<div dir="ltr"><span id="gmail-docs-internal-guid-8d89b179-7fff-e91e-fcb6-b9efe20c1a5f"><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Dear structural biology community - </span></p><br><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Multiple post-doctoral fellow positions are open in the Cianfrocco laboratory at the University of Michigan (</span><a href="https://urldefense.com/v3/__https://www.lsi.umich.edu/science/our-labs/cianfrocco-lab__;!!Mih3wA!CBN81vhVin32vtaOjLEjPcJO_-hFDZD2ZHQ2jLQqTUTi3ouzlly4KmGlKnaOi_gKRBgrmPQ7tBumZC7wdCB3bw$" style="text-decoration-line:none"><span style="font-size:11pt;font-family:Arial;background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;text-decoration-line:underline;vertical-align:baseline;white-space:pre-wrap">https://www.lsi.umich.edu/science/our-labs/cianfrocco-lab</span></a><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">). Both positions offer huge opportunities for growth and provide cutting-edge instrumentation and collaboration. Please reach out to Mike Cianfrocco if you have questions (</span><a href="mailto:mcianfro@umich.edu" style="text-decoration-line:none"><span style="font-size:11pt;font-family:Arial;background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;text-decoration-line:underline;vertical-align:baseline;white-space:pre-wrap">mcianfro@umich.edu</span></a><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">).</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><br></p><div><span id="gmail-docs-internal-guid-d5e5c066-7fff-f05f-62ff-2c0faf56623e"><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Michael A. Cianfrocco, Ph.D.</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Assistant Professor, Department of Biological Chemistry</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Research Assistant Professor, Life Sciences Institute</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">University of Michigan </span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Pronouns: he, him, his</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><br></p></span></div><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-weight:700;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;text-decoration-line:underline;vertical-align:baseline;white-space:pre-wrap">Methods development in cryo-EM</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">We have an NIH-funded post-doctoral fellow position to work as a part of the Magellon cryo-EM automation project. This position will work within a collaborative grant R01GM143805 with the labs of Gabe Lander (The Scripps Research Institute) and Scott Stagg (Florida State University) to develop the next generation of cryo-EM automation and software tools to enable high-throughput cryo-EM. This position will work at the interface of microscope automation, software development, and end-user experience to streamline cryo-EM.</span></p><br><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-style:italic;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Relevant papers:</span></p><ol style="margin-top:0px;margin-bottom:0px"><li dir="ltr" style="list-style-type:decimal;font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre"><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt" role="presentation"><span style="font-size:11pt;background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Optimized path planning surpasses human efficiency in cryo-EM imaging.</span></p></li></ol><p dir="ltr" style="line-height:1.38;margin-left:36pt;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Li Y*, Fan Q*, …, Cianfrocco MA#, Vos S#. </span></p><p dir="ltr" style="line-height:1.38;margin-left:36pt;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-style:italic;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;text-decoration-line:underline;vertical-align:baseline;white-space:pre-wrap">bioRxiv</span><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap"> 2022.06.17.496614</span></p><ol style="margin-top:0px;margin-bottom:0px" start="2"><li dir="ltr" style="list-style-type:decimal;font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre"><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt" role="presentation"><span style="font-size:11pt;background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">CryoRL: Reinforcement Learning Enables Efficient Cryo-EM Data Collection.</span></p></li></ol><p dir="ltr" style="line-height:1.38;margin-left:36pt;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Fan Q*, Li Y*,..., Vos S#, Cianfrocco MA#.  </span></p><p dir="ltr" style="line-height:1.38;margin-left:36pt;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-style:italic;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;text-decoration-line:underline;vertical-align:baseline;white-space:pre-wrap">arXiv</span><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap"> arXiv:2204.07543 (2022).</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap"> </span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-weight:700;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;text-decoration-line:underline;vertical-align:baseline;white-space:pre-wrap">Mechanisms of kinesin regulation</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">We have multiple NIH-funded post-doctoral fellow positions to determine how kinesin motor proteins are regulated via inhibitory mechanisms and activated by cargo and cargo adapters (R01GM141119). We are building on two publications that mapped out how kinesin motor proteins are inhibited in </span><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-style:italic;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">trans</span><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap"> by kinesin-binding protein and </span><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-style:italic;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">cis</span><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap"> via autoinhibition. The state-of-the-art cryo-EM facility and collaborative research environment will allow post-doctoral fellows to open new doors to regulating cargo trafficking.</span></p><br><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-style:italic;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Relevant papers: </span></p><ol style="margin-top:0px;margin-bottom:0px"><li dir="ltr" style="list-style-type:decimal;font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre"><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt" role="presentation"><span style="font-size:11pt;background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Kinesin-binding protein remodels the kinesin motor to prevent microtubule binding.