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<p class="MsoNormal"><span style="font-size:11.0pt">Dear colleagues,<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt">A cryo-EM specialist position at Harvard Medical School is currently available. Interested candidates should submit a cover letter, CV, and contact information for two references, to the director, Dr. Stephen
Harrison, via <a href="mailto:schadmin@crystal.harvard.edu">schadmin@crystal.harvard.edu</a>. In the Subject line of your email, please write: Cryo-EM Specialist.<o:p></o:p></span></p>
<div style="mso-element:para-border-div;border:none;border-bottom:dotted windowtext 3.0pt;padding:0in 0in 0in 0in">
<p class="MsoNormal" style="border:none;padding:0in"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
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<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><span style="font-size:11.0pt;font-family:"Arial",sans-serif">Cryo-EM Specialist position<o:p></o:p></span></b></p>
<p class="MsoNormal" style="line-height:115%;background:white"><span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif;color:black"><o:p> </o:p></span></p>
<p class="MsoNormal" style="line-height:115%;background:white"><span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif;color:black">Harvard Medical School houses two core facilities providing access to negative stain and cryo-EM instrumentation;
we are looking for a highly motivated scientist to join our team. The Harvard Cryo-EM Center for Structural Biology, formed as a consortium between HMS, Boston Children's Hospital, Dana-Farber Cancer Institute, and Massachusetts General Hospital, serves the
consortium members and a variety of external academic and commercial users. The Molecular Electron Microscopy Suite is a training resource for Quad-based researchers at Harvard Medical School (<a href="https://urldefense.com/v3/__https://cryoem.hms.harvard.edu/__;!!Mih3wA!UAIezBn3EM4lCGve9HYROWvTcKFWSWdKlNF0HKwqZN2Z78cnzhm8uTVczqqHypg_pw$">https://cryoem.hms.harvard.edu/</a>).
The successful candidate will provide support and training for researchers seeking to learn cryo-EM and negative-stain EM in these two facilities, serving as an interface between the instrumentation and a vibrant scientific community. The candidate will work
closely with a team of scientists to support COVID-19 and related projects in many research areas and will take on facility management responsibilities.<o:p></o:p></span></p>
<p class="MsoNormal" style="line-height:115%;background:white"><span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif;color:black"><o:p> </o:p></span></p>
<p class="MsoNormal" style="line-height:115%;background:white"><span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif;color:black">Key Roles:<o:p></o:p></span></p>
<ul style="margin-top:0in" type="disc">
<li class="MsoListParagraphCxSpFirst" style="color:black;margin-left:0in;mso-add-space:auto;line-height:115%;mso-list:l0 level1 lfo3;background:white">
<span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif">Serve as the technical interface between users and the Talos Arctica and Titan Krios microscopes by loading samples and checking microscope alignments.<o:p></o:p></span></li><li class="MsoListParagraphCxSpMiddle" style="color:black;margin-left:0in;mso-add-space:auto;line-height:115%;mso-list:l0 level1 lfo3;background:white">
<span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif">Train users to operate TEM microscopes, specifically the Tecnai T12, Talos Arctica, and Titan Krios; including sample preparation (negative stain and cryo-plunging), grid loading,
sample screening, and data collection.<o:p></o:p></span></li><li class="MsoListParagraphCxSpMiddle" style="color:black;margin-left:0in;mso-add-space:auto;line-height:115%;mso-list:l0 level1 lfo3;background:white">
<span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif">Advise researchers on experimental strategy and, when appropriate, collaborate with them to assist in data acquisition, analysis and structure determination, particularly with COVID-19-related
work.<o:p></o:p></span></li><li class="MsoListParagraphCxSpLast" style="color:black;margin-left:0in;mso-add-space:auto;line-height:115%;mso-list:l0 level1 lfo3;background:white">
<span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif">Interact closely with the core facilities’ team to manage microscope and equipment maintenance, coordinate user scheduling and training, and interface with SBGrid to assist with
the computational needs of both facilities.<o:p></o:p></span></li></ul>
<p class="MsoNormal" style="line-height:115%;background:white"><span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif;color:black"> <o:p></o:p></span></p>
<p class="MsoNormal" style="line-height:115%;background:white"><span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif;color:black">This position will have a high degree of independence, opportunities to present at regional and national
scientific symposia and workshops, and opportunities to develop collaborative relationships with Harvard community investigators.<o:p></o:p></span></p>
<p class="MsoNormal" style="line-height:115%;background:white"><span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif;color:black"><o:p> </o:p></span></p>
<p class="MsoNormal" style="line-height:115%;background:white"><span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif;color:black">Requirements:<o:p></o:p></span></p>
<ul style="margin-top:0in" type="disc">
<li class="MsoListParagraphCxSpFirst" style="color:black;margin-left:0in;mso-add-space:auto;line-height:115%;mso-list:l3 level1 lfo6;background:white">
<span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif">Ph.D. in a field related to structural biology such as cell biology or biochemistry. Experience in structural biology at the postdoctoral level is desired.
<o:p></o:p></span></li><li class="MsoListParagraphCxSpMiddle" style="color:black;margin-left:0in;mso-add-space:auto;line-height:115%;mso-list:l3 level1 lfo6;background:white">
<span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif">Experience with negative stain EM and cryo-EM. Cryo-electron tomography practical application and analysis experience is valuable.<o:p></o:p></span></li><li class="MsoListParagraphCxSpMiddle" style="color:black;margin-left:0in;mso-add-space:auto;line-height:115%;mso-list:l3 level1 lfo6;background:white">
<span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif">Must be detail-oriented and able to manage multiple projects simultaneously.<o:p></o:p></span></li><li class="MsoListParagraphCxSpLast" style="color:black;margin-left:0in;mso-add-space:auto;line-height:115%;mso-list:l3 level1 lfo6;background:white">
<span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif">Good communication and interpersonal skills.<o:p></o:p></span></li></ul>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal" style="line-height:115%"><span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif">Harvard is an Affirmative Action/Equal Opportunity Employer. Applications from women and minority candidates are strongly encouraged.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions or
any other characteristic protected by law.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt"><o:p> </o:p></span></p>
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