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<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="color:black;mso-ligatures:none">Seeking a Postdoctoral Associate to investigate mitochondrial structural and functional disturbances in dopaminergic neurons and organoids
derived from patients with bipolar disorder. Specific details of the position will include:<o:p></o:p></span></p>
<ul type="disc">
<li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;mso-list:l0 level1 lfo1">
<span style="mso-ligatures:none">Investigate how mitochondrial function contributes to dopamine production and release in neurons and organoids derived from patients with bipolar disorder and unaffected individuals.<o:p></o:p></span></li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;mso-list:l0 level1 lfo1">
<span style="mso-ligatures:none">Development of in situ cryo-ET and live-cell imaging approaches to identify the effects of bipolar disorder on mitochondrial structure and dynamics in dopamine neurons.<o:p></o:p></span></li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;mso-list:l0 level1 lfo1">
<span style="mso-ligatures:none">Participate in the development and analysis of novel imaging methodologies to follow mRNA and protein localization in response to cell activity in neurons.<o:p></o:p></span></li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;mso-list:l0 level1 lfo1">
<span style="mso-ligatures:none">Development and writing of one or more annual publications arising from the above research, as well as abstracts to be presented at national and/or international meetings.<o:p></o:p></span></li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;mso-list:l0 level1 lfo1">
<span style="mso-ligatures:none">Present progress on your work on a regular basis in laboratory and departmental meetings.<o:p></o:p></span></li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;mso-list:l0 level1 lfo1">
<span style="mso-ligatures:none">Teach and supervise undergraduate and graduate students as well as a Research Associate who collectively will assist with the research within the laboratory.<o:p></o:p></span></li></ul>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="color:black;mso-ligatures:none">Please email Zachary Freyberg at
<a href="mailto:freyberg@pitt.edu">freyberg@pitt.edu</a> with CV and references.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="color:black;mso-ligatures:none">Qualifications:<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="color:black;mso-ligatures:none">Requirements are a doctorate in Cell Biology, Metabolism, and/or Neurobiology, 4+ years of experience/exposure in live-cell microscopy,
cryo-electron microscopy, and/or metabolism. Additional expertise in the development of molecular biology is preferable. Effective communication and writing skills are also highly preferable.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="color:black;mso-ligatures:none">The University of Pittsburgh is committed to championing all aspects of diversity, equity, inclusion, and accessibility within our community.
This commitment is a fundamental value of the University and is crucial in helping us advance our mission, which includes attracting and retaining diverse workforces. We will continue to create and maintain an environment that allows individuals to discover,
belong, contribute, and grow, while honoring the experiences, perspectives, and unique identities of all.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="color:black;mso-ligatures:none">The University of Pittsburgh is an Affirmative Action/Equal Opportunity Employer and values equality of opportunity, human dignity,
and diversity. EOE, including disability/vets.<o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
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