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<p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:#000000;font-weight:400">Dear all,</span></p>
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<p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:#000000;font-weight:400">We are pleased to announce the establishment of the Simons Machine Learning Center (SMLC) at the New York Structural
Biology Center. SMLC is a machine learning research group dedicated to advancing all aspects of structural biology. Within cryo-EM, we are continuing to develop algorithms for micrograph and tomogram analysis and are expanding our efforts to automating and
optimizing cryo-EM and cryo-ET data collection with machine learning.</span></p>
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<p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><a href="https://urldefense.com/v3/__https://smlc.nysbc.org/__;!!Mih3wA!Q38INFdXph2NJ9CnkgLUOEn_ZLRczWDoJJHoF0MpMkqHznYBdiDvMtu0shfMpS21-Q$"><span style="font-size:11pt;font-family:Arial;color:#1155cc;font-weight:400;text-decoration:underline;text-decoration-skip-ink:none">https://smlc.nysbc.org</span></a></p>
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<p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:#000000;font-weight:400">SMLC is accepting applications for Postdoc and Research Scientist positions. Scientists with strong quantitative
backgrounds who are interested in machine learning and structural biology are encouraged to apply. Relevant experience in machine learning, computer vision, natural language processing, computational biology (esp. relating to structural biology), cryo-EM/ET,
or other related disciplines is a plus. Successful candidates will be highly motivated, independent scientists with significant programming experience and preferably with some cryo-EM or structural biology experience. Internships are available for graduate
and undergraduate students.</span></p>
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<p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:#000000;font-weight:400">SMLC is funded through the Simons Foundation and is housed within the Simons Electron Microscopy Center (SEMC),
a premier local, national, and international cryo-EM research facility located in Manhattan. SEMC is equipped with 7 Titan Krioses, 1 Glacios, 1 Aquilos2 cryo-FIB/SEM, 1 Helios cryo-FIB/SEM, a Zeiss Airyscan2, a PRIMO grid micropatterning system, several screening
microscopes, Spotiton and Chameleon grid plunging robots, and substantial computing resources. Recent publications by the SMLC team exemplify the success of ML in cryo-EM:</span></p>
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<p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><a href="https://urldefense.com/v3/__https://smlc.nysbc.org/publications/__;!!Mih3wA!Q38INFdXph2NJ9CnkgLUOEn_ZLRczWDoJJHoF0MpMkqHznYBdiDvMtu0sheaEe-y4A$"><span style="font-size:11pt;font-family:Arial;color:#1155cc;font-weight:400;text-decoration:underline;text-decoration-skip-ink:none">https://smlc.nysbc.org/publications/</span></a></p>
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<p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:#000000;font-weight:400">If interested, please contact Tristan Bepler directly: tbepler@nysbc.org. Research Scientist and Postdoc candidates
should provide their CV, a brief letter of motivation, and contact details of three references. Please see the attached job posting for further details. Applications will remain open until positions are filled.</span></p>
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<p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:#000000;font-weight:400">We look forward to you joining our team,</span></p>
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<p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:#000000;font-weight:400">Tristan Bepler, Group Leader, Simons Machine Learning Center</span></p>
<p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:#000000;font-weight:400">Alex Noble, Group Leader, SEMC</span></p>
<p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:#000000;font-weight:400">Bridget Carragher, SEMC Co-director</span></p>
<p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:11pt;font-family:Arial;color:#000000;font-weight:400">Clint Potter, SEMC Co-director</span></p>
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