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<a class="ContentPasted0"></a>Dear all,<o:p class="ContentPasted0"> </o:p></p>
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I would like to draw your attention to open postdoctoral researcher positions in my group. We use a diverse set of model systems to study how cell surfaces are engineered to support diverse physiological processes, including tissue homeostasis, cell wall formation,
microbial encapsulation, and biofilm formation. Our work integrates molecular and glycobiology techniques with cryo electron microscopy and crystallography. These classical efforts are complemented with MINFLUX super-resolution nanoscopy and cryo electron
tomography, providing insights into the cellular locations, assemblies, and dynamics of membrane-embedded polysaccharide secretion machineries. Representative publications can be found below.
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Candidates should have a strong background in molecular biology and/or structural biology techniques, be enthusiastic about working in a diverse, multidisciplinary research environment, and have at least one per-reviewed first author publication.
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We are located in Charlottesville, Virginia, about 100 miles from Washington DC, 70 miles from Richmond, and just 25 miles to the Shenandoah National Park.<o:p class="ContentPasted0"> </o:p></p>
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Interested candidates should contact me via email (<a href="mailto:jz3x@virginia.edu" class="ContentPasted0">jz3x@virginia.edu</a>) or apply directly via:
<a href="https://urldefense.com/v3/__https://hhmi.wd1.myworkdayjobs.com/External/job/University-of-Virginia/Postdoctoral-Associate---Zimmer-Lab_R-1271__;!!Mih3wA!DvW3vL6-2D6tfS9KCLdAcg7hfBV-gl-eJTuCz42qHrNBJuFzs8NchfPMjIDxyHhvZWLt8WIwnhUTKtoUuRo$" class="ContentPasted0">
https://hhmi.wd1.myworkdayjobs.com/External/job/University-of-Virginia/Postdoctoral-Associate---Zimmer-Lab_R-1271</a>.<o:p class="ContentPasted0"> </o:p></p>
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Sincerely,</p>
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Jochen</p>
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+++++++++<o:p class="ContentPasted0"> <br>
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<a href="https://urldefense.com/v3/__https://pubmed.ncbi.nlm.nih.gov/36064941/__;!!Mih3wA!DvW3vL6-2D6tfS9KCLdAcg7hfBV-gl-eJTuCz42qHrNBJuFzs8NchfPMjIDxyHhvZWLt8WIwnhUT2GLBIDE$" class="ContentPasted0">Molecular basis for polysaccharide recognition and modulated ATP hydrolysis by the O antigen ABC transporter.
</a><span class="docsum-authors ContentPasted0">Spellmon N, Muszyński A, Górniak I, Vlach J, Hahn D, Azadi P, Zimmer J.</span>
<span class="docsum-journal-citation ContentPasted0">Nat Commun. 2022 Sep 5;13(1):5226</span><o:p class="ContentPasted0"> </o:p></p>
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<a href="https://urldefense.com/v3/__https://pubmed.ncbi.nlm.nih.gov/35355017/__;!!Mih3wA!DvW3vL6-2D6tfS9KCLdAcg7hfBV-gl-eJTuCz42qHrNBJuFzs8NchfPMjIDxyHhvZWLt8WIwnhUTSlzAx94$" class="ContentPasted0">Structure, substrate recognition and initiation of hyaluronan synthase.
</a><span class="docsum-authors ContentPasted0">Maloney FP, Kuklewicz J, Corey RA, Bi Y, Ho R, Mateusiak L, Pardon E, Steyaert J, Stansfeld PJ,
<span style="mso-bidi-font-weight:bold" class="ContentPasted0">Zimmer J.</span></span>
<span class="docsum-journal-citation ContentPasted0">Nature. 2022 Apr;604(7904):195-201</span><o:p class="ContentPasted0"> </o:p></p>
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<p class="MsoNormal ContentPasted0" style="margin:0in 0in 0.0001pt;font-size:12pt;font-family:"Times New Roman", serif;margin-right:0in;margin-left:0in">
<a href="https://urldefense.com/v3/__https://pubmed.ncbi.nlm.nih.gov/33712813/__;!!Mih3wA!DvW3vL6-2D6tfS9KCLdAcg7hfBV-gl-eJTuCz42qHrNBJuFzs8NchfPMjIDxyHhvZWLt8WIwnhUT60F_dLw$" class="ContentPasted0">Molecular organization of the E. coli cellulose synthase macrocomplex.
</a><span class="docsum-authors ContentPasted0">Acheson JF, Ho R, Goularte NF, Cegelski L,
<span style="mso-bidi-font-weight:bold" class="ContentPasted0">Zimmer J.</span></span>
<span class="docsum-journal-citation ContentPasted0">Nat Struct Mol Biol. 2021 Mar;28(3):310-318</span><o:p class="ContentPasted0"> </o:p></p>
<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:12pt;font-family:"Times New Roman", serif;margin-right:0in;margin-left:0in">
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<p class="MsoNormal ContentPasted0" style="margin:0in 0in 0.0001pt;font-size:12pt;font-family:"Times New Roman", serif;margin-right:0in;margin-left:0in">
<a href="https://urldefense.com/v3/__https://pubmed.ncbi.nlm.nih.gov/32646917/__;!!Mih3wA!DvW3vL6-2D6tfS9KCLdAcg7hfBV-gl-eJTuCz42qHrNBJuFzs8NchfPMjIDxyHhvZWLt8WIwnhUTIeniOPw$" class="ContentPasted0">Architecture of a catalytically active homotrimeric plant cellulose synthase complex.
