<html><head><meta http-equiv="Content-Type" content="text/html; charset=utf-8"></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class="">Dear all,<div class=""><br class=""></div><div class="">We are looking for a cryo-EM scientist to participate in method development at the Ernst-Ruska Centre in Juelich (Germany): </div><div class=""><a href="https://www.fz-juelich.de/en/careers/jobs/2022-124" class="">https://www.fz-juelich.de/en/careers/jobs/2022-124</a></div><div class=""><br class=""></div><div class="">The Ernst Ruska-Centre for Microscopy and Spectroscopy with Electrons (ER-C) at the Forschungszentrum Jülich houses some of the world's most advanced electron microscopes and tools for nanocharacterisation. Our scientific research combines current issues in condensed matter physics and cryo-EM on biomacromolecules with the aim of advancing electron microscopy methods. Under one roof, the ER-C has a total of 15 electron microscopes including the PICO FEI Titan with a point resolution of 0.5 Å. The facility has been extended with state-of-the-art cryo-microscopes ThermoFisher Titan Krios, Talos Arctica both equipped with a Bioquantum K3 and Talos 120 as well as FIB-SEM Aquilos 2. At the Ernst Ruska-Centre for Microscopy and Spectroscopy with Electrons - Structural Biology (<a href="https://go.fzj.de/erc3-ibi6" class="">https://go.fzj.de/erc3-ibi6</a>) we investigate the structural and molecular mechanism of membrane biology processes and push the development of cryo-EM related methodology. Our campus in Jülich hosts a vibrant electron microscopy, biophysics and structural biology community.</div><div class=""><br class=""></div><div class="">Your tasks can include:</div><div class=""><div class="">- Develop new acquisition schemes and workflows based on novel hardware to advance low-dose cryo-EM techniques</div><div class="">- Improve sample handling workflows focusing on single-particle and/or tomography data collection combined with CLEM/FIB-SEM approaches</div><div class="">- Support data acquisition and evaluation for in-house and external users on novel hardware, with the following possible focus areas: 3D image processing of single-particle and/or tomography data and/or FIB-SEM operation for the preparation of cryo-FIB lamellae of vitrified cells</div><div class="">- Improving methodology for high-resolution cryo-EM structure determination at the ER-C-3 for structural biology</div></div><div class=""><br class=""></div><div class="">Feel free to contact me if you have any further questions.</div><div class=""><br class=""></div><div class=""><div class="">Best wishes,</div><div class=""><br class=""></div><div class=""><br class=""></div><div class="">Carsten</div></div><div class=""><div class="">_____________________________________________________________</div><div class="">Prof. Dr. Carsten Sachse </div><div class=""><br class=""></div><div class="">Forschungszentrum Jülich GmbH </div><div class="">Ernst-Ruska Centre for Microscopy and Spectroscopy with Electrons / ER-C-3 Structural Biology</div><div class="">Institute for Biological Information Processing / IBI-6 Cellular Structural Biology</div><div class="">Wilhem-Johnen-Straße, 52425 Jülich, Germany</div><div class=""><a href="https://go.fzj.de/erc3-ibi6" class="">https://go.fzj.de/erc3-ibi6</a> </div><div class=""><a href="http://sachse.fz-juelich.de" class="">http://sachse.fz-juelich.de</a> </div><div class=""><a href="https://twitter.com/SachseGroup" class="">https://twitter.com/SachseGroup</a></div><div class="">Phone: +49 2461 61 2030</div><div class=""><a href="mailto:c.sachse@fz-juelich.de" class="">Email: c.sachse@fz-juelich.de</a><span class="Apple-tab-span" style="white-space:pre"> </span></div><div class=""><br class=""></div></div><div class=""><br class=""></div></body></html>