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</o:shapelayout></xml><![endif]--></head><body lang=EN-US link="#0563C1" vlink="#954F72"><div class=WordSection1><p class=MsoNormal><span style='color:black'>Dear all, <o:p></o:p></span></p><p class=MsoNormal><span style='color:black'> <o:p></o:p></span></p><p class=MsoNormal><b><span style='color:black'>RESPONSE TO COVID-19 EMERGENCY – Call for CryoEM Proposals</span></b><span style='color:black'><o:p></o:p></span></p><p class=MsoNormal><span style='color:black'> <o:p></o:p></span></p><p class=MsoNormal><b><span style='color:black'>eBIC at Diamond Light Source is offering free remote access to our CryoEM instruments for SPA, CryoET and CryoFIB/SEM. In addition a range of synchrotron instruments available at Diamond (see below) to help research aimed at combatting the COVID-19 outbreak. Proposals are subject to light touch rapid review. This applies equally to users from all countries.</span></b><span style='color:black'><o:p></o:p></span></p><p class=MsoNormal><b><span style='color:black'> </span></b><span style='color:black'><o:p></o:p></span></p><p class=MsoNormal><b><span style='color:black'>The short rapid access proposal can be accessed here: </span></b><a href="https://www.diamond.ac.uk/covid-19/for-scientists/rapid-access.html"><b><span style='color:#0563C1'>https://www.diamond.ac.uk/covid-19/for-scientists/rapid-access.html</span></b></a><span style='color:black'><o:p></o:p></span></p><p class=MsoNormal><b><span style='color:black'> </span></b><span style='color:black'><o:p></o:p></span></p><p class=MsoNormal><span style='color:black'> <o:p></o:p></span></p><p class=MsoNormal><b><span style='color:black'>Details:</span></b><span style='color:black'><o:p></o:p></span></p><p class=MsoNormal><span style='color:black'>In line with UK government recommendations to help slow down the spread of the COVID-19 disease (</span><a href="https://www.gov.uk/coronavirus"><span style='color:#954F72'>https://www.gov.uk/coronavirus</span></a><span style='color:black'>) Diamond will be running restricted operations for the foreseeable future and will not be accommodating any users on site.<o:p></o:p></span></p><p class=MsoNormal><span style='color:black'> <o:p></o:p></span></p><p class=MsoNormal><span style='color:black'>For the month of April we are aiming to perform only remote access work relevant to the COVID-19 outbreak. We are running a limited service with Instruments available according to demand at eBIC for SPA and CryoET. We are also happy to discuss proposals for CryoFIB milling of samples for tomography.<o:p></o:p></span></p><p class=MsoNormal><span style='color:black'><o:p> </o:p></span></p><p class=MsoNormal><b><span style='color:black'>CryoEM:</span></b><span style='color:black'> </span><a href="https://www.diamond.ac.uk/Instruments/Biological-Cryo-Imaging/eBIC.html">https://www.diamond.ac.uk/Instruments/Biological-Cryo-Imaging/eBIC.html</a><span style='color:black'><o:p></o:p></span></p><p class=MsoNormal><span style='color:black'><o:p> </o:p></span></p><p class=MsoNormal><span style='color:black'>For your information the following synchrotron based techniques are also providing remote access for COVID-19 based research:<o:p></o:p></span></p><p class=MsoNormal><span style='color:black'><o:p> </o:p></span></p><p class=MsoNormal><b><span style='color:black'>cryo MX beamlines</span></b><span style='color:black'>: </span><a href="https://www.diamond.ac.uk/Instruments/Mx.html"><span style='color:#0563C1'>https://www.diamond.ac.uk/Instruments/Mx.html</span></a><span style='color:black'><o:p></o:p></span></p><p class=MsoNormal><b><span style='color:black'> </span></b><span style='color:black'><o:p></o:p></span></p><p class=MsoNormal><b><span style='color:black'>XChem</span></b><span style='color:black'>: </span><a href="https://www.diamond.ac.uk/Instruments/Mx/Fragment-Screening.html"><span style='color:#0563C1'>https://www.diamond.ac.uk/Instruments/Mx/Fragment-Screening.html</span></a><span style='color:black'><o:p></o:p></span></p><p class=MsoNormal><b><span style='color:black'> </span></b><span style='color:black'><o:p></o:p></span></p><p