<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40">
<head>
<meta http-equiv="Content-Type" content="text/html; charset=us-ascii">
<meta name="Generator" content="Microsoft Word 15 (filtered medium)">
<style><!--
/* Font Definitions */
@font-face
{font-family:"Cambria Math";
panose-1:2 4 5 3 5 4 6 3 2 4;}
@font-face
{font-family:Calibri;
panose-1:2 15 5 2 2 2 4 3 2 4;}
@font-face
{font-family:"Malgun Gothic";
panose-1:2 11 5 3 2 0 0 2 0 4;}
@font-face
{font-family:"\@Malgun Gothic";}
@font-face
{font-family:inherit;
panose-1:0 0 0 0 0 0 0 0 0 0;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{margin:0in;
font-size:11.0pt;
font-family:"Calibri",sans-serif;}
a:link, span.MsoHyperlink
{mso-style-priority:99;
color:#0563C1;
text-decoration:underline;}
p.MsoPlainText, li.MsoPlainText, div.MsoPlainText
{mso-style-priority:99;
mso-style-link:"Plain Text Char";
margin:0in;
font-size:11.0pt;
font-family:"Calibri",sans-serif;}
span.EmailStyle17
{mso-style-type:personal-compose;
font-family:"Calibri",sans-serif;
color:windowtext;}
span.PlainTextChar
{mso-style-name:"Plain Text Char";
mso-style-priority:99;
mso-style-link:"Plain Text";
font-family:"Calibri",sans-serif;}
.MsoChpDefault
{mso-style-type:export-only;}
@page WordSection1
{size:8.5in 11.0in;
margin:1.0in 1.0in 1.0in 1.0in;}
div.WordSection1
{page:WordSection1;}
/* List Definitions */
@list l0
{mso-list-id:887910362;
mso-list-template-ids:-1281085304;}
@list l0:level1
{mso-level-number-format:bullet;
mso-level-text:\F0B7;
mso-level-tab-stop:.5in;
mso-level-number-position:left;
text-indent:-.25in;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l0:level2
{mso-level-number-format:bullet;
mso-level-text:\F0B7;
mso-level-tab-stop:1.0in;
mso-level-number-position:left;
text-indent:-.25in;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l0:level3
{mso-level-number-format:bullet;
mso-level-text:\F0B7;
mso-level-tab-stop:1.5in;
mso-level-number-position:left;
text-indent:-.25in;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l0:level4
{mso-level-number-format:bullet;
mso-level-text:\F0B7;
mso-level-tab-stop:2.0in;
mso-level-number-position:left;
text-indent:-.25in;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l0:level5
{mso-level-number-format:bullet;
mso-level-text:\F0B7;
mso-level-tab-stop:2.5in;
mso-level-number-position:left;
text-indent:-.25in;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l0:level6
{mso-level-number-format:bullet;
mso-level-text:\F0B7;
mso-level-tab-stop:3.0in;
mso-level-number-position:left;
text-indent:-.25in;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l0:level7
{mso-level-number-format:bullet;
mso-level-text:\F0B7;
mso-level-tab-stop:3.5in;
mso-level-number-position:left;
text-indent:-.25in;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l0:level8
{mso-level-number-format:bullet;
mso-level-text:\F0B7;
mso-level-tab-stop:4.0in;
mso-level-number-position:left;
text-indent:-.25in;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l0:level9
{mso-level-number-format:bullet;
mso-level-text:\F0B7;
mso-level-tab-stop:4.5in;
mso-level-number-position:left;
text-indent:-.25in;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l1
{mso-list-id:2010061169;
mso-list-template-ids:1469481696;}
@list l1:level1
{mso-level-number-format:bullet;
mso-level-text:\F0B7;
mso-level-tab-stop:.5in;
mso-level-number-position:left;
text-indent:-.25in;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l1:level2
{mso-level-number-format:bullet;
mso-level-text:\F0B7;
mso-level-tab-stop:1.0in;
mso-level-number-position:left;
text-indent:-.25in;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l1:level3
{mso-level-number-format:bullet;
mso-level-text:\F0B7;
mso-level-tab-stop:1.5in;
mso-level-number-position:left;
text-indent:-.25in;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l1:level4
{mso-level-number-format:bullet;
mso-level-text:\F0B7;
mso-level-tab-stop:2.0in;
mso-level-number-position:left;
text-indent:-.25in;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l1:level5
{mso-level-number-format:bullet;
mso-level-text:\F0B7;
mso-level-tab-stop:2.5in;
mso-level-number-position:left;
text-indent:-.25in;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l1:level6
{mso-level-number-format:bullet;
mso-level-text:\F0B7;
mso-level-tab-stop:3.0in;
mso-level-number-position:left;
text-indent:-.25in;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l1:level7
{mso-level-number-format:bullet;
mso-level-text:\F0B7;
mso-level-tab-stop:3.5in;
mso-level-number-position:left;
text-indent:-.25in;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l1:level8
{mso-level-number-format:bullet;
mso-level-text:\F0B7;
mso-level-tab-stop:4.0in;
mso-level-number-position:left;
text-indent:-.25in;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
@list l1:level9
{mso-level-number-format:bullet;
mso-level-text:\F0B7;
mso-level-tab-stop:4.5in;
mso-level-number-position:left;
text-indent:-.25in;
mso-ansi-font-size:10.0pt;
font-family:Symbol;}
ol
{margin-bottom:0in;}
ul
{margin-bottom:0in;}
--></style><!--[if gte mso 9]><xml>
<o:shapedefaults v:ext="edit" spidmax="1026" />
</xml><![endif]--><!--[if gte mso 9]><xml>
<o:shapelayout v:ext="edit">
<o:idmap v:ext="edit" data="1" />
</o:shapelayout></xml><![endif]-->
</head>
<body lang="EN-US" link="#0563C1" vlink="#954F72" style="word-wrap:break-word">
<div class="WordSection1">
<p class="MsoPlainText">All,<o:p></o:p></p>
<p class="MsoPlainText">Pfizer Structural & Molecular Sciences group (Groton, CT) has an opening for Senior Scientist, cryo-EM (Job ID: 4813142) and the candidate can apply the job in the link below.<o:p></o:p></p>
