<div dir="ltr"><p class="gmail-p1" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0)">We have a Ph.D. studentship available in structure and function of bacteriophages. Applications will be considered from eligible students of any nationality.</p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p1" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0)">White Rose BBSRC DTP: Deciphering the structural and genetic intricacies of bacteriophage interaction with an AMR pathogen</p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p1" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0)">University of Sheffield - White Rose BBSRC Doctoral Training Partnership</p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p1" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0)">PhD Research Project</p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p1" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0)">Directly Funded</p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p1" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0)">Supervisors: Prof G Stafford, Prof P A Bullough, Dr S Mesnage, Dr J Rafferty</p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p1" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0)">Application Deadline: 07 January 2024</p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p1" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0)">Details</p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p1" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0)">Bacteriophage are the most numerous biological entities on our planet; they are viruses that have evolved to exquisitely target bacterial pathogens with which they have co-evolved. This project aims to use a combined structural (Cryo-EM, electron tomography), biochemical (enzymology), microbiological (phage infections, AMR assays) and genetic approaches (variant sequencing) to uncover the mechanisms occurring at the bacterial cell surface during phage killing of the multiply drug-resistant pathogen <i>Enterococcus faecium</i>. The work will uncover the fundamental mechanisms at work at this cross-kingdom viral-bacterial interface and help to pave the way towards the realization of bacteriophage based therapies to treat incurable drug-resistant infections.</p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p1" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0)">You will join a thriving microbiology and structural biology community in Sheffield focussing on AMR pathogens and bacteriophage and join a supportive and stimulating intellectual environment. This project will provide a broad training in phage biology, structural biology as well as basic bioinformatics.</p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p1" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0)">The University of Sheffield and the DTP provides bespoke training programmes and has the highest standards of equality and diversity programmes with its One University pillar.</p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p1" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0)">What is on offer?</p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p1" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0)">This is a core studentship for entry in October 2024. </p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p1" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0)">Join us and you will receive a 4-year, funded PhD programme of research and skills training, with cross-disciplinary supervision, plus a structured programme of cohort-wide training and networking events. A highlight is the annual symposium, which is planned and delivered by students.</p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p1" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0)">A unique part of your training will be the Professional Internships for PhD Students (PIPS), where you will spend three months at a host organisation of your choosing, gaining experience of work in a professional environment, and acquiring transferable skills that will be beneficial in your future career.</p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p1" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0)">How to apply –<span class="gmail-Apple-converted-space"> </span></p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p1" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0)">follow this link <a href="https://urldefense.com/v3/__https://www.whiterose-mechanisticbiology-dtp.ac.uk/standard-studentships-2/__;!!Mih3wA!BlnZ5zfe-TXUexSIGjIqSy9hbwDeZWWlMp6ML__E2_RF6QjTSR3kn1CgTtSFmwH88wgnBkF0iG5eSJI3u_jtEgDSpEcLgw$">https://www.whiterose-mechanisticbiology-dtp.ac.uk/standard-studentships-2/</a></p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p1" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0)">Deadline is midnight Sunday 7th January 2024.</p>
<p class="gmail-p2" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0);min-height:12px"><br></p>
<p class="gmail-p1" style="margin:0px;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:11px;line-height:normal;font-family:"Helvetica Neue";color:rgb(0,0,0)">For informal enquiries, please contact Prof. Per Bullough <a href="mailto:p.bullough@sheffield.ac.uk">p.bullough@sheffield.ac.uk</a>.</p><div><div dir="ltr" class="gmail_signature" data-smartmail="gmail_signature"><div dir="ltr"><div style="font-family:Helvetica;font-size:14px;color:rgb(0,0,0)"><br></div><div style="font-family:Helvetica;font-size:14px;color:rgb(0,0,0)">Prof. Per A. Bullough</div><div style="font-family:Helvetica;font-size:14px;color:rgb(0,0,0)">Harrison Chair of Structural Biology</div><div><font color="#000000" face="Helvetica"><span style="font-size:14px">Lead, Molecular Microbiology; Biochemistry to Disease</span></font><br><font color="#000000" face="Helvetica"><span style="font-size:14px">School of Biosciences</span></font><br><font color="#000000" face="Helvetica"><span style="font-size:14px">University of Sheffield</span></font><br><font color="#000000" face="Helvetica"><span style="font-size:14px">Firth Court</span></font><br><font color="#000000" face="Helvetica"><span style="font-size:14px">Western Bank</span></font><br><font color="#000000" face="Helvetica"><span style="font-size:14px">Sheffield S10 2TN</span></font><br><font color="#000000" face="Helvetica"><span style="font-size:14px">United Kingdom</span></font><br><br><font color="#000000" face="Helvetica"><span style="font-size:14px">Tel: +44 (0)114 222 4245</span></font><br><font color="#000000" face="Helvetica"><span style="font-size:14px">Fax: +44 (0)114 222 2800</span></font><br><a href="mailto:p.bullough@sheffield.ac.uk" style="color:rgb(0,0,0);font-family:Helvetica;font-size:14px" target="_blank">e-mail: p.bullough@sheffield.ac.uk</a><br><font color="#000000" face="Helvetica"><span style="font-size:14px"><a href="https://urldefense.com/v3/__https://www.sheffield.ac.uk/biosciences/research/areas/molecular-microbiology__;!!Mih3wA!BlnZ5zfe-TXUexSIGjIqSy9hbwDeZWWlMp6ML__E2_RF6QjTSR3kn1CgTtSFmwH88wgnBkF0iG5eSJI3u_jtEgB6cpPfAQ$" target="_blank">https://www.sheffield.ac.uk/biosciences/research/areas/molecular-microbiology</a></span></font><br></div><div><font color="#000000" face="Helvetica"><span style="font-size:14px"><a href="https://urldefense.com/v3/__https://www.sheffield.ac.uk/biosciences/people/academic-staff/bullough__;!!Mih3wA!BlnZ5zfe-TXUexSIGjIqSy9hbwDeZWWlMp6ML__E2_RF6QjTSR3kn1CgTtSFmwH88wgnBkF0iG5eSJI3u_jtEgCg82t1IQ$" target="_blank">https://www.sheffield.ac.uk/biosciences/people/academic-staff/bullough</a></span><br></font></div><div><font color="#000000" face="Helvetica"><span style="font-size:14px"><a href="https://urldefense.com/v3/__http://www.floreyinstitute.com/__;!!Mih3wA!BlnZ5zfe-TXUexSIGjIqSy9hbwDeZWWlMp6ML__E2_RF6QjTSR3kn1CgTtSFmwH88wgnBkF0iG5eSJI3u_jtEgDRpL0Tnw$" target="_blank">http://www.floreyinstitute.com/</a></span><br></font></div></div></div></div></div>