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Dear All<br class="">
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Please find the details below for a postdoctoral position in the Weiss/Takagi labs:<br class="">
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All the best<br class="">
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Yuro
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<div class="">Yuichiro H. Takagi, Ph.D.<br class="">
Associate Professor<br class="">
Scientific director of cryo-EM <br class="">
Department of Biochemistry and Molecular Biology<br class="">
Indiana University School of Medicine<br class="">
<a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__twitter.com_LabTakagi&d=DwMGaQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=hBRPoO1blQ3NPLqIdOx9fCbAGX51amZddy3_y11849-2mJhlFvWsr1MSj8jI-8Qg&s=2ft6UZwh1vjC2EjvPkJTKECxURMiC_HuCq8JdtP7tXs&e=" class="">https://twitter.com/LabTakagi</a></div>
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<b class="">Postdoctoral opportunity for structure studies of the insulin analogues - insulin receptor complex by cryo-EM at Indiana University School of Medicine, Indianapolis, IN USA</b><br class="">
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We invite applications for a post-doctoral position, funded by the NIH and Helmsley Charitable Trust, focusing on cryo-EM studies of how insulin analogs bind to the insulin receptor at the laboratory of Dr. Michael A. Weiss at Department of Biochemistry & Molecular
Biology, Indiana University School of Medicine (IUSM). This project is in collaboration with the lab of Dr. Yuichiro Takagi at IUSM. Analogs include ultra-stable and glucose-responsive insulin variants of clinical interest – please see our latest publication
in this subject: <a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__www.pnas.org_doi_10.1073_pnas.2103518118&d=DwMGaQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=hBRPoO1blQ3NPLqIdOx9fCbAGX51amZddy3_y11849-2mJhlFvWsr1MSj8jI-8Qg&s=pGdtNwOH20H0zoHXAYzH7fpat5nDP6vZo80W5thWgzU&e=" class="">https://www.pnas.org/doi/10.1073/pnas.2103518118</a></div>
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The Indiana University School of Medicine (IUSM) has an EM Core with 200 kV Glacios cryo-EM with Falcon 4 camera and shared access to a 300 kV Titan Krios G4 with K3 camera, located at Purdue University as part of a regional consortium. The post-doctoral fellow
will be part of a multidisciplinary team including synthetic peptide chemists and cell biologists engaged in insulin research with translational application to the improved treatment of diabetes mellitus. A PhD in structural biology or computation protein
chemistry is required. Prior experience with cryo-EM is preferred but not required. <b class="">We will provide an extensive in-house cryo-EM training.</b> IUSM provides a diverse international community and welcomes applications from scientists of diverse
backgrounds, cultures, nationalities and genders. Non-US Citizens will require an appropriate Visa for employment in the United State.<br class="">
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If interested, please submit Curriculum Vitae (CV), letter of introduction and names of three referees (including prior or current laboratory mentors) via the link below:<br class="">
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<a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__indiana.peopleadmin.com_postings_12738&d=DwMGaQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=hBRPoO1blQ3NPLqIdOx9fCbAGX51amZddy3_y11849-2mJhlFvWsr1MSj8jI-8Qg&s=4f4cs9PRM_ooscnP3p7vR4XNupSs-dSpUYOlkCoML_o&e=" class="">https://indiana.peopleadmin.com/postings/12738</a></div>
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If you have any question, please contact Drs. Yuichiro Takagi and Michael A. Weiss, Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202 (email addresses <a href="mailto:ytakagi@iu.edu" class="">ytakagi@iu.edu</a> and <a href="mailto:weissma@iu.edu" class="">weissma@iu.edu</a>)</div>
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Yuichiro H. Takagi, Ph.D.<br class="">
Associate Professor<br class="">
Scientific director of cryo-EM <br class="">
Department of Biochemistry and Molecular Biology<br class="">
Indiana University School of Medicine<br class="">
635 Barnhill Drive, Medical Science Building 4003<br class="">
Indianapolis, IN 46202<br class="">
Office: (317) 274-2719<br class="">
Lab: (317) 274-0889<br class="">
<a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__twitter.com_LabTakagi&d=DwMGaQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=hBRPoO1blQ3NPLqIdOx9fCbAGX51amZddy3_y11849-2mJhlFvWsr1MSj8jI-8Qg&s=2ft6UZwh1vjC2EjvPkJTKECxURMiC_HuCq8JdtP7tXs&e=" class="">https://twitter.com/LabTakagi</a></div>
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