<p class="MsoPlainText">Thanks in advance for your interest!<o:p></o:p></p>
<p class="MsoPlainText">Seungil Han<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><a href="https://urldefense.com/v3/__https://pfizer.wd1.myworkdayjobs.com/PfizerCareers/job/United-States---Connecticut---Groton/Senior-Scientist--Structural---Molecular-Sciences_4813142-1__;!!Mih3wA!XTfHQci6hPzNygQQNhp_qS74u3hxDvdhioKFmsgIF3i9r4y4iqYtPWDOt3Yr5LjZQw$">https://pfizer.wd1.myworkdayjobs.com/PfizerCareers/job/United-States---Connecticut---Groton/Senior-Scientist--Structural---Molecular-Sciences_4813142-1</a><o:p></o:p></p>
<p class="MsoPlainText"><o:p> </o:p></p>
<p class="MsoPlainText">Senior Scientist - Cryo-EM<o:p></o:p></p>
<p class="MsoPlainText">Job ID: 4813142<o:p></o:p></p>
<p class="MsoPlainText">Location: United States-Connecticut-Groton Role Description<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p style="margin:0in;background:white;vertical-align:baseline"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A">We have an open position at the Senior Scientist level for a cryo-EM position in the Structural and Molecular Sciences
(SMS) group at our Groton, CT Pfizer Research and Development campus. The SMS group is a multidisciplinary group with established expertise in molecular biology, protein biochemistry, protein mass spectrometry, enzymology, NMR, biophysics, protein X-ray crystallography
and cryo-EM. Our mission is to provide integrated molecular insights into drug targets and their interactions (small and large molecule) to advance discovery efforts across multiple therapeutic areas, including Inflammation and Immunology, Vaccines, Cardiovascular
and Metabolic Diseases and Rare Diseases. We are equipped with an FEI Titan Krios microscope, an FEI TF20 microscope, and a dedicated computer cluster and GPU boxes for data processing and refinement. We continue to leverage the capabilities above for broad
portfolio support and impact.<o:p></o:p></span></p>
<p style="margin:0in;background:white;vertical-align:baseline;font-variant-ligatures: normal;font-variant-caps: normal;font-variant-numeric: inherit;font-variant-east-asian: inherit;font-stretch: inherit;line-height:inherit;min-height: 16.08px;orphans: 2;text-align:inherit;white-space:pre-wrap;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A">As a Senior Scientist, you will have broad experience or familiarity with different aspects of structure determination by cryo-EM technology including sample preparation, data collection,
data processing using state-of-art software, and 3-D reconstruction. We are seeking and applicant who is passionate about science in addition to hardware and computing skills associated with EM including microscope, direct electron detector, sample robot,
computer cluster, etc. and their maintenance.<o:p></o:p></span></p>
<p style="margin:0in;background:white;vertical-align:baseline;font-variant-ligatures: normal;font-variant-caps: normal;font-variant-numeric: inherit;font-variant-east-asian: inherit;font-stretch: inherit;line-height:inherit;min-height: 16.08px;orphans: 2;text-align:inherit;white-space:pre-wrap;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A">Equally important will be your ability to collaborate successfully with other scientists in the department and with biologists and chemists in multiple drug discovery teams. The successful
candidate will have opportunities to grow and develop in structure-based drug design and to identify and tackle the critical issues and challenges faced by different drug discovery programs.<o:p></o:p></span></p>
<p style="margin:0in;background:white;vertical-align:baseline"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A"><o:p> </o:p></span></p>
<p class="MsoNormal" style="background:white;vertical-align:baseline"><b><span style="font-size:10.5pt;font-family:"inherit",serif;color:#4A4A4A;border:none windowtext 1.0pt;padding:0in">ROLE RESPONSIBILITIES
</span></b><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A"><o:p></o:p></span></p>
<p class="MsoNormal" style="margin-left:0in;text-indent:-.25in;mso-list:l1 level1 lfo1;background:white;vertical-align:baseline">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:#4A4A4A"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A">* As a member of the EM lab, help manage, maintain, and develop the facility, supports users, and lead collaborative projects aimed at improving our cryo-EM
infrastructure and scientific research programs.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-left:0in;text-indent:-.25in;mso-list:l1 level1 lfo1;background:white;vertical-align:baseline">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:#4A4A4A"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A">* Leverage cryo-EM expertise, provide consultation and guidance to colleagues from other SMS labs for EM studies and serve as a valuable resource for
the entire department.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-left:0in;text-indent:-.25in;mso-list:l1 level1 lfo1;background:white;vertical-align:baseline">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:#4A4A4A"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A">* Independently undertake cryo-EM studies of targets that are of interest to Pfizer. The proposed work will involve all aspects of cryo-EM structure determination
