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<p class="MsoNormal"><span style="font-size:14.0pt;font-family:Helvetica">Postdoctoral Associate positions are immediately available in Professor Tina Izard’s cell adhesion laboratory.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:Helvetica"><o:p> </o:p></span></p>
<p style="margin:0in"><span style="font-size:14.0pt;font-family:Helvetica">The laboratory collaborates with several other laboratories on campus including exciting collaborative and currently active projects with Professors
<o:p></o:p></span></p>
<p style="margin:0in"><span style="font-size:14.0pt;font-family:Helvetica">Kirill Martenmyanov (<a href="https://urldefense.com/v3/__http://www.science.org/doi/10.1126/science.abl4732__;!!Mih3wA!FF4nJoRzQR_SpF2-pmfzU6Qgqem6HFtFMgAb5lraNpwo-X3l9jNM8tYAyYZKBY0Vm7rO240D7J4TU5DJKO0$">www.science.org/doi/10.1126/science.abl4732</a>),
<o:p></o:p></span></p>
<p style="margin:0in"><span style="font-size:14.0pt;font-family:Helvetica">Kendall Nettles (<a href="https://urldefense.com/v3/__https://doi.org/10.1073/pnas.2101657118__;!!Mih3wA!FF4nJoRzQR_SpF2-pmfzU6Qgqem6HFtFMgAb5lraNpwo-X3l9jNM8tYAyYZKBY0Vm7rO240D7J4TmYQStTc$">https://doi.org/10.1073/pnas.210165711</a>),
<o:p></o:p></span></p>
<p style="margin:0in"><span style="font-size:14.0pt;font-family:Helvetica">Susana Valente (<a href="https://urldefense.com/v3/__https://pubmed.ncbi.nlm.nih.gov/30723126__;!!Mih3wA!FF4nJoRzQR_SpF2-pmfzU6Qgqem6HFtFMgAb5lraNpwo-X3l9jNM8tYAyYZKBY0Vm7rO240D7J4TBaX-JJk$">https://pubmed.ncbi.nlm.nih.gov/30723126</a>), and
<o:p></o:p></span></p>
<p style="margin:0in"><span style="font-size:14.0pt;font-family:Helvetica">Luiz Carvalho (<a href="https://urldefense.com/v3/__https://scripps.ufl.edu/profile/carvalho-luiz-pedro/__;!!Mih3wA!FF4nJoRzQR_SpF2-pmfzU6Qgqem6HFtFMgAb5lraNpwo-X3l9jNM8tYAyYZKBY0Vm7rO240D7J4TKK9tXy0$">https://scripps.ufl.edu/profile/carvalho-luiz-pedro/</a>).<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:Helvetica"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:Helvetica">Thus, there are several exciting opportunities for a variety of very interesting projects beyond<o:p></o:p></span></p>
<ul style="margin-top:0in" type="disc">
<li style="margin-top:0in;margin-bottom:0in;mso-list:l0 level1 lfo1"><span style="font-size:14.0pt;font-family:Helvetica">structure-function studies of cytoskeletal proteins that control signaling downstream of adherens junctions and focal adhesions with implications
in cancer and heart diseases<o:p></o:p></span></li></ul>
<p style="margin:0in"><span style="font-size:14.0pt;font-family:Helvetica">and more recently<o:p></o:p></span></p>
<ul style="margin-top:0in" type="disc">
<li style="margin-top:0in;margin-bottom:0in;mso-list:l0 level1 lfo1"><span style="font-size:14.0pt;font-family:Helvetica">structure-function studies of novel
<i>Mycobacterium tuberculosis</i> targets in collaboration with Professor Luiz Carvalho (<a href="https://urldefense.com/v3/__https://scripps.ufl.edu/profile/carvalho-luiz-pedro/__;!!Mih3wA!FF4nJoRzQR_SpF2-pmfzU6Qgqem6HFtFMgAb5lraNpwo-X3l9jNM8tYAyYZKBY0Vm7rO240D7J4TKK9tXy0$">https://scripps.ufl.edu/profile/carvalho-luiz-pedro/</a>).<o:p></o:p></span></li></ul>
<p style="margin:0in"><span style="font-size:14.0pt;font-family:Helvetica"><o:p> </o:p></span></p>
<p style="margin:0in"><span style="font-size:14.0pt;font-family:Helvetica">The laboratory is recognized as a world leader and provides outstanding training in protein biochemistry and structural, molecular, and cellular biology, in a highly dynamic and team-oriented
research program. <o:p></o:p></span></p>
<p style="margin:0in"><span style="font-size:14.0pt;font-family:Helvetica"><o:p> </o:p></span></p>
