<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40">
<head>
<meta http-equiv="Content-Type" content="text/html; charset=iso-8859-7">
<meta name="ProgId" content="Word.Document">
<meta name="Generator" content="Microsoft Word 15">
<meta name="Originator" content="Microsoft Word 15">
<link rel="File-List" href="cid:filelist.xml@01D84DB5.AF3A9120"><!--[if gte mso 9]><xml>
<o:OfficeDocumentSettings>
<o:AllowPNG/>
<o:DoNotRelyOnCSS/>
</o:OfficeDocumentSettings>
</xml><![endif]--><!--[if gte mso 9]><xml>
<w:WordDocument>
<w:TrackMoves/>
<w:TrackFormatting/>
<w:EnvelopeVis/>
<w:PunctuationKerning/>
<w:ValidateAgainstSchemas/>
<w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid>
<w:IgnoreMixedContent>false</w:IgnoreMixedContent>
<w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText>
<w:DoNotPromoteQF/>
<w:LidThemeOther>EN-GB</w:LidThemeOther>
<w:LidThemeAsian>X-NONE</w:LidThemeAsian>
<w:LidThemeComplexScript>X-NONE</w:LidThemeComplexScript>
<w:Compatibility>
<w:BreakWrappedTables/>
<w:SnapToGridInCell/>
<w:WrapTextWithPunct/>
<w:UseAsianBreakRules/>
<w:DontGrowAutofit/>
<w:SplitPgBreakAndParaMark/>
<w:EnableOpenTypeKerning/>
<w:DontFlipMirrorIndents/>
<w:OverrideTableStyleHps/>
</w:Compatibility>
<m:mathPr>
<m:mathFont m:val="Cambria Math"/>
<m:brkBin m:val="before"/>
<m:brkBinSub m:val="--"/>
<m:smallFrac m:val="off"/>
<m:dispDef/>
<m:lMargin m:val="0"/>
<m:rMargin m:val="0"/>
<m:defJc m:val="centerGroup"/>
<m:wrapIndent m:val="1440"/>
<m:intLim m:val="subSup"/>
<m:naryLim m:val="undOvr"/>
</m:mathPr></w:WordDocument>
</xml><![endif]--><!--[if gte mso 9]><xml>
<w:LatentStyles DefLockedState="false" DefUnhideWhenUsed="false" DefSemiHidden="false" DefQFormat="false" DefPriority="99" LatentStyleCount="375">
<w:LsdException Locked="false" Priority="0" QFormat="true" Name="Normal"/>
<w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 1"/>
<w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 2"/>
<w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 3"/>
<w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 4"/>
<w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 5"/>
<w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 6"/>
<w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 7"/>
<w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 8"/>
<w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 9"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 1"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 2"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 3"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 4"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 5"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 6"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 7"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 8"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 9"/>
<w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 1"/>
<w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 2"/>
<w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 3"/>
<w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 4"/>
<w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 5"/>
<w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 6"/>
<w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 7"/>
<w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 8"/>
<w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 9"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Normal Indent"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="footnote text"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="annotation text"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="header"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="footer"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index heading"/>
<w:LsdException Locked="false" Priority="35" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="caption"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="table of figures"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="envelope address"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="envelope return"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="footnote reference"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="annotation reference"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="line number"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="page number"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="endnote reference"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="endnote text"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="table of authorities"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="macro"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="toa heading"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Bullet"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Number"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List 2"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List 3"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List 4"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List 5"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Bullet 2"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Bullet 3"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Bullet 4"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Bullet 5"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Number 2"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Number 3"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Number 4"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Number 5"/>
<w:LsdException Locked="false" Priority="10" QFormat="true" Name="Title"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Closing"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Signature"/>
