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<p class="msipheadera14961df" style="margin:0in"><span style="font-size:12.0pt;color:#03C03C">Public</span><o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Dear all,<o:p></o:p></p>
<p class="MsoNormal">I have been noticed that the link for application was not working a couple of days ago.<o:p></o:p></p>
<p class="MsoNormal">It is back again. Please, use it if you are interested in applying!<o:p></o:p></p>
<p class="MsoNormal"><span style="color:black;background:white"><a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__jobs.merck.com_us_en_job_R176608_Associate-2DPrincipal-2DScientist-2DComputational-2Dand-2DStructural-2DChemistry_&d=DwMFAg&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=2Mt_RJK7pqMOFiGjmIXPMF2H_9alKSy1KsRIcs-ymrrqWBkLvAyXCL1mdMIq69D5&s=xFjf2ea-Xu8RHmyPaJzdlK5jdOU6ojbtHKpmPuyWRkw&e=">https://jobs.merck.com/us/en/job/R176608/Associate-Principal-Scientist-Computational-and-Structural-Chemistry/</a></span><span style="background:white"><o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Description of the position is as follows:<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:6.0pt;margin-left:.5in">
<span style="font-family:"Invention-Rg",serif">We are seeking a creative, self-motivated structural biologist with exceptional interpersonal and problem-solving skills to join the Computational and Structural Chemistry (CSC) group in Kenilworth, NJ, USA. CSC
 is a diverse and inclusive team of more than 100 structural scientists, computational chemists, informaticians, mass spectrometrists, biophysicists, and protein scientists who employ state of the art capabilities to drive drug design. We are an integral arm
 of both discovery and process chemistry and collaborate seamlessly with teams around the globe to innovate and invent better molecules faster.  We are looking for an accomplished structural biologist to support drug discovery through the generation and analysis
 of Cryo-EM atomic structures of therapeutically important protein targets. The successful candidate will join our growing CSC team and be responsible for all aspects of the structural biology process, from sample preparation and data collection through data
 processing and structure determination. <o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:6.0pt;margin-left:.5in">
<span style="font-family:"Invention-Rg",serif">The successful candidate will be capable of advancing their own work and that of other scientists that they oversee in the context of drug discovery projects goals; contribute to hypotheses generation related to
 chemistry project and derived from structural information; designing experiments required to test hypotheses or recommend decisions based on a wholistic understanding of the project. To achieve those goals, the candidate will have immediate access to an internal
 Krios G3i microscope equipped with a K3 and FFI, personal assisted collection and additional access to a variety of CROs that perform Cryo-EM work for our Company on a routine basis. At the same time, the structural scientist will establish a strong network
 of internal interactions across locations but also to leverage external collaborations to keep our team at the cutting edge of evolution in the Cryo-EM and structure based drug discovery fields.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:6.0pt;margin-left:.5in">
<span style="font-family:"Invention-Rg",serif">Consistently cited as a great place to work, our Company employs talented people who discover, develop, manufacture, and market a wide range of vaccines and medicines to address unmet medical needs. Each of us
 is joined by an extraordinary sense of purpose — bringing our Company’s finest achievements to people worldwide. Our Company's Kenilworth campus is located within commuting distance from New York City.  This proximity allows for close interactions with the
 quickly expanding Cryo-EM community in all specialized fields as well as the structural biology community at large, giving easy access to the latest developments in the field.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:6.0pt;margin-left:.5in;background:white">
<b><u><span style="font-family:inherit;color:black">Required Experience and Skills:</span></u></b><span style="font-family:"Invention-Rg",serif;color:black"><o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:6.0pt;margin-left:1.0in;text-indent:-.25in;mso-list:l1 level1 lfo2;background:white">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:black"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">        
</span></span></span><![endif]><span style="font-family:"Invention-Rg",serif;color:black">PhD degree in structural biology with a minimum of two (2) years of experience in an industrial setting (pharmaceutical or biotech company)<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:6.0pt;margin-left:1.0in;text-indent:-.25in;mso-list:l1 level1 lfo2;background:white">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:black"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">        
</span></span></span><![endif]><span style="font-family:"Invention-Rg",serif;color:black">M.S. or B.S. in chemistry, biochemistry, biophysics or a related field with a minimum of seven (7) or a minimum of ten (10) years of experience in an industrial setting
 respectively.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:6.0pt;margin-left:1.0in;text-indent:-.25in;mso-list:l1 level1 lfo2;background:white">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:black"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">        
</span></span></span><![endif]><span style="font-family:"Invention-Rg",serif;color:black">Demonstrated Cryo-EM experience in sample preparation, image processing & structure determination for atomic resolution single particle Cryo-EM.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:6.0pt;margin-left:1.0in;text-indent:-.25in;mso-list:l1 level1 lfo2;background:white">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:black"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">        
</span></span></span><![endif]><span style="font-family:"Invention-Rg",serif;color:black">Excellent communication skills (written, presentation, and oral) that enhance team-based progress is required.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:6.0pt;margin-left:1.0in;text-indent:-.25in;mso-list:l1 level1 lfo2;background:white">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:black"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">        
</span></span></span><![endif]><span style="font-family:"Invention-Rg",serif;color:black">Demonstrated potential to lead projects and collaborate with scientists outside of their field of expertise.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:6.0pt;margin-left:1.0in;text-indent:-.25in;mso-list:l1 level1 lfo2;background:white">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:black"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">        
</span></span></span><![endif]><span style="font-family:"Invention-Rg",serif;color:black">Ability to drive external scientific interactions by publishing in peer-reviewed journals, presenting in external scientific meetings and/or establishing external collaborations.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:6.0pt;margin-left:1.0in;text-indent:-.25in;mso-list:l1 level1 lfo2;background:white">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:black"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">        