</span></p></li></ol><p dir="ltr" style="line-height:1.38;margin-left:36pt;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Solon AL*, Tan Z*,…, Ohi R#, Cianfrocco MA#. </span></p><p dir="ltr" style="line-height:1.38;margin-left:36pt;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-style:italic;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;text-decoration-line:underline;vertical-align:baseline;white-space:pre-wrap">Science Advances</span><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap"> 2021 Nov 19;7(47):eabj9812.</span></p><ol style="margin-top:0px;margin-bottom:0px" start="2"><li dir="ltr" style="list-style-type:decimal;font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre"><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt" role="presentation"><span style="font-size:11pt;background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Autoinhibited kinesin-1 adopts a hierarchical folding pattern.</span></p></li></ol><p dir="ltr" style="line-height:1.38;margin-left:36pt;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Tan Z, …, Cianfrocco MA#. </span></p><p dir="ltr" style="line-height:1.38;margin-left:36pt;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-style:italic;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;text-decoration-line:underline;vertical-align:baseline;white-space:pre-wrap">eLife</span><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap"> 2023 12:RP86776</span></p><br><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><u><b><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Cryo-EM at the University of Michigan</span><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap"> </span></b></u></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">The University of Michigan offers state-of-the-art instrumentation and a collaborative training environment for post-doctoral fellows. The Cianfrocco lab has routine access to all cryo-EM instruments on campus (and in our building!): Titan Krios (x2), Talos Arctica, and Glacios. We also have access to an SPT Labtech Chameleon, TFS Aquilos 2, Leica Stellaris cryo-confocal, and two negative stain screening instruments. In addition to instrumentation, the Cianfrocco laboratory has access to high-performance computing and storage at the Life Sciences Institute and through the COSMIC2 science gateway (managed by the lab for the community).</span></p><br><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Post-doctoral fellows will also have access to world-class educational resources, which include an annual cryo-EM data processing workshop (</span><a href="https://urldefense.com/v3/__https://www.lsi.umich.edu/science/centers-technologies/cryo-electron-microscopy/education/michigan-cryo-em-workshops__;!!Mih3wA!CBN81vhVin32vtaOjLEjPcJO_-hFDZD2ZHQ2jLQqTUTi3ouzlly4KmGlKnaOi_gKRBgrmPQ7tBumZC4NTjNnhw$" style="text-decoration-line:none"><span style="font-size:11pt;font-family:Arial;background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;text-decoration-line:underline;vertical-align:baseline;white-space:pre-wrap">https://www.lsi.umich.edu/science/centers-technologies/cryo-electron-microscopy/education/michigan-cryo-em-workshops</span></a><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">) and working with the lab to develop the cryoEDU educational platform (<a href="https://urldefense.com/v3/__http://cryoedu.org__;!!Mih3wA!CBN81vhVin32vtaOjLEjPcJO_-hFDZD2ZHQ2jLQqTUTi3ouzlly4KmGlKnaOi_gKRBgrmPQ7tBumZC6EiHeuyg$">cryoedu.org</a>). </span></p><br><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap"><u><b>University of Michigan Microtubule & Motor Protein Community</b></u></span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Beyond structural biology, the University of Michigan offers a close-knit microtubule and motor protein community that ranges from molecular simulations to biochemistry and structural biology to cell biology with the labs of Morgan DeSantis, Ryoma Ohi, David Sept, and Kristen Verhey. We have weekly group meetings and regular social gatherings. Select collaborative works from our microtubule group include: </span></p><br><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-style:italic;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">[Verhey & Cianfrocco labs]</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Autoinhibited kinesin-1 adopts a hierarchical folding pattern. eLife 2023</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Molecular determinants for α-tubulin methylation by SETD2. J Biol Chem. 2021</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">A kinesin-1 variant reveals motor-induced microtubule damage in cells. Curr Biol. 2022 </span></p><br><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-style:italic;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">[Ohi, Sept, Cianfrocco labs]</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Kinesin-binding protein remodels the kinesin motor to prevent microtubule binding. Sci Adv. 2021</span></p><br><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-style:italic;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">[Ohi, Sept, Cianfrocco, Verhey labs]</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Parthenolide Destabilizes Microtubules by Covalently Modifying Tubulin. Curr Biol. 2021 </span></p><br><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-style:italic;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">[Ohi & Verhey labs]</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Mechanistic Analysis of CCP1 in Generating ΔC2 α-Tubulin in Mammalian Cells and Photoreceptor Neurons. Biomolecules. 2023 </span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">EML2-S constitutes a new class of proteins that recognizes and regulates the dynamics of tyrosinated microtubules. Curr Biol. 2022 </span></p><br><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-style:italic;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">[Sept & Verhey labs]</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:rgb(0,0,0);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline;white-space:pre-wrap">Neck linker docking is critical for Kinesin-1 force generation in cells but at a cost to motor speed and processivity. Elife. 2019 </span></p></span><br class="gmail-Apple-interchange-newline"><div><div dir="ltr" class="gmail_signature" data-smartmail="gmail_signature"><div dir="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