<w:LsdException Locked="false" Priority="1" SemiHidden="true" UnhideWhenUsed="true" Name="Default Paragraph Font"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text Indent"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Continue"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Continue 2"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Continue 3"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Continue 4"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Continue 5"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Message Header"/>
<w:LsdException Locked="false" Priority="11" QFormat="true" Name="Subtitle"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Salutation"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Date"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text First Indent"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text First Indent 2"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Note Heading"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text 2"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text 3"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text Indent 2"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text Indent 3"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Block Text"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Hyperlink"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="FollowedHyperlink"/>
<w:LsdException Locked="false" Priority="22" QFormat="true" Name="Strong"/>
<w:LsdException Locked="false" Priority="20" QFormat="true" Name="Emphasis"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Document Map"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Plain Text"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="E-mail Signature"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Top of Form"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Bottom of Form"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Normal (Web)"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Acronym"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Address"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Cite"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Code"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Definition"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Keyboard"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Preformatted"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Sample"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Typewriter"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Variable"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Normal Table"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="annotation subject"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="No List"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Outline List 1"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Outline List 2"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Outline List 3"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Simple 1"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Simple 2"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Simple 3"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Classic 1"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Classic 2"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Classic 3"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Classic 4"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Colorful 1"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Colorful 2"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Colorful 3"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Columns 1"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Columns 2"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Columns 3"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Columns 4"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Columns 5"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 1"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 2"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 3"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 4"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 5"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 6"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 7"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 8"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 1"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 2"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 3"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 4"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 5"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 6"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 7"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 8"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table 3D effects 1"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table 3D effects 2"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table 3D effects 3"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Contemporary"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Elegant"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Professional"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Subtle 1"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Subtle 2"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Web 1"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Web 2"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Web 3"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Balloon Text"/>
<w:LsdException Locked="false" Priority="39" Name="Table Grid"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Theme"/>
