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<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal">Dear all,</span></p>
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<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal">We are happy to announce the 2022 Icknield Workshop on model building and refinement, to be
held from the 6<span><sup>th</sup> to</span> 9th September 2022. This course is largely aimed at structural biologists with high/medium resolution EM maps for modelling building and refinement. This four-day course (6th-9th September) will host some of the
leading software developers and provide ample contact time to allow delegates to discuss their data in detail alongside traditional lectures and tutorials.
</span><span style="color:rgb(33, 33, 33) !important;font-size:11pt;font-family:Arial;background-color:white !important;line-height:normal">This is a comprehensive course for EM model building covering advanced use of ARP/wARP, Buccaneer, CCP-EM, Coot, FlexEM,
ISOLDE, LocScale, MolProbity, Refmac, Privateer and new validation tools. </span>
<span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal">It will cover all aspects of modelling building including: map optimisation, automated model building, medium resolution refinement, high resolution refinement,
interactive refinement, validation and deposition.</span></p>
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<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal">The course will be held at the RAL / Diamond campus, Harwell, UK, site of the eBIC national
facility. Registration fee is £360.00 and we will provide food and three nights accommodation. Delegates are asked to meet their own travel costs.</span></p>
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<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal">The course is limited to 20 delegates which will be selected from all applicants. A maximum
of 40 applicants can register interest. <br>
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<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal"></span></p>
<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(33, 33, 33) !important;font-size:11pt;background-color:white !important;line-height:normal">Registration for the workshop will close when all registration places are taken</span><span style="font-size:11pt;line-height:normal">
and the 20 successful applicants will be informed the following week. Please allow 10-15 mins to fill in the registration details.</span></p>
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<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="font-size:11pt;line-height:normal">* Registration:</span></p>
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<div style="color:black !important;font-size:12pt"><a href="https://urldefense.com/v3/__https://cvent.me/42xnY9__;!!Mih3wA!FECYFrFcZ1zLd2iXpFHaabT1MX3mIIYYU37FRgaKyZ-1gwc5YmKLdbLVxho0pkOfgcJ9TDc8lI5N_xwJBS8uaGNczG_kWo5o$" target="_blank" rel="noopener noreferrer" data-auth="NotApplicable" data-linkindex="0">https://cvent.me/42xnY9</a></div>
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<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal">* Confirmed tutors / topics:</span></p>
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<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal">Arjen Jakobi, Alok Bharadwaj (TU Delft) : LocScale</span></p>
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<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal">Kevin Cowtan, Soon Wen Hoh (University of York) : Buccaneer</span></p>
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<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(0, 0, 10) !important;font-size:11pt;font-family:Arial;line-height:normal">Grzegorz Chojnowski (EMBL) : ARP/wARP, findMySequence, checkMySequence</span></p>
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<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal">Judit Debreczeni (Astrazeneca),
</span><span style="color:rgb(0, 0, 10) !important;font-size:11pt;font-family:Arial;line-height:normal">Lucrezia</span><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal"> Catapano (MRC-LMB Cambridge) : Coot</span></p>
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<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(0, 0, 10) !important;font-size:11pt;font-family:Arial;line-height:normal">Keitaro Yamashita, Rangana Warshamanage, Rob Nicholls</span><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal"> (MRC-LMB
Cambridge) : REFMAC, Servalcat, EMDA</span></p>
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<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal">Maya Topf,
</span><span style="color:rgb(0, 0, 10) !important;font-size:11pt;font-family:Arial;line-height:normal">Tristan Cragnolini, Aaron Sweeney
</span><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal"> (</span><span style="color:rgb(0, 0, 10) !important;font-size:11pt;font-family:Arial;line-height:normal">CSSB Hamburg</span><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal">)
: Flex-EM, TEMPy</span></p>
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<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal">Tristan Croll (University of Cambridge) : ISOLDE</span></p>
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<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(0, 0, 10) !important;font-size:11pt;font-family:Arial;line-height:normal">Jon Agirre (University of York)</span><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal"> :
Privateer</span></p>
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<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(0, 0, 10) !important;font-size:11pt;font-family:Arial;line-height:normal">Jane Richardson (GCB Duke</span><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal">)
: Model validation, Molprobity</span></p>
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<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(0, 0, 10) !important;font-size:11pt;font-family:Arial;line-height:normal">Jack Turner (EBI) : EMDB</span></p>
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<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(0, 0, 10) !important;font-size:11pt;font-family:Arial;line-height:normal">Mihaly Varadi (EBI)</span><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal"> :
</span><span style="color:rgb(0, 0, 10) !important;font-size:11pt;font-family:Arial;line-height:normal">AlphaFold-DB, 3D-Beacons
</span><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal"> </span></p>
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<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal">Best wishes,</span></p>
<p dir="ltr" style="margin-top:0;margin-bottom:0;line-height:1.38"><span style="color:rgb(34, 34, 34) !important;font-size:11pt;font-family:Arial;line-height:normal">CCP-EM team</span></p>
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