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<!--StartFragment--><p class="MsoNormal" style="line-height:150%">Dear colleagues, </p><p class="MsoNormal" style="text-align:justify;line-height:150%">The Jinek laboratory at the University of Zurich, Switzerland, has a vacancy for a postdoctoral researcher in cryo-EM studies of protein-nucleic acid complexes. We are looking for a talented, goal-driven and team-oriented scientist with a strong background in single-particle cryoelectron microscopy. Research in the Jinek laboratory is focused on studying the molecular structures and mechanisms of CRISPR-Cas and related genome defense and editing systems, as well as eukaryotic mRNA processing machineries. These biological questions are investigated using an integrative approach combining structural biology (X-ray crystallography and increasingly cryo-EM), biochemical and biophysical experiments, and functional studies in cell-based models. As of January 2020, the lab has regular access to a FEI Titan Krios (equipped with a K3 camera) in the Department of Biochemistry and the Center for Microscopy and Image Analysis at the University of Zurich.</p><p class="MsoNormal" style="text-align:justify;line-height:150%">The postdoctoral researcher will manage and conduct
their independent research project within the main research focus areas of the
Jinek laboratory. The researcher is also expected to contribute expertise in
single-particle cryo-EM in support of ongoing collaborative projects in the
laboratory, closely interacting with PhD students and other postdoctoral
researchers in the group. The laboratory has several collaborative projects
that would provide excellent training opportunities in complementary structural
biology approaches such as X-ray crystallography or biochemical studies.</p><p class="MsoNormal" style="text-align:justify;line-height:150%">Interested candidates should have extensive hands-on
experience in cryo-EM sample preparation and expertise in processing of
single-particle data. Experience with biochemical methods, especially protein
expression and purification in bacteria and insect cells would be an advantage.</p><p class="MsoNormal" style="text-align:justify;line-height:150%">The position offers a competitive employment package,
a supportive and highly collaborative working environment, excellent research
funding and state-of-the art infrastructure. Zurich is a major European
research hub that also offers an exceptionally high quality of life.</p><p class="MsoNormal" style="text-align:justify;line-height:150%"><span lang="EN-GB" class="">Applicants must
hold a PhD in biochemistry or structural biology, and have a strong research track
record. Please send your cover letter and a CV, along with contact details for
two references, to Martin Jinek (</span><span lang="EN-GB" class=""><a href="mailto:jinek@bioc.uzh.ch" class="">jinek@bioc.uzh.ch</a></span><span lang="EN-GB" class="">).</span></p><p class="MsoNormal" style="text-align:justify;line-height:150%"><span lang="EN-GB" class="">With best wishes,<o:p class=""></o:p></span></p><p class="MsoNormal" style="text-align:justify;line-height:150%"><span lang="EN-GB" class="">Martin Jinek<o:p class=""></o:p></span></p>
<!--EndFragment--><div class="">
<div style="word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class=""><div style="color: rgb(0, 0, 0); font-family: Helvetica; font-size: 14px; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px;">----------------------------------------------<br class="">Martin Jinek<br class="">Associate Professor<span class="Apple-tab-span" style="white-space: pre;"> </span><br class="">University of Zurich<br class="">Department of Biochemistry<br class="">Winterthurerstrasse 190<br class="">CH-8057 Zurich<br class="">Switzerland<br class="">Tel. +41-44-6355572<br class="">Fax +41-44-6356805<br class=""><a href="mailto:jinek@bioc.uzh.ch" class="">E-mail: jinek@bioc.uzh.ch</a><br class="">Web: http://www.bioc.uzh.ch<br class="">----------------------------------------------</div></div>
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