<w:LsdException Locked="false" SemiHidden="true" Name="Placeholder Text"/>
<w:LsdException Locked="false" Priority="1" QFormat="true" Name="No Spacing"/>
<w:LsdException Locked="false" Priority="60" Name="Light Shading"/>
<w:LsdException Locked="false" Priority="61" Name="Light List"/>
<w:LsdException Locked="false" Priority="62" Name="Light Grid"/>
<w:LsdException Locked="false" Priority="63" Name="Medium Shading 1"/>
<w:LsdException Locked="false" Priority="64" Name="Medium Shading 2"/>
<w:LsdException Locked="false" Priority="65" Name="Medium List 1"/>
<w:LsdException Locked="false" Priority="66" Name="Medium List 2"/>
<w:LsdException Locked="false" Priority="67" Name="Medium Grid 1"/>
<w:LsdException Locked="false" Priority="68" Name="Medium Grid 2"/>
<w:LsdException Locked="false" Priority="69" Name="Medium Grid 3"/>
<w:LsdException Locked="false" Priority="70" Name="Dark List"/>
<w:LsdException Locked="false" Priority="71" Name="Colorful Shading"/>
<w:LsdException Locked="false" Priority="72" Name="Colorful List"/>
<w:LsdException Locked="false" Priority="73" Name="Colorful Grid"/>
<w:LsdException Locked="false" Priority="60" Name="Light Shading Accent 1"/>
<w:LsdException Locked="false" Priority="61" Name="Light List Accent 1"/>
<w:LsdException Locked="false" Priority="62" Name="Light Grid Accent 1"/>
<w:LsdException Locked="false" Priority="63" Name="Medium Shading 1 Accent 1"/>
<w:LsdException Locked="false" Priority="64" Name="Medium Shading 2 Accent 1"/>
<w:LsdException Locked="false" Priority="65" Name="Medium List 1 Accent 1"/>
<w:LsdException Locked="false" SemiHidden="true" Name="Revision"/>
<w:LsdException Locked="false" Priority="34" QFormat="true" Name="List Paragraph"/>
<w:LsdException Locked="false" Priority="29" QFormat="true" Name="Quote"/>
<w:LsdException Locked="false" Priority="30" QFormat="true" Name="Intense Quote"/>
<w:LsdException Locked="false" Priority="66" Name="Medium List 2 Accent 1"/>
<w:LsdException Locked="false" Priority="67" Name="Medium Grid 1 Accent 1"/>
<w:LsdException Locked="false" Priority="68" Name="Medium Grid 2 Accent 1"/>
<w:LsdException Locked="false" Priority="69" Name="Medium Grid 3 Accent 1"/>
<w:LsdException Locked="false" Priority="70" Name="Dark List Accent 1"/>
<w:LsdException Locked="false" Priority="71" Name="Colorful Shading Accent 1"/>
<w:LsdException Locked="false" Priority="72" Name="Colorful List Accent 1"/>
<w:LsdException Locked="false" Priority="73" Name="Colorful Grid Accent 1"/>
<w:LsdException Locked="false" Priority="60" Name="Light Shading Accent 2"/>
<w:LsdException Locked="false" Priority="61" Name="Light List Accent 2"/>
<w:LsdException Locked="false" Priority="62" Name="Light Grid Accent 2"/>
<w:LsdException Locked="false" Priority="63" Name="Medium Shading 1 Accent 2"/>
<w:LsdException Locked="false" Priority="64" Name="Medium Shading 2 Accent 2"/>
<w:LsdException Locked="false" Priority="65" Name="Medium List 1 Accent 2"/>
<w:LsdException Locked="false" Priority="66" Name="Medium List 2 Accent 2"/>
<w:LsdException Locked="false" Priority="67" Name="Medium Grid 1 Accent 2"/>
<w:LsdException Locked="false" Priority="68" Name="Medium Grid 2 Accent 2"/>
<w:LsdException Locked="false" Priority="69" Name="Medium Grid 3 Accent 2"/>
<w:LsdException Locked="false" Priority="70" Name="Dark List Accent 2"/>
<w:LsdException Locked="false" Priority="71" Name="Colorful Shading Accent 2"/>
<w:LsdException Locked="false" Priority="72" Name="Colorful List Accent 2"/>
<w:LsdException Locked="false" Priority="73" Name="Colorful Grid Accent 2"/>
<w:LsdException Locked="false" Priority="60" Name="Light Shading Accent 3"/>
<w:LsdException Locked="false" Priority="61" Name="Light List Accent 3"/>
<w:LsdException Locked="false" Priority="62" Name="Light Grid Accent 3"/>
<w:LsdException Locked="false" Priority="63" Name="Medium Shading 1 Accent 3"/>
<w:LsdException Locked="false" Priority="64" Name="Medium Shading 2 Accent 3"/>
<w:LsdException Locked="false" Priority="65" Name="Medium List 1 Accent 3"/>
<w:LsdException Locked="false" Priority="66" Name="Medium List 2 Accent 3"/>
<w:LsdException Locked="false" Priority="67" Name="Medium Grid 1 Accent 3"/>
<w:LsdException Locked="false" Priority="68" Name="Medium Grid 2 Accent 3"/>
<w:LsdException Locked="false" Priority="69" Name="Medium Grid 3 Accent 3"/>
<w:LsdException Locked="false" Priority="70" Name="Dark List Accent 3"/>
<w:LsdException Locked="false" Priority="71" Name="Colorful Shading Accent 3"/>
<w:LsdException Locked="false" Priority="72" Name="Colorful List Accent 3"/>
<w:LsdException Locked="false" Priority="73" Name="Colorful Grid Accent 3"/>
<w:LsdException Locked="false" Priority="60" Name="Light Shading Accent 4"/>
<w:LsdException Locked="false" Priority="61" Name="Light List Accent 4"/>
<w:LsdException Locked="false" Priority="62" Name="Light Grid Accent 4"/>
<w:LsdException Locked="false" Priority="63" Name="Medium Shading 1 Accent 4"/>
<w:LsdException Locked="false" Priority="64" Name="Medium Shading 2 Accent 4"/>
<w:LsdException Locked="false" Priority="65" Name="Medium List 1 Accent 4"/>
<w:LsdException Locked="false" Priority="66" Name="Medium List 2 Accent 4"/>
<w:LsdException Locked="false" Priority="67" Name="Medium Grid 1 Accent 4"/>
<w:LsdException Locked="false" Priority="68" Name="Medium Grid 2 Accent 4"/>
<w:LsdException Locked="false" Priority="69" Name="Medium Grid 3 Accent 4"/>
<w:LsdException Locked="false" Priority="70" Name="Dark List Accent 4"/>
<w:LsdException Locked="false" Priority="71" Name="Colorful Shading Accent 4"/>
<w:LsdException Locked="false" Priority="72" Name="Colorful List Accent 4"/>
<w:LsdException Locked="false" Priority="73" Name="Colorful Grid Accent 4"/>
<w:LsdException Locked="false" Priority="60" Name="Light Shading Accent 5"/>
<w:LsdException Locked="false" Priority="61" Name="Light List Accent 5"/>
