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<span style="font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:#201F1E;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in">Dear 3DEM community,</span><span style="font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:black"><o:p> </o:p></span></p>

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<span style="font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:#201F1E;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in"> </span><span style="font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:black"><o:p> </o:p></span></p>

<p class="MsoNormal" style="margin:0in 0in 8pt;font-size:11pt;font-family:Calibri, sans-serif;margin-bottom:.0001pt;background:white">

<span style="font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:#201F1E;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in">the <b>2022 GRC for 3DEM</b> and associated GRS are just around

 the corner: in Castelldefels, Spain, June 19-24, 2022 (GRC; and <span style="background:white">June 18-19 GRS). The GRC has a strict 200 participant limit and a</span>t this point, we are highly over-subscribed. So far, the cancellation rate has been low,

 i.e. likely only a few more applicants on the waitlist will be accepted in the next few weeks. I apologize to all applicants who will not be accepted this year, but I encourage you to apply for the 2023 GRC.</span><span style="font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:black"><o:p> </o:p></span></p>

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<span style="font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:#201F1E;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in"><br>

</span></p>

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<span style="font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:black;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in;background:white">As you know, the meeting highlights the latest

 technical and scientific developments in our field, </span><span style="font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:black;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in">and

we have an interesting program lined up: <a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__www.grc.org_three-2Ddimensional-2Delectron-2Dmicroscopy-2Dconference_2022_&d=DwMF-g&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=xErEv8h-Kf3omZDsYZgCbCp2h4jeVhqH45ImPcELi_kodUdewiJhCju1-YsQU-XR&s=-lV8BQtU_low1V-5qS9KnM6dnI3eSEalzh2s3DvCQJQ&e=" target="_blank">https://www.grc.org/three-dimensional-electron-microscopy-conference/2022/</a>.

<o:p> </o:p></span></p>

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<span style="font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:black;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in"><o:p><br>

</o:p></span></p>

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<span style="color: black; font-family: "Times New Roman", serif; font-size: 12pt;">We have also kept

<b style="font-family: "Times New Roman", serif; font-size: 12pt; font-style: inherit; font-variant-ligatures: inherit; font-variant-caps: inherit;">2 speaker slots open for late-breaking, technical topics<span style="color: black; font-family: "Times New Roman", serif; font-size: 12pt;">.

 So if you have a </span><b style="font-family: "Times New Roman", serif; font-size: 12pt; font-style: inherit; font-variant-ligatures: inherit; font-variant-caps: inherit;">technically innovative, unpublished story that you think the cryo-EM/3DEM community

 would be interested in and that you would like to present at the 2022 GRC meeting, please email me directly @ [daniela.nicastro@utsouthwestern.edu]

</b><span style="color: black; font-family: "Times New Roman", serif; font-size: 12pt;">(please

</span><b style="font-family: "Times New Roman", serif; font-size: 12pt; font-style: inherit; font-variant-ligatures: inherit; font-variant-caps: inherit;"><i><u>DO NOT</u></i></b><span style="color: black; font-family: "Times New Roman", serif; font-size: 12pt;">

“reply all” or reply to <a href="mailto:3dem@ncmir.ucsd.edu" style="font-family: "Times New Roman", serif; font-size: 12pt;">3dem@ncmir.ucsd.edu</a><span style="color: black; font-family: "Times New Roman", serif; font-size: 12pt;"> to ensure confidentiality!).

Please send me a brief email with suggested title and a few sentences about the technical advance that you would like to report. I look forward to Your suggestion.

</span><o:p style="font-family: "Times New Roman", serif; font-size: 12pt; font-style: inherit; font-variant-ligatures: inherit; font-variant-caps: inherit; font-weight: inherit;"> </o:p><br>

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<p class="MsoNormal" style="margin:0in 0in 8pt;font-size:11pt;font-family:Calibri, sans-serif;margin-bottom:.0001pt;background:white">

<span style="font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:black;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in"><o:p> </o:p></span></p>

<p class="MsoNormal" style="margin:0in 0in 8pt;font-size:11pt;font-family:Calibri, sans-serif;margin-bottom:.0001pt;background:white">

<span style="font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:black;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in">Thanks and

</span><span style="font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:#201F1E;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in">best wishes, </span></p>

<p class="MsoNormal" style="margin:0in 0in 8pt;font-size:11pt;font-family:Calibri, sans-serif;margin-bottom:.0001pt;background:white">

<span style="font-size: 12pt; font-family: "Times New Roman", serif; color: rgb(32, 31, 30); border-width: 1pt; border-style: none; border-color: windowtext; padding: 0in;">Daniela </span><span style="color: black; font-size: 12pt; font-family: "Times New Roman", serif;"><o:p> </o:p></span></p>

<p class="MsoNormal" style="margin:0in 0in 8pt;font-size:11pt;font-family:Calibri, sans-serif;margin-bottom:.0001pt">

<span style="font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:#201F1E;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in">(2022 3DEM GRC Chair)  </span><span style="font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:black"><o:p> </o:p></span></p>

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<span style="mso-ascii-font-family:Calibri;mso-fareast-font-family:"Times New Roman";mso-hansi-font-family:Calibri;mso-bidi-font-family:Calibri;color:black;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in"><br>

