<div dir="ltr"><div class="gmail_quote"><div dir="ltr" class="gmail_attr">Dear all,<br></div><div lang="EN-US" link="#6CAAE3" vlink="#6CAAE3"><div><p class="MsoNormal"><u></u></p>
<p class="MsoNormal">Our next Ask the Experts session will be on GPCR structure determination by cryo-EM. Please join us!<u></u><u></u></p>
<p class="MsoNormal">Best regards,<u></u><u></u></p>
<p class="MsoNormal">Kasim<u></u><u></u></p>
<p class="MsoNormal"><u></u> <u></u></p>
<p class="MsoNormal"><b>Dr. Kasim Sader</b><u></u><u></u></p>
<p class="MsoNormal">Applications Manager<u></u><u></u></p>
<p class="MsoNormal">Pharma Cryo-EM<u></u><u></u></p>
<p class="MsoNormal">Thermo Fisher Scientific<u></u><u></u></p>
<p class="MsoNormal">Tel <a href="tel:07342%20882058" target="_blank"><span style="color:blue">+447342882058</span></a><u></u><u></u></p>
<p class="MsoNormal"><a href="mailto:kasim.sader@thermofisher.com" target="_blank"><span style="color:blue">kasim.sader@thermofisher.com</span></a><u></u><u></u></p>
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<p class="MsoNormal" style="line-height:21.0pt"><b><span style="font-size:15.0pt;font-family:"Arial",sans-serif;color:#ee3134">Join a discussion on sub-2.5 Å cryo-EM structure determination of GPCRs for drug design</span></b><u></u><u></u></p>
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<p class="MsoNormal" style="line-height:15.0pt"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#555759">Wed, Sep 9, 2020, 8 p.m. EDT | 5 p.m. PDT | 10 a.m. AEST | 9 a.m. JST</span></b><u></u><u></u></p>
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<p class="MsoNormal" style="line-height:15.0pt"><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:#333333"> </span><u></u><u></u></p>
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<p class="MsoNormal" style="line-height:15.0pt"><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:#333333">Attend our upcoming
<em><span style="font-family:"Arial",sans-serif">Ask the Experts</span></em> Q&A session on routine sub-2.5 Å cryo-EM structure determination of GPCRs for drug design. This rapidly developing field is constantly producing new and exciting biological and pharmacological
 discoveries. Ask questions and get answers from leading academic investigators in the field.</span><span style="font-family:"Arial",sans-serif"><u></u><u></u></span></p>
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<p class="MsoNormal" style="line-height:15.0pt"><span style="font-family:"Arial",sans-serif;color:black"> </span><span style="font-family:"Arial",sans-serif"><u></u><u></u></span></p>
<p class="MsoNormal" style="line-height:125%"><span style="font-size:10.0pt;line-height:125%;font-family:"Arial",sans-serif;color:black">This session will cover everything from GPCR biology, sample preparation, imaging, and 3D </span><span style="color:black;font-family:Arial,sans-serif;font-size:10pt">reconstruction, and in particular
 the recent 2.1 Å GLP-1R structure and paper on experimental cryo-EM parameters for routine high resolutions GPCRs:</span></p>
<p class="MsoNormal" style="line-height:125%"><span style="font-size:10.0pt;line-height:125%;font-family:"Arial",sans-serif;color:black"><a href="https://urldefense.com/v3/__https://www.biorxiv.org/content/10.1101/2020.08.16.252585v1__;!!Mih3wA!SWwj5SD2Z5wc7Td9P2PdxMsN9wYBAcYd7PHwA_DWPT_8w0f6O1Y2498jt5cFO-2aog$" target="_blank">https://www.biorxiv.org/content/10.1101/2020.08.16.252585v1</a></span><span style="font-family:"Arial",sans-serif"><u></u><u></u></span></p>
<p class="MsoNormal" style="line-height:125%"><span style="font-size:10.0pt;line-height:125%;font-family:"Arial",sans-serif;color:black"><a href="https://urldefense.com/v3/__https://www.biorxiv.org/content/10.1101/2020.08.21.260851v1__;!!Mih3wA!SWwj5SD2Z5wc7Td9P2PdxMsN9wYBAcYd7PHwA_DWPT_8w0f6O1Y2498jt5crzKyAmg$" target="_blank">https://www.biorxiv.org/content/10.1101/2020.08.21.260851v1</a></span><span style="font-family:"Arial",sans-serif"><u></u><u></u></span></p>
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<p class="MsoNormal" align="center" style="text-align:center"><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:black"><a href="https://urldefense.com/v3/__http://app.em.thermofisher.com/e/er?s=34830204&lid=3815&elqTrackId=9af26823e8e74b9fbb514cffbb6344a3&elq=a250bd7c144e4257ba60780ebce90b58&elqaid=1342&elqat=1__;!!Mih3wA!SWwj5SD2Z5wc7Td9P2PdxMsN9wYBAcYd7PHwA_DWPT_8w0f6O1Y2498jt5eli6n09Q$" target="_blank"><b><span style="font-size:13.0pt;color:white;border:solid #ee3134 1.0pt;padding:5.0pt;text-decoration:none"> Register
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<p class="MsoNormal" style="line-height:15.0pt"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#555759">Presenter information</span></b><u></u><u></u></p>
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<p class="MsoNormal" style="line-height:15.0pt"><strong><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:#333333">Host:</span></strong><b><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:#333333"><br>
</span></b><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:#333333">Suzanne Graham, Senior Director of Global Business Development, Electron Microscopy, Thermo Fisher Scientific</span><u></u><u></u></p>
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<p class="MsoNormal" style="line-height:15.0pt"><strong><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:#333333">Panelists:</span></strong><u></u><u></u></p>
<p class="MsoNormal" style="line-height:15.0pt"><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:#333333">Denise Wootten, Associate Professor, Drug Discovery Biology, Monash University</span><u></u><u></u></p>
<p class="MsoNormal" style="line-height:15.0pt"><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:#333333">Patrick Sexton, Professor, Drug Discovery Biology, Monash University<b><br>
</b>Radostin Danev, Professor, Cryo-EM, University of Tokyo<br>
Jeffrey Lengyel, Principal Scientist, Cryo-EM, Thermo Fisher Scientific</span><u></u><u></u></p>
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