<w:LsdException Locked="false" Priority="62" Name="Light Grid Accent 5"/>
<w:LsdException Locked="false" Priority="63" Name="Medium Shading 1 Accent 5"/>
<w:LsdException Locked="false" Priority="64" Name="Medium Shading 2 Accent 5"/>
<w:LsdException Locked="false" Priority="65" Name="Medium List 1 Accent 5"/>
<w:LsdException Locked="false" Priority="66" Name="Medium List 2 Accent 5"/>
<w:LsdException Locked="false" Priority="67" Name="Medium Grid 1 Accent 5"/>
<w:LsdException Locked="false" Priority="68" Name="Medium Grid 2 Accent 5"/>
<w:LsdException Locked="false" Priority="69" Name="Medium Grid 3 Accent 5"/>
<w:LsdException Locked="false" Priority="70" Name="Dark List Accent 5"/>
<w:LsdException Locked="false" Priority="71" Name="Colorful Shading Accent 5"/>
<w:LsdException Locked="false" Priority="72" Name="Colorful List Accent 5"/>
<w:LsdException Locked="false" Priority="73" Name="Colorful Grid Accent 5"/>
<w:LsdException Locked="false" Priority="60" Name="Light Shading Accent 6"/>
<w:LsdException Locked="false" Priority="61" Name="Light List Accent 6"/>
<w:LsdException Locked="false" Priority="62" Name="Light Grid Accent 6"/>
<w:LsdException Locked="false" Priority="63" Name="Medium Shading 1 Accent 6"/>
<w:LsdException Locked="false" Priority="64" Name="Medium Shading 2 Accent 6"/>
<w:LsdException Locked="false" Priority="65" Name="Medium List 1 Accent 6"/>
<w:LsdException Locked="false" Priority="66" Name="Medium List 2 Accent 6"/>
<w:LsdException Locked="false" Priority="67" Name="Medium Grid 1 Accent 6"/>
<w:LsdException Locked="false" Priority="68" Name="Medium Grid 2 Accent 6"/>
<w:LsdException Locked="false" Priority="69" Name="Medium Grid 3 Accent 6"/>
<w:LsdException Locked="false" Priority="70" Name="Dark List Accent 6"/>
<w:LsdException Locked="false" Priority="71" Name="Colorful Shading Accent 6"/>
<w:LsdException Locked="false" Priority="72" Name="Colorful List Accent 6"/>
<w:LsdException Locked="false" Priority="73" Name="Colorful Grid Accent 6"/>
<w:LsdException Locked="false" Priority="19" QFormat="true" Name="Subtle Emphasis"/>
<w:LsdException Locked="false" Priority="21" QFormat="true" Name="Intense Emphasis"/>
<w:LsdException Locked="false" Priority="31" QFormat="true" Name="Subtle Reference"/>
<w:LsdException Locked="false" Priority="32" QFormat="true" Name="Intense Reference"/>
<w:LsdException Locked="false" Priority="33" QFormat="true" Name="Book Title"/>
<w:LsdException Locked="false" Priority="37" SemiHidden="true" UnhideWhenUsed="true" Name="Bibliography"/>
<w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="TOC Heading"/>
<w:LsdException Locked="false" Priority="41" Name="Plain Table 1"/>
<w:LsdException Locked="false" Priority="42" Name="Plain Table 2"/>
<w:LsdException Locked="false" Priority="43" Name="Plain Table 3"/>
<w:LsdException Locked="false" Priority="44" Name="Plain Table 4"/>
<w:LsdException Locked="false" Priority="45" Name="Plain Table 5"/>
<w:LsdException Locked="false" Priority="40" Name="Grid Table Light"/>
<w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light"/>
<w:LsdException Locked="false" Priority="47" Name="Grid Table 2"/>
<w:LsdException Locked="false" Priority="48" Name="Grid Table 3"/>
<w:LsdException Locked="false" Priority="49" Name="Grid Table 4"/>
<w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark"/>
<w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful"/>
<w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful"/>
<w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light Accent 1"/>
<w:LsdException Locked="false" Priority="47" Name="Grid Table 2 Accent 1"/>
<w:LsdException Locked="false" Priority="48" Name="Grid Table 3 Accent 1"/>
<w:LsdException Locked="false" Priority="49" Name="Grid Table 4 Accent 1"/>
<w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark Accent 1"/>
<w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful Accent 1"/>
<w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful Accent 1"/>
<w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light Accent 2"/>
<w:LsdException Locked="false" Priority="47" Name="Grid Table 2 Accent 2"/>
<w:LsdException Locked="false" Priority="48" Name="Grid Table 3 Accent 2"/>
<w:LsdException Locked="false" Priority="49" Name="Grid Table 4 Accent 2"/>
<w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark Accent 2"/>
<w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful Accent 2"/>
<w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful Accent 2"/>
<w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light Accent 3"/>
<w:LsdException Locked="false" Priority="47" Name="Grid Table 2 Accent 3"/>
<w:LsdException Locked="false" Priority="48" Name="Grid Table 3 Accent 3"/>
<w:LsdException Locked="false" Priority="49" Name="Grid Table 4 Accent 3"/>
<w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark Accent 3"/>
<w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful Accent 3"/>
<w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful Accent 3"/>
<w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light Accent 4"/>
<w:LsdException Locked="false" Priority="47" Name="Grid Table 2 Accent 4"/>
<w:LsdException Locked="false" Priority="48" Name="Grid Table 3 Accent 4"/>
<w:LsdException Locked="false" Priority="49" Name="Grid Table 4 Accent 4"/>
<w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark Accent 4"/>
<w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful Accent 4"/>
<w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful Accent 4"/>
<w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light Accent 5"/>
<w:LsdException Locked="false" Priority="47" Name="Grid Table 2 Accent 5"/>
<w:LsdException Locked="false" Priority="48" Name="Grid Table 3 Accent 5"/>
