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<!--StartFragment--><p class="MsoNormal" style="line-height:150%">Dear colleagues,</p><p class="MsoNormal" style="text-align:justify;line-height:150%">The Jinek laboratory at the University of
Zurich, Switzerland, is looking for a talented, goal-driven and team-oriented postdoctoral
researcher with a strong background in single-particle cryoelectron microscopy.
Research in the Jinek laboratory is focused on studying the molecular structures
and mechanisms of CRISPR-Cas and related bacterial defense systems, as well as
eukaryotic mRNA processing machineries by cryo-EM. These biological questions are
investigated using an integrative approach combining structural biology (X-ray
crystallography and increasingly cryo-EM), biochemical and biophysical
experiments, and functional studies in cell-based models. As of January 2020,
the Jinek lab has regular access to a brand-new FEI Titan Krios (equipped with
a K3 camera) in the Department of Biochemistry at the University of Zurich.</p><p class="MsoNormal" style="text-align:justify;line-height:150%">The postdoctoral researcher will manage and conduct their
independent research project within the main research focus areas of the host
laboratory. The researcher is also expected to contribute expertise in
single-particle cryo-EM in support of ongoing collaborative projects in the
laboratory, closely interacting with PhD students and other postdocs in the group. The laboratory has several exciting projects
that would also provide excellent training opportunities in complementary structural
biology approaches such as X-ray crystallography or biochemical studies.</p><p class="MsoNormal" style="text-align:justify;line-height:150%">Interested candidates should have hands-on experience
in cryo-EM sample preparation and expertise in processing single-particle
data. Experience with biochemical methods, especially protein expression and
purification in bacteria and insect cells would be an advantage.</p><p class="MsoNormal" style="text-align:justify;line-height:150%">The position offers a competitive employment package,
a supportive and highly collaborative working environment, excellent research
funding and state-of-the art infrastructure. Zurich is a major European
research hub that also offers an exceptionally high quality of life.</p><p class="MsoNormal" style="text-align:justify;line-height:150%"><span lang="EN-GB" class="">Applicants must
hold a PhD in biochemistry or structural biology, and have a strong research track
record. Please send your cover letter and a CV, along with contact details of
two referees, to Martin Jinek (</span><span lang="EN-GB" class=""><a href="mailto:jinek@bioc.uzh.ch" class="">jinek@bioc.uzh.ch</a></span><span lang="EN-GB" class="">).<o:p class=""></o:p></span></p>
<!--EndFragment--><p class="MsoNormal" style="line-height:150%"><span style="text-align: justify;" class="">With best wishes,</span></p><p class="MsoNormal" style="text-align:justify;line-height:150%"><span lang="EN-GB" class="">Martin Jinek<o:p class=""></o:p></span></p>
<!--EndFragment--><div class=""><div style="color: rgb(0, 0, 0); font-family: Helvetica; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-variant-east-asian: normal; font-variant-position: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;" class=""><div class="">----------------------------------------------</div><div class="">Martin Jinek</div><div class="">Associate Professor<span class="Apple-tab-span" style="white-space: pre;"> </span></div><div class="">University of Zurich</div><div class="">Department of Biochemistry</div><div class="">Winterthurerstrasse 190</div><div class="">CH-8057 Zurich</div><div class="">Switzerland</div><div class="">Tel. +41-44-6355572</div><div class="">Fax +41-44-6356805</div><div class=""><a href="mailto:jinek@bioc.uzh.ch" class="">E-mail: jinek@bioc.uzh.ch</a></div><div class="">Web: <a href="http://www.bioc.uzh.ch" class="">http://www.bioc.uzh.ch</a></div><div class="">----------------------------------------------</div></div>
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