</span></p>

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<span style="font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:black">P.S.: for those accepted to the GRC: 1) please ensure that you have also

<b><i>registered</i></b>, and 2) poster presenters will soon be contacted with additional information. I look forward to meeting you soon in Spain.</span></p>

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<span style="font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:#201F1E;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in"><br>

</span><span style="mso-ascii-font-family:Calibri;mso-fareast-font-family:"Times New Roman";mso-hansi-font-family:Calibri;mso-bidi-font-family:Calibri;color:black;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in">-----------------------------------------------</span><span style="font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:black"><o:p> </o:p></span></p>

<p class="MsoNormal" style="margin:0in 0in 8pt;font-size:11pt;font-family:Calibri, sans-serif;margin-bottom:.0001pt">

<span style="mso-ascii-font-family:Calibri;mso-fareast-font-family:"Times New Roman";mso-hansi-font-family:Calibri;mso-bidi-font-family:Calibri;color:black;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in">Daniela Nicastro, PhD</span><span style="font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-font-family:"Times New Roman";color:black"><o:p> </o:p></span></p>

<p class="MsoNormal" style="margin:0in 0in 8pt;font-size:11pt;font-family:Calibri, sans-serif;margin-bottom:.0001pt">

<span style="mso-ascii-font-family:Calibri;mso-fareast-font-family:"Times New Roman";mso-hansi-font-family:Calibri;mso-bidi-font-family:Calibri;color:black;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in">Professor<br style="mso-special-character:line-break">

</span><span style="font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-font-family:"Times New Roman";color:black"><o:p> </o:p></span></p>

<p class="MsoNormal" style="margin:0in 0in 8pt;font-size:11pt;font-family:Calibri, sans-serif;margin-bottom:.0001pt">

<span style="mso-ascii-font-family:Calibri;mso-fareast-font-family:"Times New Roman";mso-hansi-font-family:Calibri;mso-bidi-font-family:Calibri;color:black;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in">UT Southwestern Medical

 Center</span><span style="font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-font-family:"Times New Roman";color:black"><o:p> </o:p></span></p>

<p class="MsoNormal" style="margin:0in 0in 8pt;font-size:11pt;font-family:Calibri, sans-serif;margin-bottom:.0001pt">

<span style="mso-ascii-font-family:Calibri;mso-fareast-font-family:"Times New Roman";mso-hansi-font-family:Calibri;mso-bidi-font-family:Calibri;color:black;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in">Department of Cell Biology<br>

NL Building (North Campus), Room NL5-108B</span><span style="font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-font-family:"Times New Roman";color:black"><o:p> </o:p></span></p>

<p class="MsoNormal" style="margin:0in 0in 8pt;font-size:11pt;font-family:Calibri, sans-serif;margin-bottom:.0001pt">

<span style="mso-ascii-font-family:Calibri;mso-fareast-font-family:"Times New Roman";mso-hansi-font-family:Calibri;mso-bidi-font-family:Calibri;color:black;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in">6000 Harry Hines Blvd.</span><span style="font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-font-family:"Times New Roman";color:black"><o:p> </o:p></span></p>

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<span style="mso-ascii-font-family:Calibri;mso-fareast-font-family:"Times New Roman";mso-hansi-font-family:Calibri;mso-bidi-font-family:Calibri;color:black;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in">Dallas, TX 75390-9039</span><span style="font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-font-family:"Times New Roman";color:black"><o:p> </o:p></span></p>

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<span style="mso-ascii-font-family:Calibri;mso-fareast-font-family:"Times New Roman";mso-hansi-font-family:Calibri;mso-bidi-font-family:Calibri;color:black;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in"> </span><span style="font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-font-family:"Times New Roman";color:black"><o:p> </o:p></span></p>

<p class="MsoNormal" style="margin:0in 0in 8pt;font-size:11pt;font-family:Calibri, sans-serif;margin-bottom:.0001pt">

<span style="mso-ascii-font-family:Calibri;mso-fareast-font-family:"Times New Roman";mso-hansi-font-family:Calibri;mso-bidi-font-family:Calibri;color:black;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in">phone: 001-214-648-3925</span><span style="font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-font-family:"Times New Roman";color:black"><o:p> </o:p></span></p>

<span style="font-size:11.0pt;font-family:"Calibri",sans-serif;mso-fareast-font-family:"Times New Roman";color:black;border:none windowtext 1.0pt;mso-border-alt:none windowtext 0in;padding:0in;mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language:AR-SA">email: Daniela.Nicastro@utsouthwestern.edu<br>

<a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__www.utsouthwestern.edu_labs_nicastro_&d=DwMF-g&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=UCG4d6wLu-eWmPlOzt_ndbkfkwKhVSFksM7Oq4UjvvSga3PjmK2n-7gxVFoqTgk0&s=9TteF1K4g0e3DPKGukdFElDtkJcOjF5n04F5oWKQMDI&e=" id="LPNoLPOWALinkPreview">https://www.utsouthwestern.edu/labs/nicastro/</a></span><br>

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<p style="text-align:right"><span style="font-size:10pt;font-family:"Helvetica","sans-serif"; color:#666D70;">The future of medicine, today.</span></p>

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