<w:LsdException Locked="false" Priority="49" Name="Grid Table 4 Accent 5"/>
<w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark Accent 5"/>
<w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful Accent 5"/>
<w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful Accent 5"/>
<w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light Accent 6"/>
<w:LsdException Locked="false" Priority="47" Name="Grid Table 2 Accent 6"/>
<w:LsdException Locked="false" Priority="48" Name="Grid Table 3 Accent 6"/>
<w:LsdException Locked="false" Priority="49" Name="Grid Table 4 Accent 6"/>
<w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark Accent 6"/>
<w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful Accent 6"/>
<w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful Accent 6"/>
<w:LsdException Locked="false" Priority="46" Name="List Table 1 Light"/>
<w:LsdException Locked="false" Priority="47" Name="List Table 2"/>
<w:LsdException Locked="false" Priority="48" Name="List Table 3"/>
<w:LsdException Locked="false" Priority="49" Name="List Table 4"/>
<w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark"/>
<w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful"/>
<w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful"/>
<w:LsdException Locked="false" Priority="46" Name="List Table 1 Light Accent 1"/>
<w:LsdException Locked="false" Priority="47" Name="List Table 2 Accent 1"/>
<w:LsdException Locked="false" Priority="48" Name="List Table 3 Accent 1"/>
<w:LsdException Locked="false" Priority="49" Name="List Table 4 Accent 1"/>
<w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark Accent 1"/>
<w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful Accent 1"/>
<w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful Accent 1"/>
<w:LsdException Locked="false" Priority="46" Name="List Table 1 Light Accent 2"/>
<w:LsdException Locked="false" Priority="47" Name="List Table 2 Accent 2"/>
<w:LsdException Locked="false" Priority="48" Name="List Table 3 Accent 2"/>
<w:LsdException Locked="false" Priority="49" Name="List Table 4 Accent 2"/>
<w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark Accent 2"/>
<w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful Accent 2"/>
<w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful Accent 2"/>
<w:LsdException Locked="false" Priority="46" Name="List Table 1 Light Accent 3"/>
<w:LsdException Locked="false" Priority="47" Name="List Table 2 Accent 3"/>
<w:LsdException Locked="false" Priority="48" Name="List Table 3 Accent 3"/>
<w:LsdException Locked="false" Priority="49" Name="List Table 4 Accent 3"/>
<w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark Accent 3"/>
<w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful Accent 3"/>
<w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful Accent 3"/>
<w:LsdException Locked="false" Priority="46" Name="List Table 1 Light Accent 4"/>
<w:LsdException Locked="false" Priority="47" Name="List Table 2 Accent 4"/>
<w:LsdException Locked="false" Priority="48" Name="List Table 3 Accent 4"/>
<w:LsdException Locked="false" Priority="49" Name="List Table 4 Accent 4"/>
<w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark Accent 4"/>
<w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful Accent 4"/>
<w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful Accent 4"/>
<w:LsdException Locked="false" Priority="46" Name="List Table 1 Light Accent 5"/>
<w:LsdException Locked="false" Priority="47" Name="List Table 2 Accent 5"/>
<w:LsdException Locked="false" Priority="48" Name="List Table 3 Accent 5"/>
<w:LsdException Locked="false" Priority="49" Name="List Table 4 Accent 5"/>
<w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark Accent 5"/>
<w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful Accent 5"/>
<w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful Accent 5"/>
<w:LsdException Locked="false" Priority="46" Name="List Table 1 Light Accent 6"/>
<w:LsdException Locked="false" Priority="47" Name="List Table 2 Accent 6"/>
<w:LsdException Locked="false" Priority="48" Name="List Table 3 Accent 6"/>
<w:LsdException Locked="false" Priority="49" Name="List Table 4 Accent 6"/>
<w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark Accent 6"/>
<w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful Accent 6"/>
<w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful Accent 6"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Mention"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Smart Hyperlink"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Hashtag"/>
<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Unresolved Mention"/>
</w:LatentStyles>
</xml><![endif]--><style><!--
/* Font Definitions */
@font-face
{font-family:"Cambria Math";
panose-1:2 4 5 3 5 4 6 3 2 4;
mso-font-charset:0;
mso-generic-font-family:roman;
mso-font-pitch:variable;
mso-font-signature:-536869121 1107305727 33554432 0 415 0;}
@font-face
{font-family:Calibri;
panose-1:2 15 5 2 2 2 4 3 2 4;
mso-font-charset:0;
mso-generic-font-family:swiss;
mso-font-pitch:variable;
mso-font-signature:-469750017 -1073732485 9 0 511 0;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{mso-style-unhide:no;
mso-style-qformat:yes;
mso-style-parent:"";
margin:0cm;
margin-bottom:.0001pt;
mso-pagination:widow-orphan;
font-size:11.0pt;
font-family:"Calibri",sans-serif;
mso-fareast-font-family:Calibri;
mso-fareast-language:EN-US;}
a:link, span.MsoHyperlink
{mso-style-priority:99;
color:#0563C1;
text-decoration:underline;
text-underline:single;}
a:visited, span.MsoHyperlinkFollowed
{mso-style-noshow:yes;
mso-style-priority:99;
color:#954F72;
text-decoration:underline;
text-underline:single;}
p.MsoPlainText, li.MsoPlainText, div.MsoPlainText
{mso-style-noshow:yes;
mso-style-priority:99;
mso-style-link:"Plain Text Char";
margin:0cm;
