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<b><span style="">Institute for Protein Innovation </span></b></p>
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<b><span style="font-size:11.0pt; font-family:"Arial",sans-serif">Post-doctoral fellow position (Opioid receptor project) </span></b></p>
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<strong><span style="font-size:11.0pt; font-family:"Helvetica Neue"; color:#333333; border:none windowtext 1.0pt; padding:0in">Reports To</span></strong><span style="font-size:11.0pt; font-family:"Helvetica Neue""> </span></h2>
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<span style="font-size:11.0pt; font-family:"Helvetica Neue"; color:black">The Postdoc will report to Shaotong Zhu (Principal Scientist). </span></p>
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<span style="font-size:11.0pt; font-family:"Arial",sans-serif; color:black">The Institute for Protein Innovation (IPI) is a nonprofit research organization advancing protein science to accelerate research and improve human health. Located on the Harvard Medical
School campus in the Boston Longwood Medical Area, IPI is pioneering a new way of doing science that uniquely combines the freedom of academia with the high-throughput scaling of industry to take on transformative projects. IPI has built a robust platform
and a repository of synthetic antibodies and other protein tools to share with the biomedical community through licensing and collaboration. The Institute’s deep protein expertise, collaborative spirit and fit-for-purpose antibodies are powering new biomedical
and therapeutic discoveries for academic and industrial researchers worldwide. </span></p>
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<b><span style="font-size:11.0pt; font-family:"Arial",sans-serif; color:black">Postdoctoral Fellow Position </span></b></p>
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<span style="font-size:11.0pt; font-family:"Arial",sans-serif; color:black">We are recruiting a talented and highly motivated postdoctoral fellow who has a keen interest in the area of antibody discovery and G protein coupled receptors. The position is available
through a very exciting and highly collaborative project involving three labs at IPI (Boston), Zuse Institute Berlin (Germany) and Freie Universität Berlin (Germany) sponsored in part by a grant from the National Science Foundation. The overall goal of this
project is to combine computational modeling and in vitro biochemical analysis to characterize the dynamics of GPCRs in both physiological and pathological conditions. The successful candidate will take advantage of the antibody production pipeline at IPI
to develop well-characterized antibodies that can distinguish structurally different conformations of GPCRs. T</span><span style="font-size:11.0pt; font-family:"Arial",sans-serif">raining will include
<span style="color:black">the high-throughput production and characterization of antigens and synthetic antibodies;
</span>membrane protein complex expression and purification; in vitro reconstitution; computational MD simulations, and related biophysical techniques.
<span style="color:black">The postdoc will conduct the experiments at IPI and is required to spend substantial time in the collaborating labs in Germany every year to receive additional training. This position has a comprehensive career development and training
opportunities in preparation for a successful independent career in both academia and industry.
</span></span><span style="font-size:11.0pt; font-family:"Arial",sans-serif; color:black; background:white">This is a 3-year fully funded program with the opportunity of extension based on performance. We offer a competitive salary including a Boston allowance
and generous benefits. </span><span style="font-size:11.0pt; font-family:"Arial",sans-serif; color:black">The target start date is Jan 1<sup>st</sup>, 2022. </span></p>
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<b><span style="font-size:11.0pt; font-family:"Arial",sans-serif; color:black">Qualifications </span></b></p>
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<li><span><span style="font-size:11.0pt; font-family:"Arial",sans-serif">A Ph.D. degree in protein biochemistry/biophysics or structural biology obtained by the time of employment.</span><span style="">