including preparation of suitable grids, analysis by negative staining, cryo-EM data collection, class averaging, 3D-reconstruction and refinement.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-left:0in;text-indent:-.25in;mso-list:l1 level1 lfo1;background:white;vertical-align:baseline">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:#4A4A4A"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A">* Deliver novel scientific insights for the design of small molecule ligands as well as protein therapeutics and/or antigens.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-left:0in;text-indent:-.25in;mso-list:l1 level1 lfo1;background:white;vertical-align:baseline">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:#4A4A4A"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A">* Establish productive collaborations with other SMS colleagues and form partnerships with colleagues from research units and other departments.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-left:0in;text-indent:-.25in;mso-list:l1 level1 lfo1;background:white;vertical-align:baseline">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:#4A4A4A"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A">* Rapidly advance projects by timely problem solving and crisp decision making.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-left:0in;text-indent:-.25in;mso-list:l1 level1 lfo1;background:white;vertical-align:baseline">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:#4A4A4A"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A">* Clearly communicate with project team members and other Pfizer colleagues.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-left:0in;text-indent:-.25in;mso-list:l1 level1 lfo1;background:white;vertical-align:baseline">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:#4A4A4A"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A">* Consistently record your experimental results in an electronic laboratory notebook and comply with all Pfizer safety policies.<o:p></o:p></span></p>
<p class="MsoNormal" style="background:white;vertical-align:baseline"><b><span style="font-size:10.5pt;font-family:"inherit",serif;color:#4A4A4A;border:none windowtext 1.0pt;padding:0in"><o:p> </o:p></span></b></p>
<p class="MsoNormal" style="background:white;vertical-align:baseline"><b><span style="font-size:10.5pt;font-family:"inherit",serif;color:#4A4A4A;border:none windowtext 1.0pt;padding:0in">QUALIFICATIONS
</span></b><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A"><o:p></o:p></span></p>
<p class="MsoNormal" style="margin-left:0in;text-indent:-.25in;mso-list:l0 level1 lfo2;background:white;vertical-align:baseline">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:#4A4A4A"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A">* Doctoral degree or equivalent in Biochemistry, Biophysics, Physics, Chemistry or related field.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-left:0in;text-indent:-.25in;mso-list:l0 level1 lfo2;background:white;vertical-align:baseline">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:#4A4A4A"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A">* 0-3 years of cryo-EM postdoctoral research experience (or equivalent) in academia or industry.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-left:0in;text-indent:-.25in;mso-list:l0 level1 lfo2;background:white;vertical-align:baseline">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:#4A4A4A"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A">* Proven ability to independently design and conduct state-of-the-art single particle cryo-EM experiments, leading to a strong track record of successful
outcomes with publications in top tier journals.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-left:0in;text-indent:-.25in;mso-list:l0 level1 lfo2;background:white;vertical-align:baseline">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:#4A4A4A"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A">* Must be able to thrive and deliver results in a fast paced, dynamic and highly multi-tasking environment.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-left:0in;text-indent:-.25in;mso-list:l0 level1 lfo2;background:white;vertical-align:baseline">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:#4A4A4A"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A">* Broad knowledge in protein characterization, structural biology, biophysics and computational chemistry.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-left:0in;text-indent:-.25in;mso-list:l0 level1 lfo2;background:white;vertical-align:baseline">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:#4A4A4A"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A">* Demonstrated ability to work independently and in teams in an inclusive manner.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-left:0in;text-indent:-.25in;mso-list:l0 level1 lfo2;background:white;vertical-align:baseline">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:#4A4A4A"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A">* Proven scientific influence via strong interpersonal and communication skills; passionate about using structural data to influence key scientific decisions.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-left:0in;text-indent:-.25in;mso-list:l0 level1 lfo2;background:white;vertical-align:baseline">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol;color:#4A4A4A"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A">* Has the skill and drive to grow into a thought leader.<o:p></o:p></span></p>
<p style="margin:0in;background:white;vertical-align:baseline"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#4A4A4A"><o:p> </o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
</div>
</body>
</html>