margin-bottom:.0001pt;
mso-pagination:widow-orphan;
font-size:11.0pt;
font-family:"Calibri",sans-serif;
mso-fareast-font-family:Calibri;}
p.MsoNoSpacing, li.MsoNoSpacing, div.MsoNoSpacing
{mso-style-priority:1;
mso-style-unhide:no;
mso-style-qformat:yes;
margin:0cm;
margin-bottom:.0001pt;
mso-pagination:widow-orphan;
font-size:11.0pt;
font-family:"Calibri",sans-serif;
mso-fareast-font-family:Calibri;
mso-fareast-language:EN-US;}
p.MsoListParagraph, li.MsoListParagraph, div.MsoListParagraph
{mso-style-priority:34;
mso-style-unhide:no;
mso-style-qformat:yes;
margin-top:0cm;
margin-right:0cm;
margin-bottom:0cm;
margin-left:36.0pt;
margin-bottom:.0001pt;
mso-pagination:widow-orphan;
font-size:11.0pt;
font-family:"Calibri",sans-serif;
mso-fareast-font-family:Calibri;
mso-fareast-language:EN-US;}
span.EmailStyle18
{mso-style-type:personal-compose;
mso-style-noshow:yes;
mso-style-unhide:no;
mso-ansi-font-size:11.0pt;
mso-bidi-font-size:11.0pt;
font-family:"Calibri",sans-serif;
mso-ascii-font-family:Calibri;
mso-hansi-font-family:Calibri;
mso-bidi-font-family:Calibri;
color:windowtext;
font-weight:normal;
font-style:normal;
text-decoration:none;
text-underline:none;
text-decoration:none;
text-line-through:none;}
span.PlainTextChar
{mso-style-name:"Plain Text Char";
mso-style-noshow:yes;
mso-style-priority:99;
mso-style-unhide:no;
mso-style-locked:yes;
mso-style-link:"Plain Text";
mso-ansi-font-size:11.0pt;
mso-bidi-font-size:11.0pt;
font-family:"Calibri",sans-serif;
mso-ascii-font-family:Calibri;
mso-hansi-font-family:Calibri;
mso-bidi-font-family:Calibri;
mso-fareast-language:EN-GB;}
span.apple-converted-space
{mso-style-name:apple-converted-space;
mso-style-unhide:no;}
.MsoChpDefault
{mso-style-type:export-only;
mso-default-props:yes;
font-size:10.0pt;
mso-ansi-font-size:10.0pt;
mso-bidi-font-size:10.0pt;
mso-fareast-font-family:Calibri;
mso-fareast-language:EN-US;}
@page WordSection1
{size:612.0pt 792.0pt;
margin:72.0pt 72.0pt 72.0pt 72.0pt;
mso-header-margin:36.0pt;
mso-footer-margin:36.0pt;
mso-paper-source:0;}
div.WordSection1
{page:WordSection1;}
--></style><!--[if gte mso 10]><style>/* Style Definitions */
table.MsoNormalTable
{mso-style-name:"Table Normal";
mso-tstyle-rowband-size:0;
mso-tstyle-colband-size:0;
mso-style-noshow:yes;
mso-style-priority:99;
mso-style-parent:"";
mso-padding-alt:0cm 5.4pt 0cm 5.4pt;
mso-para-margin:0cm;
mso-para-margin-bottom:.0001pt;
mso-pagination:widow-orphan;
font-size:10.0pt;
font-family:"Times New Roman",serif;
mso-fareast-language:EN-US;}
</style><![endif]--><!--[if gte mso 9]><xml>
<o:shapedefaults v:ext="edit" spidmax="1026" />
</xml><![endif]--><!--[if gte mso 9]><xml>
<o:shapelayout v:ext="edit">
<o:idmap v:ext="edit" data="1" />
</o:shapelayout></xml><![endif]-->
</head>
<body lang="EN-GB" link="#0563C1" vlink="#954F72" style="tab-interval:36.0pt">
<div class="WordSection1">
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-bidi-font-family:Calibri"><o:p> </o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-bidi-font-family:Calibri">Dear all,</span></font><span style="mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:Calibri"><o:p></o:p></span></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-bidi-font-family:Calibri"><o:p> </o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-bidi-font-family:Calibri">this is to inform interested users from academics and industry that the Centre for Integrative Biology (CBI) / IGBMC at Illkirch/Strassburg, France
is happy to offer - as part of the iNEXT-Discovery infrastructure - 3 types of access modalities:<o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-bidi-font-family:Calibri"><o:p> </o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-fareast-font-family:Calibri;mso-bidi-font-family:Calibri;mso-fareast-language:EN-GB;mso-no-proof:yes">- high-resolution single particle cryo-EM<o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-fareast-font-family:Calibri;mso-bidi-font-family:Calibri;mso-fareast-language:EN-GB;mso-no-proof:yes">- enhenced support for cryo-EM (“from sample to classes”: which includes
negative staining, cryo-EM tests & sample optimization tests on characterized protein samples, grid screening, early/mid stage cryo-EM data collection)<o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-fareast-font-family:Calibri;mso-bidi-font-family:Calibri;mso-fareast-language:EN-GB;mso-no-proof:yes">- cryo electron tomography<o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-fareast-font-family:Calibri;mso-bidi-font-family:Calibri;mso-fareast-language:EN-GB;mso-no-proof:yes"><o:p> </o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-fareast-font-family:Calibri;mso-bidi-font-family:Calibri;mso-fareast-language:EN-GB;mso-no-proof:yes"><a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__inext-2Ddiscovery.eu_submit-2Dproposal&d=DwMFCQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=TSHrovwmas0Sfg5d1sgK3xgJT8ORaZyS70uJy1kuPRhCvRhTdch-tX0O-obZ4JsX&s=7eIZ0YjIWkLlPC5CNnyAMupXHUZt1JcHajtOMAQyxlY&e=">https://inext-discovery.eu/submit-proposal</a><o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-fareast-font-family:Calibri;mso-bidi-font-family:Calibri;mso-fareast-language:EN-GB;mso-no-proof:yes"><o:p> </o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-fareast-font-family:Calibri;mso-bidi-font-family:Calibri;mso-fareast-language:EN-GB;mso-no-proof:yes">Best regards,<o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-fareast-font-family:Calibri;mso-bidi-font-family:Calibri;mso-fareast-language:EN-GB;mso-no-proof:yes"><o:p> </o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-fareast-font-family:Calibri;mso-bidi-font-family:Calibri;mso-fareast-language:EN-GB;mso-no-proof:yes">Bruno Klaholz<o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-fareast-font-family:Calibri;mso-bidi-font-family:Calibri;mso-fareast-language:EN-GB;mso-no-proof:yes"><o:p> </o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span lang="EN-US" style="font-size:11.0pt;mso-bidi-font-family:Calibri;mso-ansi-language:EN-US"><o:p> </o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span lang="EN-US" style="font-size:11.0pt;mso-bidi-font-family:Calibri;mso-ansi-language:EN-US"><o:p> </o:p></span></font></p>
