<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:dt="uuid:C2F41010-65B3-11d1-A29F-00AA00C14882" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40">
<head>
<meta http-equiv="Content-Type" content="text/html; charset=us-ascii">
<meta name="Generator" content="Microsoft Word 15 (filtered medium)">
<style><!--
/* Font Definitions */
@font-face
{font-family:"Cambria Math";
panose-1:2 4 5 3 5 4 6 3 2 4;}
@font-face
{font-family:Calibri;
panose-1:2 15 5 2 2 2 4 3 2 4;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{margin:0in;
font-size:11.0pt;
font-family:"Calibri",sans-serif;}
a:link, span.MsoHyperlink
{mso-style-priority:99;
color:#0563C1;
text-decoration:underline;}
span.EmailStyle17
{mso-style-type:personal-compose;
font-family:"Calibri",sans-serif;
color:windowtext;}
.MsoChpDefault
{mso-style-type:export-only;
font-family:"Calibri",sans-serif;}
@page WordSection1
{size:8.5in 11.0in;
margin:1.0in 1.0in 1.0in 1.0in;}
div.WordSection1
{page:WordSection1;}
--></style><!--[if gte mso 9]><xml>
<o:shapedefaults v:ext="edit" spidmax="1026" />
</xml><![endif]--><!--[if gte mso 9]><xml>
<o:shapelayout v:ext="edit">
<o:idmap v:ext="edit" data="1" />
</o:shapelayout></xml><![endif]-->
</head>
<body lang="EN-US" link="#0563C1" vlink="#954F72" style="word-wrap:break-word">
<div class="WordSection1">
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><span style="color:#222222">Hello CryoEM Researchers,<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto">Pacific Northwest CryoEM Center is offering a new mechanism developed to help laboratories with
<b><u>limited or no cryo-EM</u></b> resources enter the field of cryo-EM. PNCC's "Screening Access Mechanism" will provide users on-site access to state-of-the-art cryo-EM resources and expertise to carry out sample preparation and optimization under close
supervision of trained cryo-EM specialists. <span style="color:#222222"><o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto">Our goal is to help users identify cryo-grid conditions that will be successful for transitioning to data collection activities provided by PNCC’s General Access mechanism or to
establish the technical feasibility and provide guidance on the next states of the project. We hope this new mechanism will enable investigators lacking access to local cryo-EM resources and help jump-start investigators interested in entering the field of
cryo-EM.<o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto">For more information about our "Screening Access Mechanism", go <span style="color:#222222"><a href="https://urldefense.com/v3/__https://gcc02.safelinks.protection.outlook.com/?url=https*3A*2F*2Fpncc.labworks.org*2Faccess*2Fchoose-access-type&data=05*7C01*7Clauren.vega*40pnnl.gov*7C543e0140a4b8492f4f1a08da4fb12eeb*7Cd6faa5f90ae240338c0130048a38deeb*7C0*7C0*7C637909919691296301*7CUnknown*7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0*3D*7C3000*7C*7C*7C&sdata=R1THChboCp9xt4yZRB9pKzJVcm0DMHEE2fMmwl*2B6i*2BQ*3D&reserved=0__;JSUlJSUlJSUlJSUlJSUlJSUlJSUlJSU!!Mih3wA!EKfXJa13yK_IMrzh4WROk-OLjHGR9aTR2Xm6r-DsCVQyCgGYSXkgI3vNOZVBXnxBu2_IWxvE1NfBfuynswdy1CmoBg$" target="_blank">here</a></span>.
