"><br>
</span><a href="mailto:wheelekj@ohsu.edu"><span style="font-size:9.0pt;color:#0563C1">wheelekj@ohsu.edu</span></a><o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
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