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<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt">Dear all, <o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt">The first email went too fast...sorry all<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><span lang="EN-US" style="font-size:11.0pt">We have an open position for a postdoc to solve the structure of the centriole using cryo-tomography<o:p></o:p></span></b></p>
<p class="MsoNormal"><b><span lang="EN-US" style="font-size:11.0pt"><o:p> </o:p></span></b></p>
<p class="MsoNormal"><b><span lang="EN-US" style="font-size:11.0pt">More info here :
<a href="https://urldefense.com/v3/__https://cellbio.unige.ch/research/guichard-hamel/job/__;!!Mih3wA!H8bVM16hRBmLEeVYvkk9RawHSPgVi387IdtQam3mzvmrzM-yLzFCGsHtuwYceriIfThbsnCoCgNSzd8WkkNpSAg3ziWd$">https://cellbio.unige.ch/research/guichard-hamel/job/</a><o:p></o:p></span></b></p>
<p class="MsoNormal"><b><span lang="EN-US" style="font-size:11.0pt"><o:p> </o:p></span></b></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt">Postdoc position is limited to 36 months. The position is available from
<b>March 2023 </b>onwards or later depending on the candidate's availability.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt">Centrioles are among the largest macromolecular assemblies within a cell. These barrel-shaped molecular structures, made of nine microtubule triplets of 450 nm long, are at the center of fundamental
cellular processes where they are subjected to external forces that they must resist. Recently, we identified a helical inner scaffold, a protein complex that covers 70% of the inner surface of the centriolar barrel, providing a structural basis for centriole
integrity. However, the molecular structure and topology underlying its crucial function remains largely unknown due to the complexity of the centriole architecture. The project aims at providing an atomic structure of the inner scaffold using cutting-edge
cryo-tomography. We expect results stemming from this work to provide a major advance in the understanding of the inner scaffold structure and consequently, of the mechanisms underlying centriole assembly and function.
</span><span style="font-size:11.0pt"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt">Work will include collaborative research at the national level with the Electron Microscopy facilty at UNIL
<a href="https://urldefense.com/v3/__https://wp.unil.ch/emf/__;!!Mih3wA!H8bVM16hRBmLEeVYvkk9RawHSPgVi387IdtQam3mzvmrzM-yLzFCGsHtuwYceriIfThbsnCoCgNSzd8WkkNpSD4E3CBl$">https://wp.unil.ch/emf/</a> and the Dubochet center for Imaging (Geneva/Lausanne/Bern):
</span><span lang="EN-GB" style="font-size:11.0pt"><a href="https://urldefense.com/v3/__https://www.dci-lausanne.org/__;!!Mih3wA!H8bVM16hRBmLEeVYvkk9RawHSPgVi387IdtQam3mzvmrzM-yLzFCGsHtuwYceriIfThbsnCoCgNSzd8WkkNpSGYb4Jws$">https://www.dci-lausanne.org/</a></span><span style="font-size:11.0pt"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><span lang="EN-US" style="font-size:11.0pt">Your profile</span></b><span style="font-size:11.0pt"><o:p></o:p></span></p>
<ul style="margin-top:0cm" type="disc">
<li class="MsoNormal" style="mso-list:l0 level1 lfo1"><span lang="EN-US" style="font-size:11.0pt">PhD or equivalent academic degree in Biochemistry</span><span style="font-size:11.0pt">,
</span><span lang="EN-US" style="font-size:11.0pt">Physics or Cell Biology with a strong background in imaging processing</span><span style="font-size:11.0pt"><o:p></o:p></span></li></ul>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt">If you are interested, please contact me (<a href="mailto:paul.guichard@unige">paul.guichard@unige</a>) and Virginie Hamel (<a href="mailto:Virginie.hamel@unige.ch">Virginie.hamel@unige.ch</a>)<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt">Best, <o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt">Paul<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
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