<div dir="ltr"><p class="MsoNormal" style="margin:0in;font-size:12pt;font-family:"Times New Roman",serif"><span style="font-size:10.5pt;font-family:"Avenir Book";color:black;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">Dear all,</span><span style="font-size:10.5pt;font-family:"Avenir Book";background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"></span></p>

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<p class="MsoNormal" style="margin:0in;font-size:12pt;font-family:"Times New Roman",serif"><span style="font-size:10.5pt;font-family:"Avenir Book"">I’m looking for a talented and highly motivated postdoctoral fellow to join my group in the Department of Structural
Biology at Genentech to study the function and regulation of macromolecular
assemblies important in fundamental cellular processes and human disease. </span></p>

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<p class="MsoNormal" style="margin:0in;font-size:12pt;font-family:"Times New Roman",serif"><span style="font-size:10.5pt;font-family:"Avenir Book"">The position is available
immediately and fully funded for up to four years. The postdoc will have the unique
opportunity to work in a highly collaborative research environment on diverse
projects such as investigating T cell receptor signaling and the regulation of
kinetochore assembly and function. The postdoc will be able to independently
pursue projects and grow their expertise in X-ray crystallography and <span style="color:black;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">cryo-EM, with</span>
access to state-of-the-art lab equipment, high resolution cryo-EM technology
and a virtually unlimited computer cluster for data processing<span style="color:black;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">. </span></span></p>

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<p class="MsoNormal" style="margin:0in;font-size:12pt;font-family:"Times New Roman",serif"><span style="font-size:10.5pt;font-family:"Avenir Book";color:black;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">T</span><span style="font-size:10.5pt;font-family:"Avenir Book"">he Department of Structural
Biology at Genentech is a scientifically rich and highly stimulating research
environment that has a strong track record in mentoring postdocs and collaborating
with other research groups at Genentech and in the academic community. </span></p>

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<p class="MsoNormal" style="margin:0in;font-size:12pt;font-family:"Times New Roman",serif"><b><span style="font-size:10.5pt;font-family:"Avenir Book";color:black;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><u>Who you are:</u></span></b></p><p class="MsoNormal" style="margin:0in"></p><ul style=""><li style=""><span style="font-size:10.5pt;font-family:"Avenir Book";color:black">Completed or in the last year of a Ph.D. in
structural biology, biochemistry or a related field of research.</span></li><li style=""><span style="font-variant-numeric:normal;font-variant-east-asian:normal;font-stretch:normal;font-size:7pt;line-height:normal;font-family:"Times New Roman""> </span><span style="font-size:10.5pt;font-family:"Avenir Book";color:black">Demonstrated expertise in protein
purification, biophysical characterization and structure determination by X-ray
crystallography and/or single-particle cryoEM of multi-protein complexes as
shown by a strong record of first-author publications in high quality journals.</span></li><li style=""><span style="font-size:10.5pt;font-family:"Avenir Book";color:black">Experience in protein engineering, biophysical
characterization methods for protein-protein and protein-nucleic acid
interactions, such as surface-plasmon resonance (SPR), Isothermal Titration
Calorimetry (ITC), or bio-layer interferometry (BLI) and i<i>n vitro</i> assay
development will be beneficial.</span><p class="MsoNormal" style="margin:0in 0in 0in 60pt;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial;font-size:12pt;font-family:"Times New Roman",serif"><span style="font-size:10.5pt;font-family:"Avenir Book""></span></p></li><li style=""><span style="font-family:"Avenir Book";font-size:10.5pt;color:black">Self-motivated and detail-oriented, driven to
solve complex scientific problems independently and in a collaborative
environment.</span><br></li><li style=""><font face="arial, sans-serif" style=""><span style="font-variant-numeric:normal;font-variant-east-asian:normal;font-stretch:normal;line-height:normal"> </span></font><span style="font-size:10.5pt;font-family:"Avenir Book";color:black">Strong oral and written communication
skills are required.</span></li></ul>

<p class="MsoNormal" style="margin:0in;font-size:12pt;font-family:"Times New Roman",serif"><i style=""><span style="font-size:10.5pt;font-family:"Avenir Book";color:black;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><b><u>If interested, please contact me directly (dimitrova.yoana at
<a href="https://urldefense.com/v3/__http://gene.com__;!!Mih3wA!HNxWo-xyaBRRj_n7RyqbwAdMxbzqFQMfoiTkDxnnYX2FHPqtWRDg920vW_XysLDxhvg2ZOevpBlS4IlmFQDTDHXBzVE$">gene.com</a>) and include a copy of your CV.</u></b></span></i><b><i><span style="font-size:10.5pt;font-family:"Avenir Book";background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"></span></i></b></p>

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<p class="MsoNormal" style="margin:0in;font-size:12pt;font-family:"Times New Roman",serif"><span style="font-size:10.5pt;font-family:"Avenir Book"">The Genentech Postdoctoral Program
is unique in the pharmaceutical industry with a vibrant community of mentors and
fellows. <b><span style="color:black;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">More
Information about the Genentech Postdoctoral Program:<br>
</span></b></span><span style="font-size:10.5pt;font-family:"Avenir Book""><a href="https://urldefense.com/v3/__http://www.gene.com/careers/academic-programs/postdocs__;!!Mih3wA!HNxWo-xyaBRRj_n7RyqbwAdMxbzqFQMfoiTkDxnnYX2FHPqtWRDg920vW_XysLDxhvg2ZOevpBlS4IlmFQDTN6xaPpk$" style="color:rgb(5,99,193)"><span style="background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">http://www.gene.com/careers/academic-programs/postdocs</span></a></span><span style="font-size:10.5pt;font-family:"Avenir Book";background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"></span></p>

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<p class="MsoNormal" style="margin:0in;font-size:12pt;font-family:"Times New Roman",serif"><span style="font-size:10.5pt;font-family:"Avenir Book"">Best regards,</span></p>

<span style="font-size:10.5pt;font-family:"Avenir Book"">Yoana Dimitrova</span><br clear="all"><div><br></div>-- <br><div dir="ltr" class="gmail_signature" data-smartmail="gmail_signature"><div dir="ltr"><div><span style="font-size:12.8px"><font color="#444444"><b>Yoana Dimitrova</b></font></span></div><div dir="ltr"><span style="color:rgb(136,136,136);font-size:12.8px">Principal Scientist </span><br style="color:rgb(136,136,136);font-size:12.8px"><span style="color:rgb(136,136,136);font-size:12.8px">Genentech, Department of Structural Biology</span></div><div dir="ltr"><font color="#888888"><span style="font-size:12.8px">1 DNA Way,</span></font><span style="color:rgb(136,136,136);font-size:12.8px"> </span><span style="color:rgb(136,136,136);font-size:12.8px">MS: 27</span><div style="color:rgb(136,136,136);font-size:12.8px"><div>South San Francisco, CA 94080</div></div><div style="color:rgb(136,136,136);font-size:12.8px">(cell) 650 534 5216 <br></div></div></div></div></div>