<p class="MsoNormal" style="background:white"><u><font size="2" color="#212121" face="Calibri"><span lang="EN-US" style="font-size:11.0pt;mso-bidi-font-family:Calibri;color:#212121;mso-ansi-language:EN-US">Cryo-EM facilities at CBI/IGBMC:</span></font></u><font color="#212121"><span lang="EN-US" style="mso-bidi-font-family:Calibri;color:#212121;mso-ansi-language:EN-US"><o:p></o:p></span></font></p>
<p class="MsoNormal" style="background:white"><font size="2" color="#212121" face="Calibri"><span lang="EN-US" style="font-size:11.0pt;mso-bidi-font-family:Calibri;color:#212121;mso-ansi-language:EN-US"><o:p> </o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span lang="EN-US" style="font-size:11.0pt;mso-bidi-font-family:Calibri;mso-ansi-language:EN-US">The cryo-EM facility has Titan Krios and Glacios cryo electron microscopes for cryo-EM and tomography, cryo-FIB/SEM,
super-resolution imaging (dSTORM), and a suite of associated equipments for sample preparation (grid freezing with Vitrobot and new Chameleon, HPF) and dedicated computing resources for image analysis, processing and 3D reconstruction by fluorescence microscopy,
single particle cryo-EM (including on-the-fly data processing) and cryo electron tomography (cryo-ET). The Titan Krios microscope is equipped with Volta phase plate (VPP) and Cs corrector, GIF energy filter and K3 & Falcon 3 cameras, the Glacios with a K2
camera and a Ceta D camera for micro electron diffraction (</span></font><span lang="EN-US" style="mso-ansi-language:EN-US">ì</span><span lang="EN-US" style="mso-bidi-font-family:Calibri;mso-ansi-language:EN-US">ED); a further 300 kV instrument is to be installed
2022/2023.<o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><font size="2" color="#212121" face="Calibri"><span lang="EN-US" style="font-size:11.0pt;mso-bidi-font-family:Calibri;color:#212121;mso-ansi-language:EN-US"><o:p> </o:p></span></font></p>
<p class="MsoNormal" style="background:white"><font size="2" color="#212121" face="Calibri"><span lang="EN-US" style="font-size:11.0pt;mso-bidi-font-family:Calibri;color:#212121;mso-ansi-language:EN-US">The Centre for Integrative Biology (CBI) at IGBMC, Illkirch/Strasbourg,
France, provides a cutting-edge scientific and technological environment in integrated structural biology to address the structure and function of biological systems, notably on gene expression, from the atomic, molecular to the tissue scales. The CBI
</span></font><span style="mso-bidi-font-family:Calibri"><a href="https://urldefense.proofpoint.com/v2/url?u=http-3A__www.igbmc.fr_grandesstructures_cbi_&d=DwMFCQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=TSHrovwmas0Sfg5d1sgK3xgJT8ORaZyS70uJy1kuPRhCvRhTdch-tX0O-obZ4JsX&s=wH6QiNF3xopUSc4W1dmwY6W34Y02oTcW3V-jZrSZ21A&e="><span lang="EN-US" style="mso-ansi-language:EN-US">http://www.igbmc.fr/grandesstructures/cbi</span></a></span><font color="#212121"><span lang="EN-US" style="mso-bidi-font-family:Calibri;color:#212121;mso-ansi-language:EN-US">
hosts the French and European Infrastructures for Integrated Structural Biology, FRISBI
</span></font><span lang="EN-US" style="mso-bidi-font-family:Calibri;mso-ansi-language:EN-US"><a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__frisbi.eu_&d=DwMFCQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=TSHrovwmas0Sfg5d1sgK3xgJT8ORaZyS70uJy1kuPRhCvRhTdch-tX0O-obZ4JsX&s=wsrVDJhtqGUNwWfIRJOawjDsjOxeCtQypni62zHbhJs&e=">https://frisbi.eu</a>,
<font color="#212121"><span style="color:#212121">Instruct</span></font>-ERIC<font color="#212121"><span style="color:#212121">
</span></font></span><span style="mso-bidi-font-family:Calibri"><a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__www.structuralbiology.eu_&d=DwMFCQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=TSHrovwmas0Sfg5d1sgK3xgJT8ORaZyS70uJy1kuPRhCvRhTdch-tX0O-obZ4JsX&s=tMzYCLoTATbsq0iA3ucJnYY0Qi2_sFyk_RMflqspheU&e="><span lang="EN-US" style="mso-ansi-language:EN-US">https://www.structuralbiology.eu</span></a></span><font color="#212121"><span lang="EN-US" style="mso-bidi-font-family:Calibri;color:#212121;mso-ansi-language:EN-US"> </span></font><span lang="EN-US" style="mso-bidi-font-family:Calibri;mso-ansi-language:EN-US">and
iNext-Discovery <a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__inext-2Ddiscovery.eu&d=DwMFCQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=TSHrovwmas0Sfg5d1sgK3xgJT8ORaZyS70uJy1kuPRhCvRhTdch-tX0O-obZ4JsX&s=bXYJMb926c-xtx0JrCY2gQIj0_cPAdiP3XndCrwk4tk&e=">https://inext-discovery.eu</a><font color="#212121"><span style="color:#212121">. Nodes of FRISBI and Instruct-ERIC also provide access for protein sample production, characterisation and structural analysis.<o:p></o:p></span></font></span></p>