</span><span style="font-size:11.0pt; font-family:"Arial",sans-serif"> </span> </span></li><li><span style="font-size:11.0pt; font-family:"Arial",sans-serif">Experience in membrane protein expression, purification and characterization is preferred.</span><span style="">
</span><span style="font-size:11.0pt; font-family:"Arial",sans-serif"> </span></li><li><span style="font-size:11.0pt; font-family:"Arial",sans-serif; color:black">A strong publication record in peer reviewed journal publications with excellent written and oral communication skills. </span></li><li>
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<span style="font-size:11.0pt; font-family:"Arial",sans-serif; color:black"><span style="margin:0px">Ability to work in a dynamic, fast-paced, productive team environment, and willing to work collaboratively across different fields.</span><span style="margin:0px; font-family:Arial,Helvetica,sans-serif"> </span> </span><span style="color:black; font-family:Arial,sans-serif; font-size:11pt"> </span></p>
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<span style="font-size:11.0pt; font-family:"Arial",sans-serif; color:black">IPI is an independent 501(c)(3) nonprofit research organization and an equal opportunity employer. The Institute celebrates diversity and is committed to creating an inclusive environment
for all employees. Interested applicants should apply directly to <span style="background:yellow">
Dr. Rob Meijers by sending cover letter, C.V., and contact information for three references to
</span></span><a href="mailto:rob.meijers@proteininnovation.org"><span style="font-size:11.0pt; font-family:"Arial",sans-serif; color:black; background:yellow">rob.meijers@proteininnovation.org</span></a><span style="font-size:11.0pt; font-family:"Arial",sans-serif; color:black; background:yellow">.</span><span style="font-size:11.0pt; font-family:"Arial",sans-serif; color:black"> </span></p>
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<p class="x_MsoNormal" style="margin-top: 0px; margin-bottom: 0px;margin:0in"><font face="Helvetica Neue"><span style="font-size:14.6667px">For more information about the project:</span></font></p>
<span style="font-family:Arial,Helvetica,sans-serif; font-size:11pt"><a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__proteininnovation.org_2021_11_the-2Dgerman-2Dtranslation-2Dfor-2Dopioid_&d=DwMGaQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=fDKH9Ko4TihOqLU9D1ZXELOzYl7VY8WPCLPWkMJaf6LG429l2eiE8WcRQ7wOK7_C&s=WLq3B1y2OmlK9XDC5qV6AVp-zhU08FTjbNrgy3vRhqM&e=" id="LPlnkOWALinkPreview">https://proteininnovation.org/2021/11/the-german-translation-for-opioid/</a></span></div>
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<a target="_blank" id="LPImageAnchor877656" href="https://urldefense.proofpoint.com/v2/url?u=https-3A__proteininnovation.org_2021_11_the-2Dgerman-2Dtranslation-2Dfor-2Dopioid_&d=DwMGaQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=fDKH9Ko4TihOqLU9D1ZXELOzYl7VY8WPCLPWkMJaf6LG429l2eiE8WcRQ7wOK7_C&s=WLq3B1y2OmlK9XDC5qV6AVp-zhU08FTjbNrgy3vRhqM&e="><img id="LPThumbnailImageId877656" alt="" height="179" width="240" style="display:block" src="https://secureservercdn.net/198.71.233.167/3j1.08d.myftpupload.com/wp-content/uploads/2021/11/iStock-912233802-1.jpg"></a></div>
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<a target="_blank" id="LPUrlAnchor877656" href="https://urldefense.proofpoint.com/v2/url?u=https-3A__proteininnovation.org_2021_11_the-2Dgerman-2Dtranslation-2Dfor-2Dopioid_&d=DwMGaQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=fDKH9Ko4TihOqLU9D1ZXELOzYl7VY8WPCLPWkMJaf6LG429l2eiE8WcRQ7wOK7_C&s=WLq3B1y2OmlK9XDC5qV6AVp-zhU08FTjbNrgy3vRhqM&e=" style="text-decoration:none">The German Translation for Opioid - IPI</a></div>
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The German Translation for Opioid. By Trisha Gura. Note: If you are a postdoc interested in working at IPI on this project, see the job posting here. An opioid crisis in the US is not news. Indeed, the Centers for Disease Control and Prevention estimate nearly
841,000 people in the US have died in the last two decades from a drug overdose, and more than 70% of those deaths involved an opioid.</div>
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proteininnovation.org</div>
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<p style="text-align:right"><span style="font-size:10pt;font-family:"Helvetica","sans-serif"; color:#666D70;">The future of medicine, today.</span></p>
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