</span></span></span><![endif]><span style="font-family:"Invention-Rg",serif;color:black">Demonstrated potential to manage and mentor other scientists in structural biology.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:6.0pt;margin-left:1.0in;text-indent:-.25in;mso-list:l1 level1 lfo2;background:white">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:black"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">        
</span></span></span><![endif]><span style="font-family:"Invention-Rg",serif;color:black">Ability to work effectively and flexibly within timelines.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:6.0pt;margin-left:.5in;background:white">
<b><u><span style="font-family:inherit;color:black">Preferred Experience and Skills:</span></u></b><span style="font-family:"Invention-Rg",serif;color:black"><o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:6.0pt;margin-left:1.0in;text-indent:-.25in;mso-list:l0 level1 lfo4;background:white">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:black"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">        
</span></span></span><![endif]><span style="font-family:"Invention-Rg",serif;color:black">Experience with structure determination of antigen:antibody complexes.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:6.0pt;margin-left:1.0in;text-indent:-.25in;mso-list:l0 level1 lfo4;background:white">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:black"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">        
</span></span></span><![endif]><span style="font-family:"Invention-Rg",serif;color:black">Experience with structure determination of small molecule protein complexes.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:6.0pt;margin-left:1.0in;text-indent:-.25in;mso-list:l0 level1 lfo4;background:white">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:black"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">        
</span></span></span><![endif]><span style="font-family:"Invention-Rg",serif;color:black">Experience with the application of hybrid structural techniques to answer biological questions.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:6.0pt;margin-left:1.0in;text-indent:-.25in;mso-list:l0 level1 lfo4;background:white">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:black"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">        
</span></span></span><![endif]><span style="font-family:"Invention-Rg",serif;color:black">Ability to manage multiple projects and subsequent prioritization.<o:p></o:p></span></p>
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</span></span></span><![endif]><span style="font-family:"Invention-Rg",serif;color:black">Experience with CryoSPARC live data processing software.<o:p></o:p></span></p>
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</span></span></span><![endif]><span style="font-family:"Invention-Rg",serif;color:black">Experience with biophysical and functional characterization methods (e.g.  SPR, NMR, thermal shift and calorimetric assays) to guide construct design and optimization
 of solution conditions for successful structural outcomes.<o:p></o:p></span></p>
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</span></span></span><![endif]><span style="font-family:"Invention-Rg",serif;color:black">Experience using computational tools for protein engineering and design.<o:p></o:p></span></p>
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<p class="MsoNormal"><b>From:</b> Collaborative Computational Project in Electron cryo-Microscopy <CCPEM@JISCMAIL.AC.UK>
<b>On Behalf Of </b>Gomez Llorente, Yacob<br>
<b>Sent:</b> Monday, April 25, 2022 8:01 AM<br>
<b>To:</b> CCPEM@JISCMAIL.AC.UK<br>
<b>Subject:</b> [ccpem] Open position at Merck (NJ, USA) for a cryoEM/X-ray Structural Biologist<o:p></o:p></p>
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<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><strong><span style="font-family:"Calibri",sans-serif;color:red">EXTERNAL EMAIL</span></strong> – Use caution with any links or file attachments.<o:p></o:p></p>
<p class="msipheadera14961df" style="margin:0in"><span style="font-size:12.0pt;color:#03C03C">Public</span><o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Dear all, we keep hiring at Merck!<o:p></o:p></p>
<p class="MsoNormal"><span style="color:black;background:white">Continuing with the impressive success of cryoEM at Merck we are hiring for our group in Kenilworth, looking for an structural biologist with cryoEM/Xray background and industry experience.</span><span style="background:white"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="color:black;background:white">The successful applicant will belong to the cryoEM unit at Kenilworth, NJ, and will have access to an internal Krios equipped with a K3 and FFI, personal assisted collections, a cryoEM dedicated
 GPU cluster and abundant external resources.</span><span style="background:white"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="color:black;background:white">Foreign applicants are welcomed!</span><span style="background:white"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="background:white"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="color:black;background:white">Apply at:</span><span style="background:white"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="color:black;background:white"><a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__jobs.merck.com_us_en_job_R176608_Associate-2DPrincipal-2DScientist-2DComputational-2Dand-2DStructural-2DChemistry_&d=DwMFAg&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=2Mt_RJK7pqMOFiGjmIXPMF2H_9alKSy1KsRIcs-ymrrqWBkLvAyXCL1mdMIq69D5&s=xFjf2ea-Xu8RHmyPaJzdlK5jdOU6ojbtHKpmPuyWRkw&e=">https://jobs.merck.com/us/en/job/R176608/Associate-Principal-Scientist-Computational-and-Structural-Chemistry/</a></span><span style="background:white"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="background:white"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="color:black;background:white">Please, feel free to reach out for any question at
<a href="mailto:yacob.gomez.llorente@merck.com">yacob.gomez.llorente@merck.com</a> or by LinkedIn:
<a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__www.linkedin.com_in_yacob-2Dgomez-2Dllorente-2D4b249376_&d=DwMFAg&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=2Mt_RJK7pqMOFiGjmIXPMF2H_9alKSy1KsRIcs-ymrrqWBkLvAyXCL1mdMIq69D5&s=Wh5yjeKiMPcIgJiWaRQVSe4RyrIOVUemm3jDS-4ZqJE&e=">https://www.linkedin.com/in/yacob-gomez-llorente-4b249376/</a></span><span style="background:white"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="background:white"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="color:black;background:white">Best,</span><span style="background:white"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="color:black;background:white">Yacob</span><span style="background:white"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="background:white"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="background:white"><o:p> </o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
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