</a><span class="docsum-authors ContentPasted0">Purushotham P, Ho R, <span style="mso-bidi-font-weight:bold" class="ContentPasted0">
Zimmer J.</span></span> <span class="docsum-journal-citation ContentPasted0">Science. 2020 Aug 28;369(6507):1089-1094</span><o:p class="ContentPasted0"> </o:p></p>
<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:12pt;font-family:"Times New Roman", serif;margin-right:0in;margin-left:0in">
<span style="font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman""><o:p class="ContentPasted0"> </o:p></span></p>
<p class="MsoNormal ContentPasted0" style="margin:0in 0in 0.0001pt;font-size:12pt;font-family:"Times New Roman", serif;margin-right:0in;margin-left:0in">
<a href="https://urldefense.com/v3/__https://pubmed.ncbi.nlm.nih.gov/29320481/__;!!Mih3wA!DvW3vL6-2D6tfS9KCLdAcg7hfBV-gl-eJTuCz42qHrNBJuFzs8NchfPMjIDxyHhvZWLt8WIwnhUTd3-XPfg$" class="ContentPasted0">Architecture of a channel-forming O-antigen polysaccharide ABC transporter.
</a><span class="docsum-authors ContentPasted0">Bi Y, Mann E, Whitfield C, <span style="mso-bidi-font-weight:bold" class="ContentPasted0">
Zimmer J.</span></span> <span class="docsum-journal-citation ContentPasted0">Nature. 2018 Jan 18;553(7688):361-365</span><o:p class="ContentPasted0"> </o:p></p>
<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:12pt;font-family:"Times New Roman", serif;margin-right:0in;margin-left:0in">
<span style="font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman""><o:p class="ContentPasted0"> </o:p></span></p>
<p class="MsoNormal ContentPasted0" style="margin:0in 0in 0.0001pt;font-size:12pt;font-family:"Times New Roman", serif;margin-right:0in;margin-left:0in">
<a href="https://urldefense.com/v3/__https://pubmed.ncbi.nlm.nih.gov/26958837/__;!!Mih3wA!DvW3vL6-2D6tfS9KCLdAcg7hfBV-gl-eJTuCz42qHrNBJuFzs8NchfPMjIDxyHhvZWLt8WIwnhUTYvnY5SE$" class="ContentPasted0">Observing cellulose biosynthesis and membrane translocation in crystallo.
</a><span class="docsum-authors ContentPasted0">Morgan JL, McNamara JT, Fischer M, Rich J, Chen HM, Withers SG,
<span class="ContentPasted0">Zimmer J.</span></span> <span class="docsum-journal-citation ContentPasted0">
Nature. 2016 Mar 17;531(7594):329-34</span><o:p class="ContentPasted0"> </o:p></p>
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<p style="margin-top:0; margin-bottom:0"><span style="font-size:10pt">*******************************</span></p>
<span style="font-size:10pt"></span>
<p style="margin-top:0; margin-bottom:0"><span style="font-size: 11pt; font-family: Calibri;">Jochen Zimmer, D. Phil.</span></p>
<span style="font-size:10pt"></span><span style="font-family: Calibri; font-size: 11pt;"></span>
<p style="margin-top:0; margin-bottom:0"><span style="font-size: 11pt; font-family: Calibri;">Investigator, Howard Hughes Medical Institute</span><span style="font-size:10pt"><br>
</span></p>
<p style="margin-top:0; margin-bottom:0"><span style="font-size: 11pt; font-family: Calibri;">University of Virginia</span></p>
<span style="font-size:10pt"></span><span style="font-family: Calibri; font-size: 11pt;"></span>
<p style="margin-top:0; margin-bottom:0"><span style="font-size: 11pt; font-family: Calibri;">Molecular Physiology & Biol. Physics</span></p>
<span style="font-size:10pt"></span><span style="font-family: Calibri; font-size: 11pt;"></span>
<p style="margin-top:0; margin-bottom:0"><span style="font-size: 11pt; font-family: Calibri;">480 Ray C. Hunt Dr.</span></p>
<span style="font-size:10pt"></span><span style="font-family: Calibri; font-size: 11pt;"></span>
<p style="margin-top:0; margin-bottom:0"><span style="font-size: 11pt; font-family: Calibri;">Snyder Bldg. #380</span></p>
<span style="font-size:10pt"></span><span style="font-family: Calibri; font-size: 11pt;"></span>
<p style="margin-top:0; margin-bottom:0"><span style="font-size: 11pt; font-family: Calibri;">Charlottesville, VA 22908, USA</span></p>
<span style="font-size:10pt"></span><span style="font-family: Calibri; font-size: 11pt;"></span>
<p style="margin-top:0; margin-bottom:0"><span style="font-size: 11pt; font-family: Calibri;">Phone: +1 434 243 6506</span></p>
<p style="margin-top:0; margin-bottom:0"><span style="font-size:10pt"><a href="https://urldefense.com/v3/__https://jochenzimmer.faculty.virginia.edu/__;!!Mih3wA!DvW3vL6-2D6tfS9KCLdAcg7hfBV-gl-eJTuCz42qHrNBJuFzs8NchfPMjIDxyHhvZWLt8WIwnhUTze5R8gQ$"><span style="font-family: Calibri; font-size: 11pt;">https://jochenzimmer.faculty.virginia.edu/</span></a><br>
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