class=MsoNormal><b><span style='color:black'> </span></b><span style='color:black'><o:p></o:p></span></p><p class=MsoNormal><b><span style='color:black'>Cryo X-ray Microscopy and Cryo Super resolution microscopy (incl CLXM & CLEM):</span></b><span style='color:black'><o:p></o:p></span></p><p class=MsoNormal><a href="https://www.diamond.ac.uk/Instruments/Biological-Cryo-Imaging/B24.html"><span style='color:#954F72'>https://www.diamond.ac.uk/Instruments/Biological-Cryo-Imaging/B24.html</span></a><span style='color:black'><o:p></o:p></span></p><p class=MsoNormal><b><span style='color:black'> </span></b><span style='color:black'><o:p></o:p></span></p><p class=MsoNormal><b><span style='color:black'>BioSAXS:</span></b><span style='color:black'> </span><a href="https://www.diamond.ac.uk/Instruments/Soft-Condensed-Matter/small-angle/B21.html"><span style='color:#0563C1'>https://www.diamond.ac.uk/Instruments/Soft-Condensed-Matter/small-angle/B21.html</span></a><span style='color:black'><o:p></o:p></span></p><p class=MsoNormal><b><span style='color:black'> </span></b><span style='color:black'><o:p></o:p></span></p><p class=MsoNormal><b><span style='color:black'>Circular Dichroism</span></b><span style='color:black'>: </span><a href="https://www.diamond.ac.uk/Instruments/Soft-Condensed-Matter/B23.html"><span style='color:#0563C1'>https://www.diamond.ac.uk/Instruments/Soft-Condensed-Matter/B23.html</span></a><span style='color:black'><o:p></o:p></span></p><p class=MsoNormal><span style='color:black'> <o:p></o:p></span></p><p class=MsoNormal>Best,<o:p></o:p></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal style='margin-bottom:.5pt;background:white'><b><span lang=EN-GB style='font-size:8.0pt;font-family:"Lucida Calligraphy";color:black;background:white;mso-fareast-language:EN-GB'>Peijun Zhang</span></b><b><span lang=EN-GB style='font-size:8.0pt;font-family:"Lucida Calligraphy";color:black;background:white;mso-fareast-language:EN-GB'><o:p></o:p></span></b></p><p class=MsoNormal style='margin-bottom:.5pt'><span style='font-size:8.0pt'>Professor</span><span lang=EN-GB style='font-size:8.0pt'><o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:.5pt'><span style='font-size:8.0pt'>Division of Structural Biology</span><span lang=EN-GB style='font-size:8.0pt'><o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:.5pt'><span style='font-size:8.0pt'>Nuffield Department of Medicine<o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:.5pt'><span style='font-size:8.0pt'>University of Oxford</span><span lang=EN-GB style='font-size:8.0pt'><o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:.5pt'><span style='font-size:8.0pt'>Roosevelt Drive Oxford OX3 7BN, UK</span><span lang=EN-GB style='font-size:8.0pt'><o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:.5pt'><a href="mailto:peijun@strubi.ox.ac.uk" target="_blank"><span style='font-size:8.0pt;color:#3366FF'>peijun@strubi.ox.ac.uk</span></a><span style='color:#3366FF'><o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:.5pt'><a href="https://ndm.medsci.ox.ac.uk/people/peijun-zhang"><span style='font-size:8.0pt;color:#3366FF'>https://ndm.medsci.ox.ac.uk/people/peijun-zhang</span></a><o:p></o:p></p><p class=MsoNormal style='margin-bottom:.5pt'><span lang=EN-GB style='font-size:8.0pt'><o:p> </o:p></span></p><p class=MsoNormal style='margin-bottom:.5pt'><span style='font-size:8.0pt'>Director</span><span lang=EN-GB style='font-size:8.0pt'><o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:.5pt'><span style='font-size:8.0pt'>Electron Bio-Imaging Centre (eBIC)</span><span lang=EN-GB style='font-size:8.0pt'><o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:.5pt'><span style='font-size:8.0pt'>Diamond Light Source</span><span lang=EN-GB style='font-size:8.0pt'><o:p></o:p></span></p><p class=MsoNormal><span lang=EN-GB style='font-size:8.0pt;color:#3366FF'><a href="https://www.diamond.ac.uk/Instruments/Biological-Cryo-Imaging/eBIC.html"><span style='color:#3366FF'>https://www.diamond.ac.uk/Instruments/Biological-Cryo-Imaging/eBIC.html</span></a><o:p></o:p></span></p><p class=MsoNormal><o:p> </o:p></p></div></body></html>