<p class="MsoNormal" style="background:white"><font size="2" color="#212121" face="Calibri"><span lang="EN-US" style="font-size:11.0pt;mso-bidi-font-family:Calibri;color:#212121;mso-ansi-language:EN-US"><o:p> </o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span lang="EN-US" style="font-size:11.0pt;mso-fareast-font-family:Calibri;mso-ansi-language:EN-US;mso-fareast-language:EN-GB;mso-no-proof:yes"><o:p> </o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-fareast-font-family:Calibri;mso-fareast-language:EN-GB;mso-no-proof:yes"><o:p> </o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Times New Roman"><span style="font-size:11.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:Calibri;mso-fareast-language:EN-GB;mso-no-proof:yes">###########################################################################<o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Times New Roman"><span style="font-size:11.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:Calibri;mso-fareast-language:EN-GB;mso-no-proof:yes">Bruno P. Klaholz<o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Times New Roman"><span style="font-size:11.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:Calibri;mso-fareast-language:EN-GB;mso-no-proof:yes">Centre for Integrative Biology<o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Times New Roman"><span style="font-size:11.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:Calibri;mso-fareast-language:EN-GB;mso-no-proof:yes">Department of Integrated Structural Biology<br>
Institute of Genetics and of Molecular and Cellular Biology<br>
IGBMC - UMR 7104 - U 1258<o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Times New Roman"><span style="font-size:11.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:Calibri;mso-fareast-language:EN-GB;mso-no-proof:yes">1, rue Laurent Fries<br>
BP 10142 <br>
67404 ILLKIRCH CEDEX<br>
FRANCE<o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Times New Roman"><span style="font-size:11.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:Calibri;mso-fareast-language:EN-GB;mso-no-proof:yes">Tel. from abroad:<b><font color="red"><span style="color:red;font-weight:bold">
</span></font></b>0033.369.48.52.78<br>
Tel. inside France: 03.69.48.52.78<br>
websites:<br>
</span></font><span style="mso-ascii-font-family:Calibri;mso-fareast-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:"Times New Roman";mso-no-proof:yes"><a href="https://urldefense.proofpoint.com/v2/url?u=http-3A__www.igbmc.fr_Klaholz&d=DwMFCQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=TSHrovwmas0Sfg5d1sgK3xgJT8ORaZyS70uJy1kuPRhCvRhTdch-tX0O-obZ4JsX&s=Rumn7p75eIeLhF8kuxnl5G7aYKCxLcCKxoWZxoW9vos&e="><font color="blue" face="Times New Roman"><span style="font-family:"Times New Roman",serif;color:blue">http://www.igbmc.fr/Klaholz</span></font></a></span><font face="Times New Roman"><span style="font-family:"Times New Roman",serif;mso-fareast-font-family:Calibri;mso-fareast-language:EN-GB;mso-no-proof:yes"><o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-ascii-font-family:Calibri;mso-fareast-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:"Times New Roman";mso-no-proof:yes"><a href="https://urldefense.proofpoint.com/v2/url?u=http-3A__www.igbmc.fr_grandesstructures_cbi_&d=DwMFCQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=TSHrovwmas0Sfg5d1sgK3xgJT8ORaZyS70uJy1kuPRhCvRhTdch-tX0O-obZ4JsX&s=wH6QiNF3xopUSc4W1dmwY6W34Y02oTcW3V-jZrSZ21A&e=" target="_blank"><font color="blue" face="Times New Roman"><span style="font-family:"Times New Roman",serif;color:blue;mso-fareast-language:EN-GB">http://www.igbmc.fr/grandesstructures/cbi</span></font></a></span></font><font face="Times New Roman"><span style="font-family:"Times New Roman",serif;mso-fareast-font-family:Calibri;mso-fareast-language:EN-GB;mso-no-proof:yes"><o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-ascii-font-family:Calibri;mso-fareast-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:"Times New Roman";mso-no-proof:yes"><a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__frisbi.eu&d=DwMFCQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=TSHrovwmas0Sfg5d1sgK3xgJT8ORaZyS70uJy1kuPRhCvRhTdch-tX0O-obZ4JsX&s=_LKR_P6LstyeJsLojTzhRsF5_05XygKVewmr-YSNrYk&e="><font color="blue" face="Times New Roman"><span style="font-family:"Times New Roman",serif;color:blue;mso-fareast-language:EN-GB">https://frisbi.eu</span></font></a></span></font><font face="Times New Roman"><span style="font-family:"Times New Roman",serif;mso-fareast-font-family:Calibri;mso-no-proof:yes"><o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-ascii-font-family:Calibri;mso-fareast-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:"Times New Roman";mso-no-proof:yes"><a href="https://urldefense.proofpoint.com/v2/url?u=http-3A__instruct-2Deric.com_&d=DwMFCQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=TSHrovwmas0Sfg5d1sgK3xgJT8ORaZyS70uJy1kuPRhCvRhTdch-tX0O-obZ4JsX&s=ePQwP3ZpfujbEf3BBb9hz1v1qsmJvZkG6YpdriuEYLI&e="><font color="blue" face="Times New Roman"><span style="font-family:"Times New Roman",serif;color:blue;mso-fareast-language:EN-GB;mso-bidi-font-weight:bold">http://instruct-eric.com</span></font></a></span></font><font face="Times New Roman"><span style="font-family:"Times New Roman",serif;mso-fareast-font-family:Calibri;mso-no-proof:yes"><o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt;mso-ascii-font-family:Calibri;mso-fareast-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:"Times New Roman";mso-no-proof:yes"><a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__inext-2Ddiscovery.eu_&d=DwMFCQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=TSHrovwmas0Sfg5d1sgK3xgJT8ORaZyS70uJy1kuPRhCvRhTdch-tX0O-obZ4JsX&s=1Zg5YwDUN9e-zYvl9Rx6c_0uWNiTywB2-j40KrubksE&e="><font color="blue" face="Times New Roman"><span style="font-family:"Times New Roman",serif;color:blue">https://inext-discovery.eu</span></font></a></span></font><font face="Times New Roman"><span style="font-family:"Times New Roman",serif;mso-fareast-font-family:Calibri;mso-no-proof:yes"><o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Times New Roman"><span style="font-size:11.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:Calibri;mso-no-proof:yes"><o:p> </o:p></span></font></p>
<p class="MsoNormal"><font size="2" face="Calibri"><span style="font-size:11.0pt"><o:p> </o:p></span></font></p>
</div>
</body>
</html>