<p style="margin:0in"><span style="font-size:14.0pt;font-family:Helvetica">Successful candidates will work in a cutting-edge research environment with new state-of-the-art facilities. The laboratory has outstanding facilities for cell biology, molecular biology,
protein expression, purification, and biochemistry, and cryogenic electron microscopy, and protein crystallography. The laboratory has access to a large cast of outstanding cores that facilitate basic research and drug development. The unique infrastructure
includes the application of unique chemical, genomic, proteomic, informatics, and high-throughput screening and engineering tools for the discovery of novel biomolecules.<o:p></o:p></span></p>
<p style="margin:0in"><span style="font-size:14.0pt;font-family:Helvetica"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:Helvetica">Professor Tina Izard is a board member of the South East Regional Collaborative Access Team (SER-CAT) that constructed two beam lines at the Advanced Photon Source (APS) at Argonne National
Laboratory. The SER-CAT beam lines are available for all the synchrotron-related data collection needs for the post-doctoral associates. Professor Izard also designed and installed a HighFlux X-ray diffraction system, specifically a Rigaku MicroMax-007 HF,
a second-generation microfocus rotating anode generator together with a mar345 Image Plate detector. An Osmic VariMax optics system and the Proteros Free Mounting System can be used to control the humidity and to optimize diffraction characteristics, including
resolution, mosaicity, and anisotropy, as well as reduced X-ray background.</span><span style="font-size:14.0pt;font-family:Helvetica;color:black"><o:p></o:p></span></p>
<p style="margin:0in"><span style="font-size:14.0pt;font-family:Helvetica"><o:p> </o:p></span></p>
<p style="margin:0in"><span style="font-size:14.0pt;font-family:Helvetica">Professor Tina Izard recently installed the first 300 kV cryo Atomic Resolution Microscope (cryoARM300) in the Americas (<a href="https://urldefense.com/v3/__https://www.youtube.com/watch?v=xdVxAN8xy1w&feature=youtu.be__;!!Mih3wA!FF4nJoRzQR_SpF2-pmfzU6Qgqem6HFtFMgAb5lraNpwo-X3l9jNM8tYAyYZKBY0Vm7rO240D7J4TdjHUO1k$">https://www.youtube.com/watch?v=xdVxAN8xy1w&feature=youtu.be</a>)
and has plenty of microscope time dedicated to the post-doctoral associate. This state-of-the-art transmission electron microscope is a 300 kV high resolution microscope capable of carrying out cryogenic-electron microscopy studies by providing atomic resolution
for structural studies involving single particle analyses. The transmission electron microscope is equipped with new and improved Gatan K3 direct electron detector camera that has better DQE, larger field of view (24 Megapixels – 5,760 x 4,092) and faster
(3.75 times that of K2 camera). The direct detection devices are exquisitely sensitive, produce high signal to noise images, and are ideal for high-resolution studies.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:Helvetica;color:black"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:Helvetica;color:black">Please apply here
<a href="https://urldefense.com/v3/__https://explore.jobs.ufl.edu/en-us/job/521437__;!!Mih3wA!FF4nJoRzQR_SpF2-pmfzU6Qgqem6HFtFMgAb5lraNpwo-X3l9jNM8tYAyYZKBY0Vm7rO240D7J4Tc8AHpQo$">https://explore.jobs.ufl.edu/en-us/job/521437</a> or
</span><span style="font-size:14.0pt;font-family:Helvetica">send your CV, brief summary of research experience and interests, and names, addresses, e-mail, and telephone numbers of 3 references to Professor Tina Izard (t DOT izard AT ufl DOT edu)<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt;font-family:Helvetica;color:black"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:14.0pt"><o:p> </o:p></span></p>
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