<div dir="ltr"><p class="MsoNormal" style="margin:0in 0in 0.0001pt;text-align:justify;font-size:12pt;font-family:"Times New Roman",serif"><span style="font-family:Arial,sans-serif">Dear 3DEM community,</span></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;text-align:justify;font-size:12pt;font-family:"Times New Roman",serif"><span style="font-family:Arial,sans-serif"><br></span></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;text-align:justify;font-size:12pt;font-family:Calibri,sans-serif"><a name="m_-2894697867845150930_OLE_LINK35"></a><a name="m_-2894697867845150930_OLE_LINK34"><span style="font-family:Arial,sans-serif">Dr. Shiwei Zhu's lab at the Department of Physiology and Biophysics, Case Western Reserve University in Cleveland, Ohio, currently has an immediate postdoctoral position available.</span></a></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;text-align:justify;font-size:12pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif"> </span></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;text-align:justify;font-size:12pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif">The Zhu lab is seeking a postdoctoral training fellow to join our team to investigate the host defense mechanisms and the adaptation of pathogens within host cells. In this exciting opportunity, you will utilize cryo-electron tomography and Aquilos-2 cryo-focused ion beam/scanning electron microscope (cryo-FIB/SEM) <a name="m_-2894697867845150930_OLE_LINK20"></a><a name="m_-2894697867845150930_OLE_LINK19">integrated </a>with an internal cryo-correlative light electron microscope (cryo-CLEM) to visualize crucial biological processes to defend host cells against external threats. Your responsibilities will include: developing imaging pipelines for high-throughput in situ cryo-ET and its applications in studying host-pathogen interactions; reconstituting functional antimicrobial complexes, determining their structures using cryo-electron microscopy/tomography (cryo-EM/ET), and experimentally testing structure-based hypotheses to gain new insights into the molecular mechanisms of antimicrobial complexes.</span></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;text-align:justify;font-size:12pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif"> </span></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;text-align:justify;font-size:12pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif">You will have access to state-of-the-art cryo-EM facilities, including a Glacios TEM for sample screening and Titan Krios microscopes for cryo-ET data collection, through the cryo-EM core at CWRU. You also have full access to cryo-FIB/SEM and cryo-CLEM for in situ cryo-ET studies. For obtaining detailed information, please visit our lab website, <a href="https://urldefense.com/v3/__https://www.shiweizhulab.org/__;!!Mih3wA!B2k1kiYQN9t3k3h_mKqaUJ-zR6mCUbSPS4rp_Vu4q6JY5nL-FIHX7mNoLuq3VThMoF6pec0ptTSirvWf1w$" target="_blank" style="color:rgb(5,99,193)">https://www.shiweizhulab.org</a></span></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;text-align:justify;font-size:12pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif"> </span></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;text-align:justify;font-size:12pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif">Applicants should possess a Ph.D. or equivalent degree in one or more of the following areas: structural biology, biochemistry, biophysics, microbiology, or cell biology. Prior experience in structural biology research is not necessary. To inquire about the position, please email Dr. Zhu (<a href="mailto:shiwei.zhu@case.edu" target="_blank">shiwei.zhu@case.edu</a>) with a cover letter detailing your research interests, a recent CV, and the contact information of two academic referees.</span></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;text-align:justify;font-size:12pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif"> </span></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;text-align:justify;font-size:12pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif">We eagerly anticipate receiving applications from all candidates.</span></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;text-align:justify;font-size:12pt;font-family:Calibri,sans-serif"><br></p><div><div dir="ltr" class="gmail_signature" data-smartmail="gmail_signature"><div dir="ltr"><div>Shiwei Zhu,  Ph.D.</div>Assistant Professor, <div>Department of Physiology and Biophysics<div>Case Western Reserve University</div><div>School of Medicine, Robbins Building E611</div><div>Email: <a href="mailto:shiwei.zhu@case.edu" target="_blank">shiwei.zhu@case.edu</a></div><div><a href="https://urldefense.com/v3/__https://www.shiweizhulab.org__;!!Mih3wA!B2k1kiYQN9t3k3h_mKqaUJ-zR6mCUbSPS4rp_Vu4q6JY5nL-FIHX7mNoLuq3VThMoF6pec0ptTT55g8n9A$" target="_blank">https://www.shiweizhulab.org</a><br></div><div><a href="https://urldefense.com/v3/__https://physiology.case.edu/people/faculty/shiwei-zhu__;!!Mih3wA!B2k1kiYQN9t3k3h_mKqaUJ-zR6mCUbSPS4rp_Vu4q6JY5nL-FIHX7mNoLuq3VThMoF6pec0ptTTBkMa-ww$" target="_blank">https://physiology.case.edu/people/faculty/shiwei-zhu</a><br></div><div><br></div><div><br></div></div><div><br></div></div></div></div></div>