The next application deadline for this new proposal type is August 1<sup>st</sup> at 11:59pm (Pacific) in our portal <span style="color:#222222"><a href="https://urldefense.com/v3/__https://gcc02.safelinks.protection.outlook.com/?url=https*3A*2F*2Fpnccportal.labworks.org*2F&data=05*7C01*7Clauren.vega*40pnnl.gov*7C543e0140a4b8492f4f1a08da4fb12eeb*7Cd6faa5f90ae240338c0130048a38deeb*7C0*7C0*7C637909919691296301*7CUnknown*7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0*3D*7C3000*7C*7C*7C&sdata=kHN1lfGwtmyPftrV81pcj2fEj8y3QbvFT6bji8L1ri8*3D&reserved=0__;JSUlJSUlJSUlJSUlJSUlJSUlJSU!!Mih3wA!EKfXJa13yK_IMrzh4WROk-OLjHGR9aTR2Xm6r-DsCVQyCgGYSXkgI3vNOZVBXnxBu2_IWxvE1NfBfuynsweUrWDBoQ$" target="_blank">here</a></span>.<o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto">We request your help by disseminating this information to colleagues who may be interested in engaging in the field of cryo-EM!<o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto">----------------------<o:p></o:p></p>
<p class="MsoNormal" style="background:white"><span style="color:black">Additionally, come swing by our exhibitor booths in Portland, OR at
<a href="https://urldefense.com/v3/__https://www.acameeting.com/__;!!Mih3wA!EKfXJa13yK_IMrzh4WROk-OLjHGR9aTR2Xm6r-DsCVQyCgGYSXkgI3vNOZVBXnxBu2_IWxvE1NfBfuynswe5-CgSMw$">ACA</a> and <a href="https://urldefense.com/v3/__https://www.microscopy.org/MandM/2022/__;!!Mih3wA!EKfXJa13yK_IMrzh4WROk-OLjHGR9aTR2Xm6r-DsCVQyCgGYSXkgI3vNOZVBXnxBu2_IWxvE1NfBfuynsweVYUbMSA$">
M&M</a>, booths 107 and 1046, respectively. Representatives from all the CryoEM National Centers will be there to visit if you want to talk in person!<b><u>
</u></b></span><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto">Regards,<br>
<b><span style="color:#E08A32">_________________________<br>
</span></b><span style="font-size:13.0pt">Lauren B. Vega<b><br>
</b></span><span style="font-size:9.0pt">PNCC Project Coordinator</span><o:p></o:p></p>
<p class="MsoNormal"><b><span style="color:#E08A32">Pacific Northwest</span><span style="color:#ED7D31">
</span><span style="color:#5B97C9">Cryo-EM Center<br>
</span></b><span style="font-size:8.0pt;color:blue"> </span><span style="font-size:9.0pt">a
<b><span style="color:#E08A32">PNNL</span></b> and <b><span style="color:#5B97C9">OHSU</span></b> affiliation</span><span style="font-size:8.0pt">
<span style="color:blue"> </span></span><a href="https://urldefense.com/v3/__https://pncc.labworks.org/__;!!Mih3wA!EKfXJa13yK_IMrzh4WROk-OLjHGR9aTR2Xm6r-DsCVQyCgGYSXkgI3vNOZVBXnxBu2_IWxvE1NfBfuynsweguHAuIg$"><span style="font-size:8.0pt">Website</span></a><span style="font-size:8.0pt">
</span><a href="https://urldefense.com/v3/__https://pnccportal.labworks.org/Portal__;!!Mih3wA!EKfXJa13yK_IMrzh4WROk-OLjHGR9aTR2Xm6r-DsCVQyCgGYSXkgI3vNOZVBXnxBu2_IWxvE1NfBfuynswc1Yzp-fQ$"><span style="font-size:8.0pt">Portal</span></a>
<a href="https://urldefense.com/v3/__https://twitter.com/CryoEM_PNCC__;!!Mih3wA!EKfXJa13yK_IMrzh4WROk-OLjHGR9aTR2Xm6r-DsCVQyCgGYSXkgI3vNOZVBXnxBu2_IWxvE1NfBfuynswdGh6HdJA$"><span style="font-size:8.0pt">PNCC Twitter</span></a><span style="font-size:9.0pt"><br>
</span><span style="font-size:8.0pt;color:#538135"><br>
</span><a href="mailto:Lauren.Vega@PNNL.gov"><span style="font-size:9.0pt">Lauren.Vega@PNNL.gov</span></a><span style="font-size:9.0pt"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:9.0pt">1 – 509 – 372 – 4382<o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
</div>
</body>
</html>